Explore $100K+ Jobs in Colorado

Discover vetted professional opportunities across Colorado with salaries of $100,000 or more. From established employers in Denver to growing companies in Boulder, Colorado Springs, and beyond, Ladders helps experienced professionals find roles that match their skills and career goals.

Find Opportunities Across Colorado

Colorado’s job market spans major metropolitan areas and communities throughout the state. Search for senior-level and executive openings in Denver, Boulder, Colorado Springs, Fort Collins, and other locations. Available opportunities vary by employer and industry, so explore current listings to see where your experience is in demand.

Explore Professional Roles and Industries

Colorado employers hire experienced professionals across fields such as technology, finance, healthcare, engineering, energy, operations, and sales. Browse listings by role, location, and other preferences to focus your search on positions suited to your background.

Make Your Colorado Job Search Count

Use Ladders to explore vetted jobs paying $100,000 or more. Refine your search by location and career interests, review role requirements, and apply to positions that align with your qualifications. Check back regularly for new opportunities across Colorado.

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$127K - $223K *

Transform the way we communicate life insurance through compelling copy that captures attention and drives action. Collaborate with teams to create impactful Direct Mail and social media content that...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Drive innovative solutions by leveraging your expertise in project management, collaborating with cross-functional teams to enhance operational efficiency and deliver impactful results across diverse...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$225K - $281K *

Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape client success by leading complex consulting projects, integrating diverse workstreams into actionable insights, and driving high-quality deliverables while fostering team growth and managing st...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $156K *

Shape the future of clinical trials by managing the execution and oversight of Class III medical device studies. Collaborate with teams and ensure compliance, quality standards, and operational succes...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$154K - $177K *

Advance your career by leading statistical programming efforts in clinical trials. Collaborate with cross-functional teams to ensure data quality and compliance while driving process improvements and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $145K *

Elevate medical communications by developing high-quality, strategic content across therapeutic areas. Collaborate with teams and clients to ensure accuracy and adherence to guidelines while supervisi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $100K *

Unlock potential by covering advanced therapies and drug technologies. This role demands a business-savvy, science-minded journalist to report on clinical trials and industry trends, shaping the narra...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Media

$85K - $105K *

Join a team that's dedicated to delivering impactful medical communications. As a Senior Account Manager, you'll lead strategic projects for pharmaceutical clients, ensuring quality and timely executi...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$81K - $118K *

Innovate analytical strategies to enhance toxicology assessments, ensuring compliance and data integrity. Collaborate across teams to drive project success and influence decision-making through advanc...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Champion the development and oversight of scientific content across multiple therapeutic areas, ensuring strategic brand planning and growth through effective client interactions and project managemen...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $154K *

Drive the development of project specifications and procurement documentation, ensuring design excellence and risk management across complex projects while collaborating with multidisciplinary teams a...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$80K - $95K *

Pioneer impactful patient engagement by transforming behavioral science into compelling content. Collaborate with cross-functional teams to drive healthcare improvements while utilizing innovative AI...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Drive regulatory intelligence initiatives to ensure compliance and support clinical research. Collaborate with experts to assess regulatory changes, track global guidelines, and enhance impact assessm...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$189K - $246K *

Lead clinical pharmacology strategies, integrating PK/PD assessments across development phases. Collaborate with cross-functional teams to guide decision-making and regulatory submissions, ensuring al...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive regulatory strategy across major programs, leading high-impact submissions and authority engagement. Collaborate with cross-functional teams to optimize clinical development and ensure complianc...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive impactful medical communications projects from start to finish, ensuring timely execution and client satisfaction. Collaborate with multidisciplinary teams, manage budgets, and foster strong rel...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $95K *

Advance your career by managing diverse medical communications projects, ensuring timely delivery and client satisfaction while leading multidisciplinary teams and maintaining strong relationships wit...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$177K - $283K *

Lead statistical strategy for clinical trials, innovating study designs and analyses at a program level. Influence decision-making with data-driven insights while collaborating across teams to enhance...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$246K - $332K *

Shape the future of health economics and outcomes research by leading strategic initiatives across the nephrology portfolio, ensuring high-quality evidence generation and collaboration with cross-func...

RemoteRemote

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$203K - $305K *

Transform regulatory intelligence by leading a global strategy that identifies and implements evolving regulatory requirements across diverse healthcare sectors, ensuring compliance and strategic alig...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$76K - $148K *

Play a key role in managing clinical trials, ensuring compliance and quality oversight of project deliverables while collaborating with cross-functional teams to meet timelines and budget goals...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Lead the charge in shaping innovative media strategies while collaborating with agency teams and central resources. Drive holistic media planning, enhance client engagement, and optimize offerings to...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$117K - $176K *

Empower your career by leading cross-functional teams to craft compelling narratives that drive strategic pursuits. Utilize your expertise in clinical development and storytelling to enhance customer...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100K+ jobs can I find in Colorado?question toggle

    Listings may include senior and executive roles across fields such as technology, finance, healthcare, engineering, energy, operations, and sales. Available jobs and requirements vary by employer.

  • Where in Colorado can I search for professional jobs?question toggle

    Explore opportunities in Denver, Boulder, Colorado Springs, Fort Collins, and other Colorado communities. Use location filters to find jobs in your preferred area.

  • How can I find jobs in Colorado that pay $100,000 or more?question toggle

    Browse Colorado listings on Ladders and filter by location, role, and other preferences. Review each posting for compensation details and qualifications.

  • Are Colorado jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs paying $100,000 or more. Check individual listings for details about the employer, responsibilities, and requirements.