Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$350K - $389K *
Transform patient care by providing expert psychiatric services in a supportive, outpatient environment. Collaborate with a dedicated team to enhance mental health outcomes while enjoying a flexible s...
5 days ago
$150K - $170K *
Unlock potential by leading hands-on security engineering efforts to modernize cybersecurity for a major federal agency. Collaborate with teams to remediate vulnerabilities and enhance cloud infrastru...
5 days ago
Business Development Director - Technical Flooring
$125K - $150K *
Lead the charge in driving business development for Technical Flooring, identifying new opportunities, cultivating strategic partnerships, and enhancing client relationships to achieve growth and prof...
5 days ago
Project Engineer - Industrial Water (Kansas City)
$80K - $95K *
Lead the charge in engineering excellence by managing multidisciplinary design efforts, facilitating project success while maintaining utmost quality and compliance. Drive collaboration among teams to...
Reposted 5 days ago
$90K - $110K *
Champion the recruitment process by sourcing top technical talent, collaborating with leadership, and executing full-cycle hiring strategies to meet business objectives in a fast-paced startup environ...
5 days ago
$95K - $115K *
Empower a dynamic team of Project Managers to drive successful product implementations, enhance operational efficiency, and achieve key performance metrics while fostering cross-functional collaborati...
5 days ago
Sage HCM Implementation & Support Manager
$100K - $182K *
Lead client implementations and provide ongoing support for Sage HCM solutions. Guide customers through the full implementation lifecycle, ensuring successful outcomes and optimizing their HCM environ...
5 days ago
Service Excellence Manager - RN (Remote)
$80K - $95K *
Pioneer innovative clinical workflows and enhance service performance in specialty care. Collaborate with stakeholders to implement programs, analyze outcomes, and drive improvements, ensuring excelle...
5 days ago
$175K - $210K *
Join as a strategic leader in Revenue Operations, driving growth initiatives and optimizing performance for a $750M+ Business Unit. Collaborate with executive teams to enhance revenue strategies, fore...
5 days ago
Regional Sales Manager - Western US
$100K - $130K *
Grow your career with an opportunity to drive sales and build client relationships across a diverse territory. Leverage your technical expertise to promote innovative solutions and achieve results, en...
Reposted 5 days ago
Corporate Health and Safety Specialist
$107K - $167K *
Shape the future of health and safety by leading compliance efforts across diverse projects. Collaborate with teams nationwide to ensure safe execution through planning, audits, and site evaluations...
5 days ago
Lead Support Specialist, Digital Banking
$80K - $95K *
Unlock potential by leading a dynamic support team, resolving complex digital banking issues, and enhancing service delivery. Drive operational excellence while mentoring junior specialists and collab...
5 days ago
Vice President - Construction Management (Data Centers)
$170K - $200K *
Unlock potential by overseeing large-scale data center construction projects, ensuring timely delivery, budget adherence, and quality standards while collaborating with diverse stakeholders across all...
5 days ago
Sr. Staff Engineer - Connectors Power BU
$120K - $145K *
Lead product development initiatives by driving innovative solutions in power connectors and cable assemblies. Collaborate cross-functionally to ensure high-quality, cost-effective designs that meet c...
5 days ago
$120K - $145K *
Lead global automation initiatives, driving strategy and execution across manufacturing sites. Oversee teams to enhance productivity, quality, and cost efficiency, focusing on cable assembly operation...
5 days ago
Growth Marketing Manager, Paid Social
$104K - $135K *
Lead the charge in driving strategic growth via innovative Paid Social campaigns across platforms. Own metrics, collaborate cross-functionally, and implement cutting-edge tactics to significantly enha...
Reposted 5 days ago
$115K - $150K *
Innovate your career with a strategic role focused on omnichannel marketing. Lead data-driven insights and creative recommendations for a top financial services brand, collaborating across teams to en...
Reposted 5 days ago
$170K - $200K *
Unlock potential by leading strategic finance initiatives, enhancing planning, forecasting, and reporting processes. Collaborate with executives to drive operational excellence and scale the finance f...
5 days ago
$110K - $150K *
Transform treasury operations by building infrastructure for international and commercial expansion, managing complex cash flows, overseeing debt compliance, and enhancing banking relationships, while...
Reposted 5 days ago
Leadership and Organizational Effectiveness Partner
$98K - $120K *
Unlock potential by designing and delivering impactful leadership programs that enhance employee capabilities and align with business goals. Collaborate with HR and leaders to create effective learnin...
5 days ago
$80K - $108K *
Drive financial excellence by supporting global markets through modeling, forecasting, and analysis. Collaborate with cross-functional teams to enhance business performance and present insights to sen...
5 days ago
Litigation & Compliance Counsel
$163K - $287K *
Lead global litigation management and enhance compliance initiatives while driving strategic legal guidance across pre-litigation matters and ensuring operational alignment with business goals in a dy...
Reposted 5 days ago
Senior Software Development Engineer
$164K - $262K *
Elevate your career by designing and building self-service cloud APIs and services. Collaborate with teams to transform complex cloud operations into reliable, user-friendly products that enhance deve...
5 days ago
Senior Mechanical Engineer 2 - Nuclear
$100K - $152K *
Engineer innovative solutions in nuclear power plant systems design. Collaborate on modification packages, technical specifications, and vendor evaluations while leading project teams to enhance opera...
5 days ago
$120K - $130K *
Elevate content strategy for Cell & Gene Therapy, translating complex science into clear messaging. Lead global campaigns, engage stakeholders, and ensure compliance while driving business growth and...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.