Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$100K - $129K *
Drive your career with a Senior Network Administrator role, managing and optimizing enterprise network infrastructure. Collaborate across teams to ensure security, performance, and scalability while l...
Reposted yesterday
$103K - $146K *
Join a team that's driving innovation in construction management. Oversee project profitability and success from estimates to completion, ensuring quality and timely delivery while fostering strong re...
Yesterday
Lead Specialist, PRC Operations
$66K - $127K *
Shape the future of pharmaceutical marketing by leading PRC operations, ensuring compliance, and driving process improvements. Collaborate cross-functionally to enhance promotional material review and...
Yesterday
$185K *
Drive growth by leading a team of Strategic Account Managers to enhance enterprise account value through cross-sell and upsell strategies, fostering executive relationships and achieving expansion goa...
Yesterday
$75K - $90K *
Optimize sourcing strategies and supplier relationships to drive value across regions. Lead negotiations, manage contracts, and collaborate with stakeholders to enhance procurement processes and maxim...
Yesterday
Financial Analyst- Pricing & FP&A
$80K - $95K *
Shape the future of financial analysis by providing critical insights into pricing, profitability, and forecasting. Collaborate with cross-functional teams to enhance decision-making and drive busines...
Yesterday
Advanced Technical Support Specialist
$74K - $112K *
Empower your career with a pivotal role in technical support, delivering expert troubleshooting for gas engine systems. Collaborate globally to resolve issues, enhance customer satisfaction, and drive...
Yesterday
Vice President, Commercial Real Estate
$150K - $180K *
Empower growth by managing commercial real estate loans, analyzing financials, and fostering client relationships. Lead a team to ensure compliance and optimize portfolio performance while collaborati...
Yesterday
Director of Corporate and Foundation Relations
$80K - $95K *
Lead fundraising initiatives by developing strategic partnerships with corporations and foundations. Cultivate donor relationships, manage proposals, and drive philanthropic support to align with the...
Yesterday
Senior Product Manager, International Platform and Globalization
$137K - $186K *
Unlock potential by leading cross-functional teams to deliver platform features that enhance global market capabilities. Drive localization efforts and ensure seamless integration across diverse regio...
Yesterday
Lead Transmission Line Engineer
$92K - $166K *
Join a team that's shaping the future of electric transmission design. Lead and mentor engineers while managing complex projects for major utilities. Drive innovation and quality in a dynamic, remote...
Yesterday
Senior Director - Portfolio Risk & Underwriting Strategy
$137K - $210K *
Lead the profitability and risk strategy for a diverse Asset Protection portfolio. Shape underwriting governance and drive data-informed decisions to enhance product performance across multiple market...
Yesterday
$76K - $139K *
Join a team that's dedicated to designing innovative mechanical systems for healthcare and critical facilities. Collaborate with multidisciplinary teams to deliver high-performance solutions while adv...
Yesterday
$110K - $130K *
Empower our team by designing innovative solution architectures that align with business needs. Collaborate with stakeholders to assess requirements, conduct fit-gap analyses, and develop implementati...
Yesterday
Medical Director Aetna Duals Center of Excellence
$174K - $374K *
Empower healthcare delivery by leading utilization management and appeals processes. Collaborate with a centralized team to ensure timely responses for members and providers, enhancing the quality of...
Yesterday
$85K - $102K *
Reimagine project management as you lead diverse MEP design operations, ensuring quality, timely delivery, and strong client relations across multiple sectors. Drive team performance while fostering p...
Reposted yesterday
Senior Network Load Balancing Architect
$120K - $145K *
Transform the future of application delivery by leading architecture and strategy for enterprise load balancing across hybrid and cloud environments, ensuring optimal performance and resiliency while...
Yesterday
Senior Network Security Engineer
$110K - $130K *
Lead the charge in enhancing our security landscape through policy optimization, automation, and operational improvements across key platforms, while serving as the senior technical expert for complex...
Yesterday
$80K - $95K *
Lead the charge in transforming healthcare insights into impactful creative campaigns, collaborating with cross-functional teams to design patient-centered solutions and integrating modern tools for e...
Yesterday
$80K - $95K *
Empower reimbursement systems by developing and managing third-party calculations, preparing cost reports, and leading cross-functional teams to enhance net revenue management and compliance...
Yesterday
Director- Allied Health Programs
$80K - $90K *
Elevate healthcare education by leading the development of innovative allied health programs. Drive growth and improvement through strategic partnerships, curriculum design, and compliance, ensuring l...
Reposted yesterday
$125K - $150K *
Accelerate growth by driving revenue through strategic sales of a digital payment platform to insurance carriers. Engage with C-level executives to foster relationships that enhance long-term success...
Reposted yesterday
SAP S/4 Record-to-Report (R2R) Consultant - Utilities
$59K - $177K *
Empower finance transformation by leading SAP S/4HANA initiatives, optimizing Record-to-Report processes, and collaborating with cross-functional teams to enhance financial operations and reporting in...
Yesterday
Safety and Occupational Health Specialist
$91K - $119K *
Analyze and manage safety protocols for ammunition and explosives, ensuring compliance and risk mitigation across various contractor operations. Collaborate with stakeholders to enhance safety measure...
Yesterday
Safety and Occupational Health Specialist
$90K - $118K *
Lead the charge in ensuring safety and compliance in ammunition and explosives operations. Oversee risk management and collaborate with contractors to enhance safety protocols, while providing expert...
Yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.