Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$70K - $125K *
Unlock potential by translating P&IDs and design documents into precise pipe fabrication drawings for industrial projects. Collaborate with teams to ensure accuracy and efficiency throughout the proje...
5 days ago
$95K - $105K *
Unlock potential by providing financial analysis and operational support for a complex government contract. Collaborate with leadership and teams to ensure effective budgeting, reporting, and subcontr...
5 days ago
$100K - $105K *
Transform the testing landscape by designing and implementing robust testing methods for IT products, ensuring they meet specifications while collaborating with developers and users to enhance quality...
5 days ago
$100K - $105K *
Join a team that's dedicated to optimizing fleet operations and leading maintenance efforts. Oversee daily repairs, manage a skilled team, ensure safety compliance, and enhance customer relationships...
5 days ago
Sr Acquisition Specialist (R&D)
$110K - $130K *
Take ownership of R&D acquisition support for the NGA, managing budgeting, planning, and financial execution. Collaborate with technical teams to ensure effective program management and compliance wit...
5 days ago
$95K - $115K *
Contribute to impactful communications by crafting precise technical documents for government programs. Collaborate with leadership to ensure adherence to standards while enhancing strategic partnersh...
5 days ago
$150K - $180K *
Lead transformative Legal GenAI initiatives, guiding corporate legal departments in strategy, tool selection, and implementation. Collaborate with senior stakeholders to enhance legal service delivery...
5 days ago
Staff Software Development Engineer in Test
$160K - $200K *
Advance quality engineering by leading automation architecture and strategy across teams. Collaborate with Engineering and Product to enhance testing practices, ensuring high standards and effective r...
5 days ago
Physical Therapist Home Health
$80K - $95K *
Elevate patient care by delivering tailored physical therapy solutions, enhancing mobility and quality of life. Collaborate with a dedicated team to ensure effective treatment plans and maintain high...
5 days ago
System Manager of Enterprise Resilience
$100K - $120K *
Lead the charge in enhancing enterprise-wide Business Continuity programs, ensuring critical healthcare services remain uninterrupted. Collaborate across teams to strengthen resilience and deliver mea...
Reposted 5 days ago
Sr. Manager Talent Management and HRBPs
$125K - $145K *
Lead the charge in shaping talent management strategies while guiding HR Business Partners. Drive performance management, succession planning, and employee engagement initiatives to enhance organizati...
5 days ago
$75K - $90K *
Drive your career with a Business Process Analyst role focused on enhancing wireless network operations through process analysis, mapping, and stakeholder collaboration to identify and implement impro...
5 days ago
Complex Claim Specialist, New York Labor Law
$135K - $165K *
Tackle complex general liability claims by evaluating coverage issues, managing risks, and formulating resolution strategies. Collaborate with internal and external parties to ensure effective investi...
5 days ago
$66K - $100K *
Drive quality assurance in automated underwriting for Commercial Lines, evaluating system behavior and outcomes. Collaborate with teams to enhance processes, identify trends, and ensure alignment with...
5 days ago
$112K - $137K *
Join a team that's dedicated to optimizing enterprise network infrastructure. This role involves designing, implementing, and maintaining secure, high-performing networks across diverse environments...
5 days ago
Principal Data Center & Cloud Engineering Lead and Strategist
$150K - $180K *
Empower our mission by leading data center and cloud engineering strategies. This hands-on role requires expertise in infrastructure planning, hybrid-cloud architecture, and automation to drive modern...
5 days ago
Account Executive, Solutions (TX)
$80K - $95K *
Elevate educational outcomes by driving new business and customer success in the TX territory. Build trusted relationships with decision-makers while delivering innovative literacy solutions to PreK–1...
5 days ago
AVP of Underwriting - Great American Employer Health Solutions
$150K - $180K *
Lead the charge in underwriting operations and strategy, developing a high-performing team while enhancing practices to support profitable growth in the medical stop loss and level-funded business. Bu...
5 days ago
$77K - $118K *
Elevate project delivery by managing cost and schedule reporting for semiconductor construction projects. Collaborate with cross-functional teams to ensure accurate financial tracking and effective co...
5 days ago
$77K - $118K *
Join a dynamic team to support semiconductor projects by managing cost and schedule reporting. Collaborate with engineering and procurement to ensure accurate project delivery and enhance organization...
5 days ago
$80K - $95K *
Unlock the potential of Workday Financial Management by optimizing processes, enhancing reporting, and collaborating with Finance stakeholders to drive continuous improvement and deliver actionable in...
5 days ago
$114K - $142K *
Drive revenue growth by managing complex agency relationships, mentoring team members, and serving as a trusted advisor. Collaborate cross-functionally to meet agency needs and enhance organizational...
5 days ago
Director of Strategy and Capabilities
$154K - $193K *
Lead strategic initiatives and optimize capabilities to drive growth and value. Collaborate across functions to enhance processes, data, and technology, ensuring alignment with organizational goals an...
5 days ago
$95K - $125K *
Optimize HR excellence in the Midwest by driving talent development, enhancing employee engagement, and supporting General Managers in fostering a high-performance culture. Act as a strategic partner...
Reposted 5 days ago
$75K - $100K *
Transform customer experiences by leading daily operations, ensuring compliance, and empowering team performance in a dynamic collision center environment. Drive success through effective management a...
Reposted 5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.