Explore $100K+ Jobs in Colorado

Discover vetted professional opportunities across Colorado with salaries of $100,000 or more. From established employers in Denver to growing companies in Boulder, Colorado Springs, and beyond, Ladders helps experienced professionals find roles that match their skills and career goals.

Find Opportunities Across Colorado

Colorado’s job market spans major metropolitan areas and communities throughout the state. Search for senior-level and executive openings in Denver, Boulder, Colorado Springs, Fort Collins, and other locations. Available opportunities vary by employer and industry, so explore current listings to see where your experience is in demand.

Explore Professional Roles and Industries

Colorado employers hire experienced professionals across fields such as technology, finance, healthcare, engineering, energy, operations, and sales. Browse listings by role, location, and other preferences to focus your search on positions suited to your background.

Make Your Colorado Job Search Count

Use Ladders to explore vetted jobs paying $100,000 or more. Refine your search by location and career interests, review role requirements, and apply to positions that align with your qualifications. Check back regularly for new opportunities across Colorado.

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$150K - $180K *

Drive impactful scientific communication by overseeing content development across therapeutic areas, ensuring strategic alignment with client goals while managing a team and collaborating with various...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $150K *

Join a team that's transforming complex regulations into clear, actionable insights. You'll lead the creation of educational content that empowers clients in the financial services sector to navigate...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$104K - $166K *

Lead the charge in developing and maintaining technical documentation standards, ensuring clarity and accuracy across digital-twin capabilities. Collaborate with cross-functional teams to produce high...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$81K *

Transform medical monitoring processes by reviewing data, developing plans, and collaborating with teams to ensure compliance and resolve clinical issues. Support Medical Directors in enhancing projec...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to transforming data into actionable insights. As a Senior Analyst, you'll tackle complex challenges, support strategic initiatives, and collaborate with experts to enhanc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $310K *

Transform clinical AI through rigorous scientific publications and evidence generation. Collaborate with diverse teams to lead complex projects, ensuring clarity and credibility in communications whil...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$90K - $130K *

Elevate your career by managing and enhancing technical documentation across platforms. Collaborate with teams to ensure accuracy and consistency while utilizing your expertise in Microsoft Word and S...

Westminster, CORemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $130K *

Support the creation and maintenance of technical documentation across platforms. Collaborate with teams to ensure accuracy and consistency while managing revisions and updates in a fast-paced environ...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$81K - $151K *

Advance your career by creating and managing technical documentation for cutting-edge avionics systems. Collaborate with experts to ensure clarity and compliance in a dynamic environment, contributing...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$90K *

Contribute to high-impact proposal development by crafting persuasive narratives that align with client needs and competitive positioning, ensuring compliance and strategic messaging throughout the pr...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Shape the future of technical proposals by collaborating with cross-functional teams to create compelling, scientifically accurate documents that meet client needs and drive business success in the li...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Champion global labeling strategy for innovative therapies, leading complex initiatives from development to post-approval. Collaborate with cross-functional teams to ensure compliance and high-quality...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$70K - $105K *

Collaborate with cross-functional teams to drive project execution and operational excellence in medical communications. Leverage your project management skills to ensure timely delivery and high-qual...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$191K - $238K *

Shape the future of oncology by leading medical strategy for prostate cancer projects. Collaborate with cross-functional teams to drive scientific communication and strategic initiatives, ensuring ali...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$89K - $105K *

Deliver compelling marketing and policy content that enhances brand voice and reputation. Collaborate with teams to translate complex topics into clear narratives, ensuring high-quality, timely materi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$183K - $294K *

Transform healthcare outcomes by leveraging data-driven insights and strategic problem-solving. Lead payer engagement initiatives, manage substantial budgets, and influence key stakeholders to enhance...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Join a team that's redefining marketing excellence by executing strategic campaigns across subscriptions, events, and sales enablement. You'll collaborate with diverse teams, manage dynamic projects...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Lead the charge in clinical pharmacology, ensuring compliance and excellence in drug development. Collaborate with cross-functional teams to design and implement studies, contributing to global clinic...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$102K - $108K *

Advance ocean science by connecting stakeholders and managing partnerships. Lead the Coastal Acidification Network, coordinate international collaborations, and mentor future ocean science professiona...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $195K *

Empower quality assurance excellence by leading GMP oversight for contract manufacturing and validation projects, ensuring compliance and collaboration across technical operations to support drug deve...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Lead the charge in developing high-quality medical content across multiple projects, ensuring strategic alignment and regulatory compliance while collaborating with cross-functional teams and supervis...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Join as a critical team member to manage and enhance productivity platforms, ensuring stability, security, and user satisfaction. Collaborate across teams to drive operational maturity and navigate co...

RemoteRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Business Services

$175K - $215K *

Elevate the technology function by leading engineering, delivery, and operations. Collaborate closely with leadership to shape technical strategy, ship code weekly, and ensure high standards in a dyna...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Media

$85K - $95K *

Lead a dynamic team to enhance documentation processes, ensuring clarity and compliance across multidisciplinary projects while collaborating with engineers and stakeholders to drive innovative commun...

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$65K - $105K *

Lead the charge in developing and managing technical documentation for a NATO SATCOM modernization program, ensuring accuracy and compliance throughout the system lifecycle while collaborating with mu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What kinds of $100K+ jobs can I find in Colorado?question toggle

    Listings may include senior and executive roles across fields such as technology, finance, healthcare, engineering, energy, operations, and sales. Available jobs and requirements vary by employer.

  • Where in Colorado can I search for professional jobs?question toggle

    Explore opportunities in Denver, Boulder, Colorado Springs, Fort Collins, and other Colorado communities. Use location filters to find jobs in your preferred area.

  • How can I find jobs in Colorado that pay $100,000 or more?question toggle

    Browse Colorado listings on Ladders and filter by location, role, and other preferences. Review each posting for compensation details and qualifications.

  • Are Colorado jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs paying $100,000 or more. Check individual listings for details about the employer, responsibilities, and requirements.