Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$85K - $90K *
Unlock potential by leading a dynamic Customer Success team to enhance client satisfaction, drive product adoption, and identify upselling opportunities, ensuring customers achieve their business goal...
3 days ago
Corporate Account Executive - California
$125K *
Empower your sales career by driving growth in the SaaS/Security sector. Build relationships with key decision-makers, exceed quotas, and collaborate across teams to deliver exceptional value and solu...
3 days ago
$112K - $140K *
Transform the future of software development by architecting and enhancing back-end solutions across diverse applications, mentoring engineers, and driving Agile processes to deliver high-quality soft...
3 days ago
$75K - $95K *
Join a team that's dedicated to delivering impactful user events across North America and Europe. You'll manage logistics, coordinate teams, and ensure engaging experiences that drive product adoption...
3 days ago
$200K - $232K *
Lead the charge in shaping innovative educational products for universities, enhancing faculty engagement and institutional adoption through AI-driven solutions and comprehensive support, while drivin...
3 days ago
$108K - $155K *
Elevate your career by leading complex public sector deployments, ensuring seamless execution of Zero Trust solutions while collaborating with cross-functional teams to achieve impactful business outc...
3 days ago
Senior Product Manager, GRC Platform
$135K - $160K *
Transform core GRC platform capabilities into intelligent, agentic experiences. Own the product strategy, engage with stakeholders, and redefine user workflows while enhancing automation and flexibili...
Reposted 3 days ago
Remote Clinical Psychologist - Older Adults (PhD, PsyD)
$80K - $100K *
Advance your career by providing telehealth psychotherapy to older adults. Enjoy flexible scheduling, a supportive team, and a full caseload tailored to your availability. Focus on meaningful work wit...
3 days ago
Senior Cost Manager / Quantity Surveyor - Data Center Construction
$100K - $120K *
Explore a pivotal role in delivering high-value cost management services for a large-scale data center program, ensuring accuracy and consistency across multiple phases while leading client interactio...
3 days ago
$9K - $185K *
Lead the optimization of large-scale SQL Server databases, enhancing performance and efficiency. Drive data mining capabilities by resolving bottlenecks and implementing innovative solutions that dire...
3 days ago
RN Manager Cardiac Specialty Unit
$80K - $95K *
Transform patient care by leading the Cardiovascular Telemetry department, ensuring high-quality nursing practices, resource management, and exceptional clinical outcomes while fostering a supportive...
3 days ago
Partner Product Marketing Manager
$110K - $130K *
Help us shape the future of partner marketing by crafting compelling narratives that drive adoption and engagement for our Buyer Intent product line, collaborating with cross-functional teams to deliv...
3 days ago
Vice President, New Enterprise Growth - Remote United States
$150K - $180K *
Unlock new business opportunities by driving sales growth in emerging healthcare markets. This role focuses on building relationships with non-national health plans and technology partners, achieving...
3 days ago
Vulnerability Management Engineer
$130K - $140K *
Join a dynamic team as a Tenable Administrator, managing endpoint security platforms. Leverage your expertise in Linux and vulnerability management to enhance security protocols and support our Intell...
3 days ago
MQ-25 Vehicle Management System (VMS) Software Lead Engineer
$198K - $267K *
Unlock potential by leading the development of complex software systems for cutting-edge unmanned aircraft. Collaborate with a team of engineers to create real-time embedded solutions that enhance ope...
Reposted 3 days ago
Customer Success Manager - Enterprise
$106K - $177K *
Shape customer success by managing enterprise accounts, driving satisfaction and retention through strategic guidance, proactive support, and relationship building. Collaborate with sales teams to max...
3 days ago
Manager of Customer Success (Remote, US)
$110K - $130K *
Transform customer success at a strategic level by leading a diverse team of CSMs, driving initiatives to enhance satisfaction, retention, and growth while collaborating across departments to align wi...
3 days ago
$61K - $102K *
Transform customer relationships by managing a high-volume portfolio, driving renewals, upsell, and cross-sell opportunities while ensuring exceptional engagement and retention across North America...
3 days ago
Client Success Manager - Business & Government
$79K - $98K *
Empower customer success by fostering relationships and driving value through strategic engagement and support. Collaborate cross-functionally to enhance customer satisfaction and retention while iden...
3 days ago
Digital Primary Care Physician (Pacific Time Zone, Evenings)
$291K - $312K *
Shape the future of primary care by delivering compassionate, evidence-based treatment through innovative digital platforms, collaborating with a diverse team to enhance patient outcomes and foster in...
3 days ago
$181K - $232K *
Lead product innovation and streamline customer migration to flagship platform, leveraging advanced technical skills to design scalable, secure applications and enhance user experiences through effect...
3 days ago
Generalist Builder-in-Residence
$100K - $120K *
Shape the future of startups by driving high-impact initiatives across multiple portfolio companies. Engage directly with founders to tackle critical challenges, scale operations, and explore new busi...
Reposted 3 days ago
Senior Data Scientist, Hardware Quality
$172K - $203K *
Tackle complex reliability challenges in consumer hardware by building data-driven models and systems. Collaborate cross-functionally to enhance product quality and performance, leveraging advanced an...
3 days ago
$110K - $130K *
Empower teams by translating complex data into actionable insights, guiding strategic financial modeling, and enhancing decision-making processes for portfolio companies through collaborative relation...
3 days ago
Director, Process Excellence - Health Systems
$119K - $186K *
Lead transformative process improvements by leveraging customer insights to enhance operational excellence across Health Systems & Government Services, ensuring scalable, customer-centered execution a...
3 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.