Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Strategic Account Manager - West Coast
$125K - $150K *
Champion growth by developing new enterprise accounts in Healthcare and Financial Services. Leverage strategic relationships and innovative solutions to drive business value and expand market presence...
Reposted 5 days ago
Relationship Manager, Banking & Treasury Serv
$76K - $85K *
Champion client success by nurturing relationships and driving product adoption. Leverage your expertise to enhance customer satisfaction and retention, while collaborating cross-functionally to ident...
5 days ago
$130K - $160K *
Elevate user experiences by leading design from research to launch, transforming complex workflows into intuitive solutions. Collaborate with cross-functional teams to shape a unified platform that me...
5 days ago
Associate Director, MSL, CMH Cleveland
$156K - $250K *
Champion scientific exchange by leveraging deep expertise to engage with key opinion leaders, providing critical insights and fostering collaborations that shape the future of healthcare and enhance p...
5 days ago
$175K - $195K *
Unlock innovative solutions as a Salesforce Solution Architect, leading design and implementation efforts to meet strategic business needs. Collaborate with stakeholders to deliver maximum value and d...
5 days ago
$160K - $175K *
Elevate platform reliability by designing and evolving cloud infrastructure, CI/CD pipelines, and Kubernetes environments. Collaborate across teams to enhance software delivery, operational excellence...
Reposted 5 days ago
$80K - $95K *
Transform your sales career by driving territory growth and building lasting client relationships. Leverage your expertise in business development to create new opportunities and enhance customer expe...
5 days ago
$80K - $95K *
Elevate your career by owning complex sales cycles in automation solutions. Drive business growth through executive relationships, multi-stakeholder pursuits, and strategic decision-making across dive...
Reposted 5 days ago
Enterprise Account Executive, Acquisition | Central | Remote
$260K - $300K *
Advance your career by driving new business growth through consultative sales. Leverage your technical expertise to engage customers, manage sales processes, and foster strong relationships, ensuring...
5 days ago
Account Executive - Workday Smart Products
$100K - $120K *
Lead business development initiatives by building strategic partnerships and networks. Drive revenue growth through consultative selling and effective stakeholder management while fostering a collabor...
5 days ago
Senior Analyst, Provider and Claim Data & Analytics (Remote)
$88K - $105K *
Analyze complex datasets to drive insights and enhance healthcare analytics. Collaborate with stakeholders to develop reporting solutions, ensuring data integrity and supporting strategic decision-mak...
5 days ago
$120K - $145K *
Transform the engineering landscape by owning architecture, deployment, and incident management. Collaborate with teams to prioritize features, enhance payment systems, and integrate AI, all while ens...
5 days ago
Cultural Resources/Architectural Historian and Senior Project Manager
$135K - $155K *
Join a team that's shaping the future of cultural resources management. As a Senior Project Manager, you'll lead initiatives, mentor staff, and collaborate with experts to enhance our services across...
5 days ago
Senior Staff Software Engineer - Builder Platform
$150K - $180K *
Contribute to the technical leadership of a multi-faceted platform, guiding cross-functional teams in architecting and evolving core engineering tools, AI infrastructure, and workflows to enhance prod...
5 days ago
$95K - $115K *
Champion data-driven decision-making by bridging clinical operations and analytics. Lead projects, deliver actionable insights, and enhance performance across clinics while managing stakeholder commun...
Reposted 5 days ago
Experienced Systems Engineer - Product Owner
$112K - $151K *
Play a key role in the development and integration of cutting-edge systems for aircraft health management. Collaborate with cross-functional teams, manage project budgets, and engage with stakeholders...
Reposted 5 days ago
Software Engineer III (.Net - Full Stack) - REMOTE
$95K - $153K *
Elevate your career by designing and developing secure, scalable .Net applications. Collaborate with cross-functional teams to deliver high-quality solutions while mentoring junior engineers and ensur...
5 days ago
$94K - $157K *
Contribute to groundbreaking advancements in quantum information science by leveraging your expertise in continuous-variable photonics and theoretical algorithm discovery to develop experimental proto...
5 days ago
Software Engineer 5 - Android (DVX Mobile Core)
$388K - $500K+*
Lead the charge in enhancing mobile architecture and quality for Android, driving multi-quarter initiatives that empower engineering teams to innovate and deliver exceptional user experiences at scale...
5 days ago
$160K - $190K *
Transform ambiguity into action by driving strategic initiatives across functions. Collaborate with executives to architect programs that enhance operational efficiency and deliver measurable business...
Reposted 5 days ago
$146K - $190K *
Shape healthcare innovation by building full-stack systems that enhance user experience, drive outcomes, and leverage AI solutions while collaborating across teams to understand business needs and exe...
Reposted 5 days ago
$120K - $145K *
Transform the interaction of mobile robots with their environments by developing cutting-edge learning-based manipulation systems that enhance reliability and safety in dynamic settings, impacting rea...
Reposted 5 days ago
Advanced Practice Nurse - Employee Occupational Health Nurse Practitioner
$90K - $110K *
Unlock potential by providing comprehensive employee health services, focusing on safety, wellness, and disease prevention. Collaborate with teams to enhance health education and ensure a safe work en...
5 days ago
Staff Information Security Engineer
$170K - $220K *
Drive innovation by safeguarding AI systems while implementing robust security measures. Collaborate with diverse teams to ensure efficient AI integration and risk management, balancing security requi...
Reposted 5 days ago
Lead Power Systems Controls Engineer
$97K - $143K *
Empower the future of power systems by developing and implementing innovative control solutions. Collaborate with a skilled team to deliver seamless integration across major OEMs, ensuring optimal per...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.