Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Lead Project Manager, Equitable Electric Mobility
$93K - $106K *
Lead impactful initiatives in equitable electric mobility, managing multi-state programs and fostering collaboration among diverse stakeholders to drive sustainable transportation policies and practic...
Reposted 2 days ago
Sr. Account Executive - Express Scripts - ENCORE
$110K - $130K *
Play a key role in nurturing client relationships and driving account strategies to enhance customer satisfaction and retention, while identifying growth opportunities to achieve corporate objectives...
Reposted 2 days ago
Manager of Medicare Advantage and Commercial Revenue
$88K - $105K *
Drive the future of revenue cycle management by leading a dynamic team, overseeing compliance, audits, and financial reporting while serving as a key liaison for internal and external stakeholders...
2 days ago
Technical Customer Success Manager
$95K - $115K *
Join a team that's dedicated to enhancing customer success through technical guidance and relationship management. You'll oversee onboarding, advocate for clients, and drive product adoption while col...
2 days ago
SAP IS-U FICA Consultant - Utilities
$59K - $177K *
Drive transformation in utility financial operations by leveraging SAP IS-U FICA expertise. Collaborate with stakeholders to enhance customer accounting, payment processing, and collections, ensuring...
2 days ago
SAP Finance Architect/Senior Manager - Retail
$132K - $338K *
Champion innovative SAP Finance solutions in retail, guiding clients through full-cycle transformations. Leverage deep expertise in SAP S/4HANA, CAR, and POSDTA to architect seamless integrations and...
2 days ago
Director - Enterprise Learning
$125K - $150K *
Partner with us to lead and innovate learning strategies that enhance advisor and branch team performance, driving measurable business growth through scalable solutions and effective capability develo...
2 days ago
SAP Product Costing Senior Manager - CMT (Software & Platforms)
$112K - $338K *
Empower clients by leading SAP Finance Transformation projects that drive innovation and business value. Collaborate with senior executives to architect solutions, leveraging AI and best practices to...
2 days ago
Oracle Finance Solution Architect, Senior Manager
$122K - $338K *
Transform enterprises by architecting Oracle solutions that enhance business operations. Lead design sessions, develop strategies, and foster client relationships to deliver measurable value across va...
2 days ago
$138K - $163K *
Lead and inspire software engineering teams to deliver innovative solutions, ensuring high-quality standards and alignment with business goals. Foster a collaborative culture while driving continuous...
2 days ago
Medical Science Liaison (New England)
$120K - $145K *
Join a team that's dedicated to advancing hematology/oncology by providing expert medical insights and fostering relationships with healthcare professionals. This field-based role supports product uti...
2 days ago
Director, Business Development
$160K - $329K *
Explore a pivotal role in driving business development strategies that enhance the impact of innovative technologies in the life sciences sector. Collaborate with industry partners to translate resear...
2 days ago
Guest Relations & Concierge Manager
$95K - $110K *
Transform guest experiences by leading and developing a dynamic Concierge team, ensuring exceptional service delivery and operational excellence across multiple time zones while driving revenue growth...
2 days ago
Midwest Surface Water Practice Lead
$192K - $313K *
Champion the growth of our Midwest Surface Water practice by leading teams, enhancing technical capabilities, and fostering client relationships to drive sustainable business development and project e...
Reposted 2 days ago
Midwest Surface Water Practice Lead
$192K - $313K *
Help us lead and grow our Midwest Surface Water practice by mentoring talent, enhancing technical capabilities, and driving strategic business development to meet diverse client needs in water resourc...
Reposted 2 days ago
Physician-Remote Diagnostic Radiologist (Recruitment/Relocation Authorized)
$210K - $250K *
Champion the future of radiology by providing diagnostic services and consultations to Veterans. Collaborate with multidisciplinary teams, ensure quality care, and engage in academic responsibilities...
2 days ago
Director of Global Field Operations
$160K - $200K *
Strategize and enhance global field operations by diagnosing execution gaps, designing scalable models, and driving AI-enabled insights to optimize sales performance and accountability across teams, e...
2 days ago
$89K - $150K *
Transform sourcing strategies to optimize cost, quality, and risk while managing competitive events and stakeholder partnerships. Drive process improvements and digital transformation in sourcing and...
2 days ago
Senior Manager, Clinical Quality Assurance (Remote)
$140K - $180K *
Shape the future of clinical quality assurance by overseeing trials, ensuring compliance with GCP and ICH standards, and driving operational excellence across clinical activities within a cross-functi...
Reposted 2 days ago
$115K - $140K *
Elevate your career by managing day-to-day accounting operations, ensuring compliance with U.S. GAAP, and collaborating across departments to support financial reporting and audits in a dynamic pharma...
Reposted 2 days ago
$100K - $120K *
Unlock potential by driving sales in the employer benefits space, managing relationships, and closing deals in Texas and Oklahoma. Collaborate with teams to shape growth and ensure successful implemen...
2 days ago
$115K - $145K *
Advance your career by managing district relationships and ensuring exceptional service delivery. Collaborate with operations to resolve issues, present performance metrics, and drive customer satisfa...
2 days ago
HVAC Application Specialist - Southern California
$95K - $105K *
Drive your career with a key role in supporting retrofit sales through strategic technical field support, optimizing HVAC systems, and enhancing customer engagement across a regional territory...
Reposted 2 days ago
Director of Information Technology (IT)
$125K - $150K *
Transform technology strategy across a dynamic manufacturing organization. Lead initiatives in cybersecurity, infrastructure, and digital transformation while aligning IT investments with business goa...
2 days ago
VP, Strategic Growth Executive
$130K - $165K *
Drive strategic growth by acquiring new logos and expanding partnerships within large health systems. Navigate complex sales cycles, build executive relationships, and enhance enterprise value through...
2 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.