Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Loss Control Consultant II -Kansas City Metro Area (KS or MO)
$61K - $101K *
Join a team that's dedicated to enhancing workplace safety through consultation and training. Evaluate risks, develop loss control strategies, and foster strong relationships with clients to promote e...
3 days ago
Head of Account Management - ISV Platform
$200K - $225K *
Join a dynamic team to drive growth and retention for US ISV partners across payments and money movement. Lead a team of account managers, design strategies, and enhance partner experiences to achieve...
3 days ago
$80K - $95K *
Engineer seamless integrations and automation across systems, enhancing operational efficiency and collaboration. Leverage your expertise in SaaS platforms and APIs to drive innovative solutions in a...
3 days ago
Senior Cost Estimator - Power Generation
$115K - $160K *
Transform project cost management by leading cost estimation and analysis for power generation projects. Drive accuracy at each design gate, ensuring compliance with AACE standards while identifying c...
3 days ago
Sr. Manager, Lifecycle Marketing
$120K - $135K *
Transform the member experience by leading lifecycle marketing strategies that enhance engagement and retention across digital platforms. Drive campaign execution and optimize member journeys using da...
3 days ago
Senior Software Engineer, Containers
$157K - $184K *
Transform the future of container technology by designing and shipping innovative features for Chainguard Containers. Collaborate with a dynamic team to enhance security and performance while directly...
3 days ago
Data Center COE Senior PLC Technician
$83K - $135K *
Lead the charge in delivering expert technical leadership for complex power systems. Oversee startup, commissioning, and maintenance of advanced switchgear and controls, while mentoring junior enginee...
Reposted 3 days ago
Director, Strategic Pricing & Analytics - Health Plan Relations
$125K - $150K *
Shape the future of healthcare pricing analytics by leading payer contract modeling and team development. Utilize your expertise to optimize reimbursement strategies, enhance market intelligence, and...
Reposted 3 days ago
$83K - $125K *
Drive impactful Salesforce solutions by leveraging advanced features and collaborating with teams to enhance system efficiency and user experience. Mentor junior developers while ensuring best practic...
3 days ago
$125K - $150K *
Join a team that's shaping the future of data architecture, integrating innovative solutions across our enterprise ecosystem. Collaborate with diverse stakeholders to optimize and implement robust dat...
Reposted 3 days ago
$70K - $116K *
Lead the cash posting and payment reconciliation for healthcare revenue cycles, ensuring accuracy and compliance. Drive team performance and enhance operational efficiency while managing payer relatio...
3 days ago
Solutions Architect, AI & Automation
$110K - $150K *
Optimize automation initiatives to enhance business efficiency organization-wide. Collaborate with RPA specialists and stakeholders to identify opportunities, design solutions, and drive measurable im...
Reposted 3 days ago
$155K - $185K *
Join a dynamic team to oversee security operations, incident response, and automation initiatives. Collaborate with cross-functional teams to enhance security practices and develop tools that streamli...
Reposted 3 days ago
AI Product Manager, Superhumans & Console
$185K - $260K *
Transform the AI-driven customer experience by leading the Superhuman Console product. Collaborate with cross-functional teams to enhance user engagement, streamline onboarding, and deliver impactful...
3 days ago
$100K - $150K *
Join a team that's dedicated to driving service excellence and profitability through effective management, customer relationships, and operational efficiency in a dynamic environment...
3 days ago
$200K - $275K *
Transform your career by owning the design and delivery of impactful features, collaborating with cross-functional teams to craft innovative software solutions that enhance user experiences and drive...
Reposted 3 days ago
Sr. Federal Business Manager - DoW WEST
$116K - $194K *
Join a team that's driving sales strategies within the Department of War markets. Collaborate with experienced professionals to enhance market share and build relationships with key stakeholders in th...
3 days ago
$80K - $95K *
Join us to streamline customer onboarding, ensuring a smooth transition from sales to production. You'll manage timelines, coordinate approvals, and enhance processes, driving efficiency and satisfact...
3 days ago
Product Strategy & Development Senior Advisor - Express Scripts Pharmacy - Remote
$120K - $145K *
Contribute to innovative product strategies that enhance customer experiences and drive profitable growth in pharmacy solutions. Collaborate across teams to identify market needs, develop business cas...
Reposted 3 days ago
Senior Software Engineer, Data Systems (Python)
$170K - $200K *
Join a dynamic team to design and implement scalable data pipelines, transforming diverse data sources into actionable insights. Collaborate with cross-functional experts to drive innovation and maint...
Reposted 3 days ago
$75K - $100K *
Elevate your career by leading residential capital projects from inception to completion. Collaborate with cross-functional teams to ensure timely, budget-friendly delivery of managed WiFi solutions w...
3 days ago
$151K - $178K *
Lead the charge in operational excellence for strategic partners, managing billing, technical support, and reporting. Collaborate across teams to enhance partner engagement and drive growth through ef...
3 days ago
$146K - $271K *
Drive EHS initiatives across multiple locations, fostering a zero-harm culture while ensuring compliance and sustainability. Collaborate with stakeholders to implement strategic plans and enhance safe...
3 days ago
Principal Technical Consultant, Integrations - State & Local Government
$140K - $210K *
Lead the charge in delivering innovative integration solutions for clients in the State & Local Government sector. Collaborate with project teams to design, develop, and implement effective Workday in...
3 days ago
$95K - $115K *
Champion our event program by strategizing and executing impactful in-person and virtual experiences that drive engagement and measurable results, while managing logistics and cross-functional collabo...
3 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.