Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
US National Service Manager - EDAX Products
$115K - $140K *
Drive operational excellence by leading a high-performing field service team, ensuring exceptional customer support and strategic growth while managing complex service challenges and performance metri...
5 days ago
Physician - Sign on Bonus $75,000
$180K - $220K *
Join a dynamic team to provide comprehensive care in a modern urgent care setting. Leverage your expertise to treat diverse patient needs, collaborate with skilled staff, and contribute to quality out...
5 days ago
Physician - Sign on Bonus $75,000
$180K - $220K *
Join a dynamic team to provide comprehensive care in a modern urgent care setting. Lead the charge in delivering quality patient experiences while collaborating with skilled professionals in a support...
5 days ago
Physician - Sign on Bonus $75,000
$210K - $250K *
Drive exceptional patient care by providing comprehensive clinical services in a modern, collaborative environment. Enjoy flexible scheduling and a competitive compensation package while making a diff...
5 days ago
Project Manager - Institutional
$95K - $115K *
Lead the charge in delivering complex healthcare construction projects, ensuring safety, budget adherence, and compliance. Collaborate with multidisciplinary teams to enhance patient care while managi...
Reposted 5 days ago
Partnerships Director - New England
$80K - $95K *
Join a dynamic team focused on transforming early literacy by building partnerships with school leaders. Leverage your educational experience to drive sales and enhance student learning through innova...
Reposted 5 days ago
$100K - $120K *
Join a team that's shaping the future of literacy by building strategic partnerships with school districts. As a key driver of growth, you'll leverage your educational leadership experience to enhance...
Reposted 5 days ago
$150K - $160K *
Unlock potential by designing and optimizing enterprise database environments for mission-critical HRIT applications, ensuring security, scalability, and compliance with federal standards while collab...
5 days ago
$160K - $200K *
Shape your career by leading the delivery of quality medical services and program development while managing a dedicated team of medical professionals to enhance patient care and treatment outcomes...
Reposted 5 days ago
$160K - $200K *
Empower healthcare delivery by guiding medical practice, ensuring quality services, and fostering a collaborative environment. Influence new initiatives while providing clinical consultation and leade...
Reposted 5 days ago
$160K - $200K *
Lead the charge in developing and evaluating a comprehensive medical practice delivery model while ensuring high-quality patient care and collaborating with leadership to innovate service initiatives...
Reposted 5 days ago
Manager, Support Engineering (AMER)
$115K - $194K *
Lead a dynamic Support Engineering team, enhancing customer experiences through AI-driven solutions, mentorship, and scalable processes while fostering a culture of growth and accountability...
Reposted 5 days ago
$100K - $120K *
Join a team that's dedicated to providing comprehensive dental care in an underserved community. Collaborate with healthcare professionals to enhance patient outcomes while making a meaningful impact...
Reposted 5 days ago
$80K *
Empower our operations by leading a dynamic team to ensure timely delivery of medical equipment and services, enhancing patient care through collaboration and strategic oversight in a fast-paced envir...
5 days ago
$180K - $248K *
Advance our product strategy by leading the integration of data center operations into Prism, enhancing diagnostics and decision-making for operators and executives alike. Collaborate with cross-funct...
Reposted 5 days ago
$94K - $169K *
Join a team that's redefining clinical trial monitoring by leading diverse studies, ensuring compliance, and enhancing processes. Collaborate with experts to drive innovation and improve outcomes in a...
5 days ago
$140K - $184K *
Pioneer the development and operational convergence through automation, designing CI/CD pipelines and driving release process efficiency to enhance software delivery across diverse teams and projects...
Reposted 5 days ago
$80K - $95K *
Shape the future of patient care by leveraging your nursing expertise and informatics. Optimize clinical information systems while collaborating with interdisciplinary teams to enhance the overall hea...
Reposted 5 days ago
$80K - $95K *
Lead the charge in managing and selling Table Games and ETGs to casino operators, enhancing customer satisfaction while maintaining strong relationships and achieving sales targets within your territo...
5 days ago
$85K - $115K *
Empower a positive workplace by resolving employment matters, ensuring compliance, and fostering relationships across departments. Collaborate with leaders to uphold ethical standards and promote a cu...
5 days ago
Manager, Technical Assistance Center
$113K - $181K *
Pioneer a high-performing team in delivering impactful technical assistance programs. Lead program managers and specialists to enhance service delivery, operational excellence, and partner satisfactio...
5 days ago
$80K - $95K *
Champion project success by managing healthcare architecture initiatives from inception to completion. Lead diverse teams, engage clients, and ensure compliance with industry standards while deliverin...
5 days ago
Strategic Project Lead - Finance
$100K - $120K *
Elevate your career by leading strategic finance pilots to drive AI model training and evaluation. This hands-on role combines financial expertise and operational leadership to transform emerging proj...
Reposted 5 days ago
Senior Compliance Analyst - Marketplace Compliance
$70K - $126K *
Join a dynamic team to enhance compliance initiatives, manage regulatory reporting, and lead projects. Play a key role in developing policies, conducting audits, and ensuring adherence to state and fe...
Reposted 5 days ago
$103K - $193K *
Drive your career by leading strategic retail media partnerships, leveraging advanced technology to optimize client success and revenue growth. Act as a consultant and SME, guiding brands through the...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.