Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$95K - $193K *
Elevate Paid Media strategies across a diverse portfolio, ensuring alignment with digital marketing goals. Lead investment management, agency collaboration, and performance oversight to drive impactfu...
Yesterday
$110K - $130K *
Innovate and lead full-stack application development across diverse sectors, ensuring secure, scalable solutions. Collaborate with teams to transform concepts into market-ready products while establis...
Yesterday
Certification Authority Administrator, Leo Trust Services
$119K - $208K *
Explore an opportunity to lead security initiatives for a satellite broadband project. Drive the design and operation of PKI systems, ensuring compliance and security while collaborating with diverse...
Reposted yesterday
Territory Sales Manager - Midwest
$80K - $95K *
Lead the charge in driving growth within the territory by building strong customer relationships, expanding key accounts, and delivering tailored water treatment solutions to meet complex challenges i...
Yesterday
Senior Manager, Identity and Access Management
$130K - $155K *
Innovate and lead the development of a comprehensive IAM program, collaborating across teams to enhance identity governance and security. Manage a skilled team while ensuring compliance and effective...
Yesterday
$120K - $145K *
Elevate project delivery by managing multiple concurrent engagements, ensuring timely execution and quality. Collaborate with teams to drive client satisfaction and optimize resources while maintainin...
Yesterday
$108K - $140K *
Unlock potential by leading verification and validation for regulated medical device software. Collaborate with cross-functional teams to ensure compliance and quality in bioinformatics and lab automa...
Yesterday
$90K - $120K *
Transform your career by modernizing legacy applications and integrating AI solutions. Collaborate with cross-functional teams to design, develop, and enhance software that boosts efficiency and drive...
Yesterday
$84K - $105K *
Engage with a dynamic Inside Sales Team, driving strategies to enhance customer acquisition and retention. Lead initiatives that maximize sales revenue and market share while fostering collaboration w...
Yesterday
Field Sales Representative - Excavation
$80K - $100K *
Champion exceptional sales strategies by engaging with pre-qualified leads, conducting assessments, and delivering tailored sewer line solutions for residential and commercial clients, all while enjoy...
Yesterday
Senior Implementation Consultant, Logis Dispatch
$95K - $115K *
Lead complex Logis Dispatch implementations from kickoff to handoff, ensuring dispatch centers go live smoothly. Collaborate with teams to configure systems, train users, and mentor consultants while...
Yesterday
Director, Strategic Partnerships
$150K - $170K *
Drive strategic partnerships by leading growth initiatives, enhancing partner relationships, and executing annual strategies. Collaborate cross-functionally to optimize performance, improve satisfacti...
Yesterday
Dassian CLM Functional Consultant
$100K - $120K *
Shape the future of contract management in aerospace and defense. Leverage your expertise in Dassian and SAP S/4HANA to enhance contract lifecycle processes, ensuring compliance and efficiency in gove...
Yesterday
Senior Staff Software Engineer, Android & IoT
$144K - $220K *
Drive technical excellence as a Senior Staff Engineer, leading the Ops Portal team in shaping architecture and product direction across multiple platforms, while ensuring robust, scalable solutions fo...
Yesterday
$69K - $119K *
Elevate your career by managing diverse projects in healthcare, ensuring timely delivery and quality. Collaborate with teams to implement best practices, drive innovation, and enhance client experienc...
Yesterday
Senior Foundry Integration Engineer
$126K - $173K *
Drive integration strategies to enhance silicon photonic fabrication, collaborating with foundries to evolve processes from development to production while ensuring robust performance and reproducibil...
Reposted yesterday
Marketing Manager - Pursuit Excellence
$88K - $105K *
Drive marketing excellence by leading pursuit strategies, enhancing client engagement, and optimizing proposal processes. Collaborate cross-functionally to implement best practices and elevate brand p...
Yesterday
Senior Business Intelligence Analyst - AI & Automation
$85K - $95K *
Champion data-driven insights by modernizing analytics through AI automation. Leverage SQL and BI tools to transform complex data into actionable reports, ensuring clarity and accuracy for leadership...
Yesterday
Director of Organizational Operations
$80K - $95K *
Drive operational excellence by leading grants management, compliance, and program evaluation. Oversee data systems and risk prevention while ensuring accountability and stewardship of resources to su...
Yesterday
$175K - $200K *
Join a dynamic team to manage strategic supplier partnerships, ensuring alignment with growth objectives and operational needs in a fast-paced cloud infrastructure environment. Drive collaboration and...
Yesterday
Senior Brand Experience Strategist
$95K - $115K *
Shape impactful brand experiences by integrating audience insights into creative campaigns. Collaborate with cross-functional teams to enhance workflows using generative AI tools, ensuring consistency...
Yesterday
$80K - $95K *
Join a team that's dedicated to enhancing clinical imaging support by providing expert troubleshooting and proactive solutions to ensure seamless operations for radiologists and clinical staff...
Yesterday
AVP-Acute Care Pharmacy Operations
$222K - $299K *
Grow your career with a leadership role overseeing national acute care pharmacy operations, driving standardization and continuous improvement across 90 hospitals while developing pharmacy talent and...
Yesterday
$188K - $235K *
Grow your career with a hands-on leadership role in GTM analytics, driving data-driven decisions across Sales, Marketing, and Customer Success. Shape analytics products and insights to enhance pipelin...
Yesterday
Senior Penetration Tester & Cyber Compliance Consultant
$94K - $146K *
Transform cybersecurity by leading comprehensive penetration testing engagements, identifying vulnerabilities, and delivering actionable insights to clients while mentoring junior talent and advancing...
Yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.