Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Supervising Process Engineer
$125K - $225K *
Drive innovation and strategic leadership in wastewater treatment and reuse projects, guiding multidisciplinary teams to deliver sustainable, cutting-edge engineering solutions while fostering client...
Reposted 5 days ago
Key Account Manager - Casino Gaming
$100K - $125K *
Grow key accounts in the Casino Gaming sector by driving business expansion, identifying opportunities, and delivering tailored computing solutions. Engage with C-level executives to enhance partnersh...
Reposted 5 days ago
Senior Manager, Revenue Enablement
$185K - $210K *
Develop and lead a high-performing Revenue Enablement team, driving strategic initiatives to enhance sales effectiveness and align enablement programs with evolving business needs in a fast-paced envi...
5 days ago
Principal SAP Plant Maintenance Consultant
$150K - $180K *
Engage in designing and implementing SAP Plant Maintenance solutions for complex federal projects. Collaborate with stakeholders to enhance asset management efficiency and ensure seamless integration...
Reposted 5 days ago
Procedural Services Director at Barnes Jewish Hospital
$110K - $130K *
Drive operational excellence by overseeing clinical, financial, and human resource management across procedural services. Collaborate with diverse teams to enhance service delivery and ensure regulato...
5 days ago
$250K - $300K *
Empower women's health by joining a collaborative OB/GYN practice. Enjoy a four-day work week, mentorship, and a supportive environment while delivering care at a leading medical center. Experience a...
5 days ago
Customer Success Manager (AI Success Architect)
$116K - $148K *
Transform enterprise operations by guiding customers in AI adoption and maximizing Asana's capabilities. Own post-sales relationships, ensuring measurable outcomes and strategic success across a portf...
5 days ago
$137K - $171K *
Drive revenue growth by leading a high-performing sales team focused on expanding existing customer accounts. Collaborate cross-functionally to align strategies and enhance net revenue retention while...
5 days ago
Vascular Access Sales Specialist - Northern Los Angeles and Southern Nevada (Las Vegas)
$100K - $120K *
Join a dynamic team to drive sales in Vascular Access and Blood Collection. Leverage your clinical knowledge and sales experience to build relationships with key decision-makers, ensuring optimal cust...
Reposted 5 days ago
Sr. Project Manager - Industrial Hygiene & Safety Services
$95K - $115K *
Lead the charge in managing complex projects and mentoring teams while ensuring client satisfaction and technical excellence. Drive project success through effective communication and coordination wit...
Reposted 5 days ago
Financial Model Risk Management Lead
$185K - $245K *
Optimize model risk management by validating complex finance and analytics models. Collaborate across teams to identify weaknesses, improve governance, and support model framework implementation. Lead...
Reposted 5 days ago
$95K - $100K *
Optimize enterprise secrets management by implementing and maintaining solutions across multi-cloud environments. Collaborate with teams to integrate security processes, enhance governance, and suppor...
5 days ago
$130K - $150K *
Champion financial excellence as a Controller, leading accounting operations and driving compliance. Collaborate with executive teams, managing audits, reporting, and enhancing operational efficiency...
Reposted 5 days ago
Senior Construction Project Manager
$95K - $115K *
Tackle project management challenges to successfully oversee construction initiatives. Manage planning, scheduling, cost accounting, and quality control while maintaining strong relationships with sta...
Reposted 5 days ago
Acoustics Engineer, Capacity Delivery
$100K - $120K *
Innovate noise control solutions for large-scale AI data centers. Lead acoustic studies, model sound propagation, and recommend effective mitigations while collaborating across engineering teams to en...
Reposted 5 days ago
$190K - $210K *
Explore innovative solutions as you lead the design and architecture of scalable healthcare applications, mentor engineers, and collaborate with cross-functional teams to enhance patient experiences a...
5 days ago
$190K - $220K *
Partner with us to tackle complex engineering challenges, leveraging deep expertise in TypeScript, Postgres, and AWS. Collaborate closely with our VP of Engineering to innovate and deliver impactful p...
Reposted 5 days ago
$100K - $120K *
Transform the future of power delivery by managing complex transmission line projects. Lead teams, ensure quality, and drive project success while collaborating with engineers and stakeholders across...
5 days ago
Sr. Solutions Architect - Technical/Platform
$124K - $187K *
Join a dynamic team to define and guide technical direction across platforms, ensuring scalable, secure solutions that align with business outcomes. Collaborate with cross-functional teams to resolve...
5 days ago
Senior Estimator/Project Manager-Heavy Civil Construction
$100K - $150K *
Join a team that's shaping the future of heavy civil construction by managing complex projects from estimation to execution. Leverage your expertise to deliver high-quality results while collaborating...
Reposted 5 days ago
Internal Audit - Technology Audit & Analytics Advisor - Hybrid
$102K - $170K *
Join a team that's transforming Internal Audit through data analytics and technology. Contribute to innovative audit techniques while collaborating with stakeholders to enhance audit effectiveness and...
5 days ago
VP Sales Industrial Manufacturing
$175K - $210K *
Lead the charge in driving revenue growth by developing and executing innovative sales strategies, managing a high-performance team, and fostering key relationships in the industrial manufacturing sec...
5 days ago
General Manager-Fairfield Columbia, MO
$75K - $90K *
Join us to lead a newly renovated hotel, driving operations, team culture, and guest satisfaction. This role demands a hands-on leader to enhance performance and foster a positive environment while en...
5 days ago
Senior Mainframe z/OS Engineer (Remote/ Work from Home)
$89K - $148K *
Drive the maintenance and enhancement of Mainframe systems, ensuring optimal performance and seamless migrations. Collaborate with a multi-disciplinary team to solve technical challenges and implement...
5 days ago
$134K - $265K *
Lead the charge in architecting and delivering Adobe Commerce solutions, optimizing cloud environments, and enhancing integration capabilities. Drive innovation through serverless extensions and APIs...
Reposted 5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.