Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$75K - $120K *

Join a team that's dedicated to driving growth in retirement solutions. Lead and develop a sales team, enhance client relationships, and execute strategies to achieve revenue goals while navigating in...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Join a team that's redefining event strategy! Lead national programs, manage budgets, and drive demand generation through impactful events. Collaborate with executives to enhance marketing efforts and...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $160K *

Support the delivery of MR education and training across various healthcare settings. Collaborate with teams to ensure site readiness and enhance the learner experience while traveling extensively thr...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Champion client relationships by providing consultative support and strategic solutions. Drive retention and satisfaction for elite advisor plan clients through proactive engagement and collaboration...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$72K - $141K *

Lead the charge in driving transformative operational initiatives through generative AI solutions. Collaborate with diverse stakeholders to translate needs into actionable requirements, ensuring effec...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$70K - $90K *

Empower clients by managing habitational commercial insurance accounts, fostering relationships, and ensuring seamless service delivery. Collaborate with team members to strategize on complex coverage...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Join a team that's dedicated to enhancing employee experience and operational efficiency. Collaborate with leaders to drive performance management, employee relations, and people programs, ensuring a...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K *

Unlock potential by delivering exceptional physical therapy services across multiple states. Engage in 13-week assignments at various outpatient clinics, enjoying professional support and comprehensiv...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$168K - $231K *

Analyze financial data and trends to guide strategic decisions, manage budgets, and lead a team in enhancing performance. Collaborate with executives to develop long-term plans and improve organizatio...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $105K *

Lead the efficient execution of construction projects, overseeing field labor and subcontractors while ensuring safety and quality standards are met. Manage project logistics and foster strong relatio...

2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$147K - $205K *

Innovate with us to lead global Technical Support Engineering operations, enhancing customer experience through effective problem-solving, operational excellence, and team development. Drive continuou...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Engineer seamless digital banking solutions by leading technical implementations, collaborating with clients, and ensuring successful project delivery from kickoff to launch while enhancing best pract...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $152K *

Transform project management by leading medium to large-scale E,F&I projects. Drive customer satisfaction and achieve financial targets while collaborating with cross-functional teams to ensure qualit...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$120K - $145K *

Champion innovative AI solutions by leading the design and implementation of enterprise-scale AI Agent systems. Collaborate with teams to integrate Dynamics 365 and Azure services, ensuring compliance...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in driving new business growth by identifying prospects, building strategic relationships, and expanding market presence. Collaborate with internal teams to deliver customer-focused so...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Transportation

$120K - $145K *

Drive innovation by designing async backend systems that integrate AI seamlessly, enabling scalable solutions for millions of businesses. Collaborate with a dynamic team to transform concepts into pro...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Empower your career by leading a dynamic team in fleet sales. Drive performance, enhance cross-functional relationships, and shape sales strategies to achieve growth and operational excellence in a fa...

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$83K - $133K *

Join a team that's driving sales of electrification products, focusing on customer relationships and market growth. Leverage your expertise to identify new opportunities and achieve sales targets in t...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead account management initiatives by developing strategic relationships, driving sales growth, and delivering tailored technology solutions that meet client needs while achieving personal and compan...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$195K - $245K *

Join a team that's redefining partner management by owning high-value relationships, driving growth through strategic planning, and collaborating across departments to enhance customer outcomes and re...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$71K - $106K *

Lead clinical patient care by assessing needs, coordinating staffing, and ensuring quality outcomes. Collaborate with healthcare teams to enhance patient experiences and maintain safety standards in a...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K *

Lead the integration of acquired businesses, ensuring seamless transitions and customer satisfaction while managing project plans, risks, and cross-functional collaboration for successful outcomes...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$97K - $194K *

Empower your career by driving innovative sales strategies in employee benefits. Engage with clients, manage complex accounts, and leverage technology to enhance service delivery while achieving sales...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$205K - $242K *

Champion innovative creative operations by managing design talent and projects. Collaborate with cross-functional teams to deliver high-quality work for world-class brands, ensuring efficiency and exc...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the charge in managing full construction lifecycles, ensuring seamless project execution while collaborating with diverse teams to uphold safety and quality standards in healthcare environments...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.