Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$110K - $130K *

Drive new business growth by building your own pipeline in a vast territory. Focus on winning new logos through strategic account targeting and disciplined deal management, while collaborating with cr...

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by leading new business acquisition and expansion efforts in a dynamic sales environment. Engage key stakeholders to position solutions that drive scalable growth and manage risk effe...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$225K - $245K *

Lead the charge in shaping analytics for sales and partnerships, driving insights that enhance revenue strategies. Collaborate with executives to translate data into actionable decisions, fostering a...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Business Services

$160K - $200K *

Empower growth by leading demand generation and marketing operations. Drive strategic campaigns, optimize technology stacks, and manage budgets while ensuring brand governance and team development in...

Missouri, USRemote

3 days ago

  •   Less than 5 years exp.  •   Media

$80K - $120K *

Join a team that's dedicated to enhancing educational outcomes for English learners. This role involves consultative sales, relationship building, and managing a full-cycle sales process in the K-12 s...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Drive profitable growth by expanding customer relationships in food, pharmaceutical, and personal care industries. Collaborate cross-functionally to deliver high-quality ingredient solutions and achie...

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$100K - $120K *

Engage with key customers in the food, pharmaceutical, and personal care sectors to drive growth through strategic relationship management and business development. Collaborate cross-functionally to d...

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$108K - $130K *

Drive innovative solutions by applying technical expertise to design and implement seamless overlay management systems that enhance client advisory services, ensuring quality and efficiency across div...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in transforming portfolio execution through strategic initiatives, enhancing governance, and driving measurable outcomes across multiple business areas to deliver lasting value and imp...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's enhancing security across network, cloud, and infrastructure. This hands-on role focuses on implementing and managing security controls, troubleshooting complex issues, and collabor...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$179K - $350K *

Lead the strategy and execution of EMR integrations, enhancing processes and team performance while managing client relationships and driving innovation in healthcare data solutions...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Transform project execution by joining a dynamic engineering team focused on managing supplier subcontracts, ensuring timely delivery, and maintaining quality standards throughout all project phases...

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Redefine regulatory excellence by leading IND/IDE submissions, ensuring compliance, and collaborating with multidisciplinary teams to advance innovative therapies in a remote setting...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Drive enterprise sales success by building a robust pipeline, managing complex deals, and leveraging AI tools to enhance productivity. Collaborate cross-functionally to deliver tailored solutions and...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Join a team that's shaping the future of web and mobile applications. Collaborate with engineers to develop and enhance functionality while managing code and leading process improvements in a dynamic...

3 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$145K - $201K *

Pioneer a robust quality oversight program for unsecured lending, leading end-to-end testing and collaborating across teams to ensure compliance with regulatory standards while driving continuous impr...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$91K - $145K *

Champion third-party risk management by assessing supplier risks, collaborating with stakeholders, and enhancing processes. Drive improvements in frameworks and tools to ensure compliance and operatio...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$185K - $297K *

Lead the execution of innovative onboarding strategies, driving customer success through insights and support resolution. Collaborate with cross-functional teams to enhance product utilization and def...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's shaping the future of employer benefits by driving sales in the Rocky Mountain region. You'll engage with mid-market clients, manage relationships, and contribute to strategic growt...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$91K - $169K *

Champion the growth of enterprise accounts by leveraging performance management solutions. Engage with key stakeholders to drive sales, manage complex cycles, and achieve targets while adapting to mar...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$95K - $115K *

Drive impactful marketing strategies by transforming complex data into actionable insights, collaborating with senior stakeholders, and leading analytical projects from start to finish, all while fost...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Transform geospatial data into actionable insights by leveraging advanced GIS tools and methodologies. Collaborate with teams to enhance mapping products and ensure accuracy in georeferencing, contrib...

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $145K *

Lead the charge in defining and delivering BMS/EPMS systems for high-density data centers, ensuring seamless integration and operational excellence across multiple projects and stakeholders...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $160K *

Architect the future of intelligent K-12 assessment systems by designing a robust knowledge architecture that integrates AI, learning science, and psychometrics. Innovate and build foundational struct...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Accelerate business growth by driving customer acquisition through a consultative sales approach. Leverage your expertise in building relationships and exceeding quotas to deliver exceptional results...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.