Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$153K - $166K *
Elevate your career as a Senior Engineer, driving governance and compliance in identity management. Collaborate across teams to enhance security and user experience while managing access for human and...
4 days ago
Director, AP Engineering New Course Design
$96K - $135K *
Empower your career by leading the design and development of innovative AP Engineering courses. Collaborate with industry experts to create impactful assessments and instructional resources, ensuring...
4 days ago
Sr Principal Talent Acquisition Business Partner
$106K - $160K *
Deliver strategic talent acquisition solutions by partnering with leaders to enhance hiring processes, drive recruitment strategies, and improve candidate experiences across diverse technical roles in...
4 days ago
Material Rqmnt Planning Analyst
$102K - $153K *
Join a dynamic team as a Material Requirements Planner, where you'll analyze and optimize manufacturing schedules, resolve material issues, and collaborate with cross-functional teams to ensure operat...
4 days ago
Automotive Brand Marketing Manager (Luxury Domestic Brands)
$100K - $162K *
Elevate your career by leading innovative marketing strategies for luxury automotive brands. Collaborate with key stakeholders to drive sales, enhance customer engagement, and optimize performance acr...
4 days ago
Automotive Brand Marketing Manager (Luxury Import Brands)
$100K - $162K *
Transform automotive marketing strategies by leading OEM initiatives that enhance vehicle sales and customer engagement. Collaborate with cross-functional teams to align corporate goals with local mar...
4 days ago
ServiceNow Senior Application Developer
$90K - $189K *
Drive the development and integration of enterprise applications on the ServiceNow platform, focusing on custom solutions and advanced scripting to enhance Configuration Management Database (CMDB) cap...
4 days ago
$98K - $206K *
Drive innovation as a Senior Endpoint Engineer, collaborating with a skilled team to enhance endpoint management and automation, ensuring efficient deployments and robust security for critical systems...
4 days ago
$63K - $129K *
Shape your career by driving Agile execution excellence in federal HCM modernization. Lead cross-functional teams, facilitate SAFe ceremonies, and foster a continuous improvement culture within a larg...
Reposted 4 days ago
$98K - $206K *
Transform your career by joining our team to enhance Microsoft 365 services. Leverage your expertise in Teams, OneDrive, and SharePoint to provide operational support and drive improvements in reliabi...
4 days ago
$75K - $158K *
Empower your career by joining a dynamic team focused on enhancing IT operations. Leverage your expertise in Momentum Financials to drive impactful solutions and collaborate with stakeholders in a hig...
4 days ago
SAP SCM Software Test Engineer
$75K - $158K *
Lead the charge in ensuring system reliability for a mission-critical SAP platform. Collaborate with cross-functional teams to execute manual testing, develop test scripts, and enhance quality assuran...
4 days ago
$82K - $172K *
Elevate your career by leading a dynamic team to enhance engineering management and operational efficiency for key defense contracts, ensuring timely deliverables and client satisfaction while fosteri...
4 days ago
NeoLoad Performance Test Engineer
$75K - $158K *
Elevate your career by joining our team to design and execute performance tests for mission-critical applications, ensuring optimal functionality and scalability in a dynamic Agile environment...
4 days ago
Sr. Business Analyst, Capital One Shopping (Remote-Eligible)
$101K - $115K *
Analyze business challenges and opportunities, driving strategic recommendations through data insights and cross-functional collaboration to enhance product performance and customer experiences...
Reposted 4 days ago
Threat Assessment Manager- GWS Technology & Security Operations (Remote)
$122K - $139K *
Join our team to assess and manage workplace violence threats, ensuring safety and security across corporate and retail environments. Lead initiatives, collaborate with stakeholders, and drive effecti...
4 days ago
Senior Software Engineer – Identity Resolution
$130K - $155K *
Elevate your career by designing and developing high-scale Identity Resolution systems. Collaborate with cross-functional teams to create reliable, secure, and high-performance solutions that link and...
4 days ago
Audience Activation Specialist
$80K - $95K *
Join a team that's redefining acquisition marketing by developing advanced segmentation strategies, optimizing campaigns, and enhancing customer engagement to drive conversion rates and maximize ROI...
4 days ago
$88K - $105K *
Transform clinical trials by leading monitoring efforts, ensuring compliance with protocols and regulations while fostering collaboration and quality improvement across teams and sites...
4 days ago
$100K - $120K *
Optimize clinical trial management by overseeing planning, execution, and compliance. Collaborate with cross-functional teams to ensure data integrity and drive innovative treatments while resolving c...
4 days ago
$92K - $110K *
Transform executive support by managing complex calendars, coordinating board meetings, and ensuring seamless communication. Leverage your expertise to anticipate needs and maintain confidentiality in...
4 days ago
Staff Product Security Engineer
$168K - $269K *
Unlock your potential as a key player in transforming product security. Collaborate with engineering teams to embed security practices, drive risk management, and enhance secure design across applicat...
5 days ago
$78K - $110K *
Unlock potential by leading resource management initiatives to optimize workforce capacity, align talent with project needs, and drive operational excellence. Collaborate with teams to ensure timely s...
5 days ago
Life Sciences Finance Reinvention Partner - Manager
$94K - $293K *
Innovate finance transformation in Life Sciences by advising leadership on end-to-end processes. Leverage expertise in R&D, Commercial, and Supply Chain Finance to modernize operations and drive effic...
5 days ago
New Business Development Director - Healthcare Finance (Oracle / Workday ERP)
$136K - $237K *
Transform healthcare finance by leading ERP sales initiatives, driving new opportunities with Oracle and Workday. Leverage deep industry knowledge to enhance client relationships and deliver innovativ...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.