Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$100K - $200K *
Transform your career by leading key client relationships, understanding business goals, and driving innovative manufacturing solutions to market. Leverage your expertise to boost sales and collaborat...
Reposted 3 days ago
IT Project Manager - Managed Services Onboarding
$63K - $98K *
Lead the charge in ensuring seamless onboarding for new customers, coordinating efforts across teams to deliver a professional transition from sales to support, while fostering strong relationships an...
3 days ago
Account Executive - Emerging Accounts - Northeast
$75K - $125K *
Empower growth by driving strategic account management and sales initiatives. Collaborate with diverse teams to deliver innovative manufacturing solutions, ensuring client success and exceeding revenu...
Reposted 3 days ago
Manager, Third-Party Risk Management (TPRM)
$164K - $241K *
Lead a global TPRM program, enhancing vendor security risk management through AI-driven workflows and assessments. Manage a team, ensure compliance, and drive risk decisions while collaborating with c...
Reposted 3 days ago
$86K - $138K *
Optimize financial analysis and reporting by conducting in-depth research, preparing forecasts, and collaborating across departments to enhance business outcomes and drive strategic decision-making...
3 days ago
Strategy & Operations Associate, GTM
$100K - $110K *
Join us to drive cross-functional GTM initiatives, enhance operational efficiency, and support executive decision-making. You'll collaborate with teams to align strategies and improve processes, ensur...
3 days ago
Senior Mechanical Engineer - Thermal Solutions
$125K - $137K *
Optimize thermal systems engineering by leading design and performance of skidded equipment for diverse markets. Collaborate across teams to enhance manufacturability and ensure reliable, documented e...
Reposted 3 days ago
Senior Sales Development Representative
$128K - $191K *
Join a team that's driving growth in the CBRNe Safety & Security sector. You'll identify new business opportunities, develop strategies, and manage the sales cycle while collaborating with cross-funct...
3 days ago
Head of Provider Growth Strategy & Operations (Remote)
$135K - $160K *
Elevate your career by leading strategic initiatives that drive provider growth. Collaborate with C-suite leaders to design scalable operations and align cross-functional teams, while mentoring a dedi...
3 days ago
$100K *
Champion exceptional veterinary care by joining a dynamic team focused on exotic and avian medicine. Leverage your skills in a supportive environment that fosters growth, collaboration, and client rel...
3 days ago
Full Stack Developer - IT Service Delivery
$82K - $123K *
Transform your career by joining a dynamic team focused on innovative full stack development, integrating AI capabilities, and delivering robust solutions for diverse business needs. Collaborate with...
Reposted 3 days ago
Lead Specialist, Learning Scientist (Clinical)
$95K - $115K *
Champion innovative research in clinical assessments, leading product development and strategy across multiple domains. Collaborate with cross-functional teams to translate scientific evidence into im...
3 days ago
$280K - $330K *
Empower a dynamic engineering team by leading technical architecture, enhancing system reliability, and driving scalable solutions that support rapid growth in a fast-paced fintech environment. Foster...
Reposted 3 days ago
$160K - $180K *
Drive growth and satisfaction by managing client relationships in Life Sciences. Oversee the sales process, collaborate with experts, and leverage insights to uncover new opportunities while ensuring...
3 days ago
Director, Media Engagement (Consumer Media & Programs)
$155K - $170K *
Transform the national media landscape by leading strategic communications initiatives that elevate awareness of Alzheimer’s disease and dementia. Collaborate with executive leadership to drive impact...
3 days ago
$80K - $95K *
Accelerate fundraising efforts by managing a diverse portfolio of major gift prospects, cultivating relationships, and securing transformative donations to support a national mission focused on ending...
Reposted 3 days ago
Senior Software Engineer, Identity & Regulatory Platform
$135K - $160K *
Lead the development of AI-driven systems for onboarding and compliance, enhancing customer journeys for major financial institutions. Collaborate with cross-functional teams to optimize processes and...
3 days ago
$80K - $85K *
Drive your career forward by managing operations that boost sales, profitability, and customer satisfaction. Lead a dynamic team, oversee financial management, and develop strategic plans to enhance m...
Reposted 3 days ago
Senior Manager, Software Development Engineering
$106K - $284K *
Elevate your career by leading a dynamic engineering team to build scalable, cloud-native solutions within the Salesforce ecosystem, driving innovation across key business areas like Marketing, Sales...
Reposted 3 days ago
Senior Render Engineer: Rendering / Metal / DirectX / OpenGL / FFmpeg
$120K - $145K *
Lead the charge in optimizing our rendering system, enhancing performance and user experience across cutting-edge video technologies. Collaborate with a dynamic team to push the boundaries of audio an...
3 days ago
Staff, Technical Account Manager
$116K - $171K *
Join a team that's dedicated to delivering exceptional technical support to strategic customers. Leverage your expertise to resolve complex issues, enhance customer experiences, and drive improvements...
3 days ago
$153K - $226K *
Advance your career by owning and evolving our Workday platform, focusing on payroll and Core HCM. Collaborate with cross-functional teams to design scalable systems that enhance operational efficienc...
3 days ago
$135K - $160K *
Drive impactful data science initiatives by leading a high-performing team, fostering collaboration, and ensuring effective delivery of analytics solutions that create measurable business value and pr...
3 days ago
Senior Software Engineer, Accounts
$145K - $193K *
Architect and enhance robust software solutions for player registration, identity verification, and compliance. Collaborate across teams to optimize performance, scalability, and security while mentor...
Reposted 3 days ago
$140K - $185K *
Inspire the evolution of a brand by leading innovative design for campaigns and web experiences. Collaborate across teams to develop scalable brand systems, mentor creatives, and direct impactful stor...
Reposted 3 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.