Find $100K+ Jobs in Michigan

Explore professional opportunities in Michigan with salaries of $100,000 or more. From Detroit and Grand Rapids to Ann Arbor, Lansing, and communities across the state, Ladders helps experienced professionals discover vetted roles with competitive compensation.

Explore Michigan Opportunities Across Industries

Michigan’s economy spans automotive and advanced manufacturing, healthcare, technology, finance, education, energy, and professional services. Browse senior-level and specialized openings that match your experience, skills, and career goals.

Search by Location and Career Goals

Find opportunities in major employment centers such as Detroit, Ann Arbor, Grand Rapids, and Lansing, or consider roles elsewhere in Michigan. Compare positions by responsibilities, location, work arrangement, and compensation to focus your search.

Advance Your Career with Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more. Create a profile, refine your search, and explore Michigan roles that align with your expertise and next career move. Job availability and compensation vary by employer and position.

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1,000+

Jobs in Michigan

Average Salary in USD

Average Salary: $127,832

Sort By: Relevance

$242K - $403K *

Pioneer innovative safety strategies in a dynamic environment, leading cross-functional teams to ensure optimal pharmacovigilance practices and regulatory compliance for diverse therapeutic compounds...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$83K - $95K *

Join a team that's shaping the future of nursing education by teaching innovative online Pediatrics courses. Engage students with cutting-edge methodologies and foster a vibrant online learning cultur...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$98K - $130K *

Drive financial excellence by leading cost accounting operations, ensuring accurate reporting and analysis. Collaborate across departments to support strategic business decisions and contribute to tim...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $120K *

Elevate project outcomes by leading complex architectural designs, managing teams, and ensuring quality control. Collaborate across disciplines to deliver high-impact projects while mentoring junior s...

Today

  •   15+ years exp.  •   Real Estate & Construction

$110K - $130K *

Empower project success by leading complex architectural designs, mentoring teams, and ensuring quality control. Drive collaboration across disciplines while managing schedules and budgets for large-s...

Today

  •   15+ years exp.  •   Real Estate & Construction

$195K - $264K *

Drive global regulatory strategies for obesity and cardiometabolic disorders, ensuring alignment across teams and leading interactions with health authorities. Leverage scientific expertise to navigat...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$217K - $294K *

Innovate the U.S. Cardiovascular & Metabolic Medical strategy, leading evidence generation and stakeholder engagement for chronic weight management. Collaborate cross-functionally to ensure launch rea...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Advance your career by leading operational excellence at a health center. Drive quality clinical services, enhance patient access, and ensure compliance while fostering a high-performance culture amon...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$93K - $139K *

Join a dedicated team providing technical expertise to enhance equipment reliability and performance across rotating and fixed equipment, utilizing analytics, managing changes, and ensuring adherence...

Reposted today

  •   Less than 5 years exp.  •   Energy & Utilities

$108K - $130K *

Empower clients by transforming complex challenges into AI solutions. Leverage software engineering, data science, and advanced analytics to prototype, deploy, and scale impactful AI applications that...

Today

  •   5 - 7 years exp.  •   Information Technology

$120K - $135K *

Elevate our proposal management efforts by leading strategic submissions, fostering collaboration among teams, and enhancing our pursuit capabilities to secure high-value projects that improve infrast...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Technical Services

$150K - $165K *

Transform client relationships by driving revenue growth and satisfaction in healthcare accounts. Collaborate with stakeholders to develop tailored strategies, ensuring long-term partnerships and meas...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$86K - $138K *

Lead the charge in defining and executing a comprehensive product strategy, driving value across product portfolios. Collaborate with key stakeholders to align strategic vision while overseeing perfor...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$134K - $223K *

Lead digital web projects, ensuring optimal performance and compliance across the GSK.com platform. Collaborate with cross-functional teams to enhance user experience, mitigate cybersecurity risks, an...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Champion the go-to-market strategy and execution for a regional portfolio, driving growth and lifecycle management. Collaborate with stakeholders to adapt global strategies to local markets, ensuring...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Lead the charge in delivering complex renewable energy projects, ensuring safety, quality, and budget adherence. Collaborate with diverse stakeholders to drive project success from development through...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$90K - $100K *

Join a team that's driving franchise sales success by leading, coaching, and developing a high-performing sales team. Optimize processes, leverage analytics, and collaborate across departments to enha...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

$80K - $95K *

Elevate your career as a Senior Accountant, driving day-to-day operations and enhancing internal processes. Collaborate with teams to transition activities, ensuring accuracy and scalability in a fast...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Execute multi-channel marketing campaigns, driving results through strategic planning and collaboration. Own project timelines and coordinate teams to enhance player engagement in the crypto and iGami...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Drive resolution of product development and quality issues, develop KPIs, and collaborate with engineering teams to ensure project milestones are met. Monitor warranty performance and create visual da...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Help us develop innovative automotive components from concept to production, managing timelines and ensuring quality through design validation and testing. Collaborate with cross-functional teams to d...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Engineer innovative EMC solutions by co-owning the virtual EMI/EMC roadmap, leading simulation workflows, and providing expert guidance to ensure product integrity and compliance across diverse applic...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $165K *

Drive customer success in Cancer Registry by building relationships, enhancing retention, and translating insights into actionable solutions. Collaborate across teams to improve outcomes and shape bus...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Deliver innovative solutions in biologics analytical sciences, focusing on the characterization of biological molecules and method development. Collaborate with interdisciplinary teams to enhance biop...

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$93K - $153K *

Join a dynamic team to organize and deliver clinical study reports, coordinate meetings, and ensure compliance with regulatory standards while fostering strong relationships with sites and stakeholder...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs can I find in Michigan?question toggle

    Listings may include leadership, technology, engineering, healthcare, finance, sales, and other specialized professional roles. Availability depends on current employer postings.

  • Which Michigan cities have professional job opportunities?question toggle

    Opportunities may be available in Detroit, Grand Rapids, Ann Arbor, Lansing, and other Michigan communities. Check each listing for its location and work arrangement.

  • Are all jobs on Ladders in Michigan guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more, but review each listing for its specific compensation details and eligibility requirements.

  • Can I find remote or hybrid jobs based in Michigan?question toggle

    Some employers may offer remote or hybrid arrangements. Work location and flexibility vary by role, so confirm the details in each job posting.