Find $100K+ Jobs in Michigan

Explore professional opportunities in Michigan with salaries of $100,000 or more. From Detroit and Grand Rapids to Ann Arbor, Lansing, and communities across the state, Ladders helps experienced professionals discover vetted roles with competitive compensation.

Explore Michigan Opportunities Across Industries

Michigan’s economy spans automotive and advanced manufacturing, healthcare, technology, finance, education, energy, and professional services. Browse senior-level and specialized openings that match your experience, skills, and career goals.

Search by Location and Career Goals

Find opportunities in major employment centers such as Detroit, Ann Arbor, Grand Rapids, and Lansing, or consider roles elsewhere in Michigan. Compare positions by responsibilities, location, work arrangement, and compensation to focus your search.

Advance Your Career with Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more. Create a profile, refine your search, and explore Michigan roles that align with your expertise and next career move. Job availability and compensation vary by employer and position.

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1,000+

Jobs in Michigan

Average Salary in USD

Average Salary: $127,832

Sort By: Relevance

$67K - $101K *

Empower patient care operations by overseeing home health services, ensuring compliance with regulations, enhancing profitability, and leading a qualified team to deliver high-quality care while achie...

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  •   Less than 5 years exp.  •   Healthcare

$115K - $130K *

Drive marketing measurement innovation by developing scalable frameworks and advanced analytics. Collaborate across teams to enhance performance tracking, optimize investment strategies, and deliver a...

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  •   5 - 7 years exp.  •   Healthcare

$119K - $180K *

Optimize SAP environments by administering, monitoring, and supporting SAP S/4HANA and related technologies. Collaborate with cross-functional teams to ensure a secure, high-performing system that mee...

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  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Champion your career by leading security engagements, assessing architectures, and enhancing compliance. Collaborate with top professionals to identify risks and implement best practices, ensuring rob...

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  •   5 - 7 years exp.  •   Information Technology

$139K - $235K *

Transform compensation strategies by leading program design and execution. Collaborate with cross-functional teams to ensure compliance, enhance processes, and deliver accurate outcomes that attract a...

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  •   5 - 7 years exp.  •   Information Technology

$300K - $350K *

Join a team that's driving sales growth in the cybersecurity sector. This role focuses on acquiring new accounts, building customer relationships, and ensuring satisfaction while exceeding sales quota...

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  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Engineer secure identity solutions across Okta, Microsoft Entra ID, and Active Directory. Collaborate with teams to enhance authentication, lifecycle management, and access governance while implementi...

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  •   5 - 7 years exp.  •   Technical Services

$90K - $110K *

Join a team that's dedicated to enhancing information security through proactive assessments and innovative solutions. Contribute to compliance and risk management while implementing best practices in...

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  •   Less than 5 years exp.  •   Business Services

$138K - $165K *

Lead the charge in designing and deploying cutting-edge LLM applications that solve real user challenges. Drive the full AI development lifecycle, ensuring quality and scalability while transforming i...

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  •   Less than 5 years exp.  •   Information Technology

$150K - $200K *

Transform revenue cycle operations by leading strategic initiatives, engaging stakeholders, and optimizing financial health through effective project management and collaboration across the organizati...

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  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform internal communications by designing strategies that connect corporate leadership with frontline teams. Lead a dynamic team to optimize digital channels and deliver impactful messages across...

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  •   5 - 7 years exp.  •   Food & Beverages

$80K - $95K *

Elevate your career by leading multidisciplinary teams in architectural projects, ensuring compliance and quality while coordinating efforts across phases. Drive innovation and sustainability in desig...

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  •   5 - 7 years exp.  •   Real Estate & Construction

$125K - $150K *

Join a dynamic team as you oversee billing and revenue management, ensuring accuracy and efficiency while leading a talented group. Drive process improvements and support mergers in a rapidly growing...

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  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by leading strategic digital transformation sales across industries. Drive complex pursuits integrating Cybersecurity, AI solutions, and Manufacturing Operations Management to enhance...

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  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join us to lead transformational sales in digital operations, driving complex solutions across cybersecurity and manufacturing. Collaborate with stakeholders to unlock value and accelerate customer ou...

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  •   5 - 7 years exp.  •   Manufacturing & Automotive

$211K - $285K *

Lead the charge in late-phase oncology clinical development, collaborating across teams to design and deliver impactful results. Provide expertise in clinical trial science and data analysis, ensuring...

United StatesRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$104K - $141K *

Lead the charge in transforming Human Genetics strategy into actionable plans, ensuring measurable progress across R&D. Collaborate with cross-functional teams to align priorities and drive successful...

United StatesRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $215K *

Unlock potential by managing territory accounts, driving sales of KRYSTEXXA, and building strong relationships with healthcare professionals to exceed sales goals while adhering to compliance and regu...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$144K - $194K *

Accelerate progress at the forefront of oncology marketing by leading global initiatives, synthesizing insights, and driving execution across teams to enhance product strategies and launch readiness...

United StatesRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$89K - $120K *

Drive collaboration across teams to coordinate scientific data, streamline processes, and enhance operational efficiency. This role requires strong judgment and the ability to manage cross-functional...

United StatesRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$187K - $253K *

Join a dynamic team to lead Specialty Account Managers in the IgG4-RD space, driving market penetration and achieving sales goals through strategic planning, effective resource management, and fosteri...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$143K - $194K *

Advance your career by driving GEO strategy and operations, coordinating cross-functional efforts, and optimizing digital marketing initiatives for a global brand portfolio in a dynamic and collaborat...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $215K *

Champion the promotion of innovative healthcare solutions by managing key accounts, driving sales, and educating healthcare professionals on disease management, while ensuring compliance and fostering...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$155K - $210K *

Shape the future of regulatory policy by leading initiatives that influence key decisions and drive alignment across teams. Collaborate with stakeholders to advocate for impactful policies that suppor...

United StatesRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion innovative strategies to enhance patient access and treatment in rare diseases by collaborating with key stakeholders across health systems and specialty clinics, driving operational excellen...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs can I find in Michigan?question toggle

    Listings may include leadership, technology, engineering, healthcare, finance, sales, and other specialized professional roles. Availability depends on current employer postings.

  • Which Michigan cities have professional job opportunities?question toggle

    Opportunities may be available in Detroit, Grand Rapids, Ann Arbor, Lansing, and other Michigan communities. Check each listing for its location and work arrangement.

  • Are all jobs on Ladders in Michigan guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more, but review each listing for its specific compensation details and eligibility requirements.

  • Can I find remote or hybrid jobs based in Michigan?question toggle

    Some employers may offer remote or hybrid arrangements. Work location and flexibility vary by role, so confirm the details in each job posting.