Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$110K *
Join a dynamic team as you oversee a 3PL distribution warehouse, ensuring safety and efficiency while managing operations, budgets, and staff. Drive excellence in customer service and lead a dedicated...
Reposted 5 days ago
Sr. Product Marketing Manager, Enterprise
$120K - $145K *
Lead and shape the Enterprise narrative, empowering sales and marketing teams with strategic insights and compelling content. Engage complex stakeholders to drive growth and alignment across all custo...
Reposted 5 days ago
$75K - $125K *
Launch your career in law by gaining courtroom experience and managing litigation. Collaborate with a dedicated team, handle new claims, and ensure compliance while supporting the firm's commitment to...
Reposted 5 days ago
$185K - $327K *
Unlock potential by leading security strategy and architecture, partnering with the CISO to enhance technical oversight and incident response. Drive secure practices across teams while mentoring engin...
Reposted 5 days ago
Senior Copywriter, Performance Marketing
$127K - $223K *
Transform the way we communicate life insurance through compelling copy that captures attention and drives action. Collaborate with teams to create impactful Direct Mail and social media content that...
Reposted 5 days ago
Licensed Life Insurance Sales Agent
$70K - $200K *
The Licensed Life Insurance Sales Agent will guide customers through the life insurance buying process, educating them on products and ensuring a transparent experience. This role involves engaging wi...
Reposted 5 days ago
Senior Full-Stack Engineer, Autonomous Defense
$195K - $235K *
Drive innovation in autonomous systems by building robust platforms for AI agents, ensuring seamless execution and user-friendly interfaces while tackling complex distributed systems challenges across...
5 days ago
Staff Product Manager, Tenant Scale
$168K - $285K *
Drive product strategy for tenant scale and unified deployment across platforms, collaborating with engineering and product teams to enhance scalability and customer experience while mentoring peers a...
5 days ago
Strategic Account Executive - Chicago
$114K - $172K *
Drive strategic growth by leading enterprise accounts in Chicago, guiding influential organizations through complex digital transformations with GitLab's AI-powered DevSecOps platform, and building lo...
Reposted 5 days ago
Software Engineer I - Top Secret
$88K - $154K *
Explore a dynamic role in cyber network operations, developing tools that support national security missions. Collaborate with a skilled team to enhance software capabilities and contribute to critica...
5 days ago
Director, Michigan Area Manager
$157K - $283K *
Lead the charge in managing transportation infrastructure projects, ensuring quality and efficiency while driving profitability and collaboration across teams to deliver successful outcomes for client...
Reposted 5 days ago
Project Manager/Program Director, Transportation Engineering
$157K - $283K *
Lead the charge in managing large-scale transportation engineering projects, overseeing all phases from initiation to completion. Leverage your expertise to drive project success and ensure compliance...
5 days ago
$140K - $160K *
Drive the future of financial leadership by managing a dynamic accounting team, overseeing payroll, accounts payable, and general ledger accuracy while ensuring audit readiness and process improvement...
Reposted 5 days ago
Banking Solutions Consultant (Sales Engineer)
$100K - $120K *
Explore innovative banking solutions by bridging technology and business needs. Collaborate with sales and clients to design tailored solutions, ensuring successful adoption of digital banking platfor...
5 days ago
Senior Graphic Designer, Legal Solutions
$88K - $105K *
Elevate brand identity by designing cohesive visual assets and systems. Collaborate cross-functionally to enhance marketing initiatives and ensure brand consistency across all platforms, driving recog...
5 days ago
$120K - $140K *
Join a team that's transforming higher education through ERP solutions. Lead strategy, governance, and optimization initiatives while managing a talented team to enhance operational performance and dr...
Reposted 5 days ago
$113K - $191K *
Empower innovation in safety technology by developing AI-driven solutions that enhance customer experiences and operational efficiency. Collaborate across teams to deliver scalable, impactful products...
Reposted 5 days ago
Leadership Development Manager
$145K - $205K *
Champion leadership growth by designing impactful development programs for new and aspiring leaders. Drive engagement and skill-building through innovative learning experiences that foster high-perfor...
5 days ago
$81K - $99K *
Partner with us to guide new customers through onboarding, ensuring their success with our platforms. Collaborate with teams to develop strategies that enhance client engagement and support throughout...
5 days ago
$87K - $100K *
Unlock potential by leading complex WAN/LAN network solutions, mentoring IT staff, and driving technology decisions to enhance infrastructure security and reliability while tackling challenging techni...
5 days ago
Client Sales Enterprise Account Executive
$110K - $145K *
Empower enterprise growth by managing high-value accounts in a dynamic SaaS environment. Drive the full sales cycle, build executive relationships, and navigate complex negotiations to achieve impactf...
Reposted 5 days ago
Senior Manager, Deal Desk - North America
$153K *
Shape strategic transactions as the Deal Desk lead for North America, collaborating with Sales and cross-functional teams to enhance deal structure, execution, and compliance while optimizing processe...
Reposted 5 days ago
Forward Deployed Product Engineer (Client Facing)
$180K - $220K *
Join a team that's transforming healthcare by integrating innovative solutions with partners. Collaborate closely with technical teams to deliver seamless integrations and enhance user experiences fro...
5 days ago
$160K - $230K *
Join a team that's redefining product engineering by owning high-impact areas from concept to launch. Collaborate closely with leadership to enhance user experiences and drive innovation in a fast-pac...
5 days ago
Senior Manager, BD - Electronic Warfare
$120K - $145K *
Drive strategic business development initiatives in Electronic Warfare, expanding market presence and fostering relationships with US DoD customers. Leverage expertise to identify opportunities, gener...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.