Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,896

Sort By: Relevance

$121K - $233K *

Champion the execution of large-scale projects in Fiber Engineering, leading diverse teams to innovate and drive operational excellence while managing resources and stakeholder relationships for impac...

1 week ago

  •   8 - 10 years exp.  •   Transportation

$104K - $171K *

Lead the charge in financial planning and analysis, driving strategic insights and operational improvements. Collaborate with cross-functional teams to enhance financial systems and ensure data integr...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $155K *

Drive the strategy and roadmap for Bot Management solutions, ensuring alignment with customer needs and market trends. Collaborate with cross-functional teams to innovate and deliver effective cyberse...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$190K *

Optimize engineering services by leading DevOps and SRE teams, enhancing CI/CD processes, and ensuring data governance. Drive operational excellence and security while fostering a collaborative enviro...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$275K - $330K *

Transform cloud services architecture and lead innovative design initiatives. As a Principal Engineer, you'll drive technical direction, optimize data models, and mentor teams to enhance software deli...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$145K - $290K *

Drive contract management strategies by enhancing processes, optimizing sales operations, and providing leadership for vendor negotiations and team performance alignment. Engage with cross-functional...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $174K *

Grow your career with a dynamic role driving upstream marketing for Advanced Imaging solutions, managing product lifecycles, and collaborating with cross-functional teams to enhance customer value and...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$98K - $155K *

Empower logistics excellence by leading warehouse operations and 3PL coordination. Drive inventory accuracy, compliance, and continuous improvement while managing teams and optimizing processes for ef...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$136K - $216K *

Lead the charge in advancing innovative healthcare solutions by managing the Exploratory Innovation Teams program. Collaborate with cross-functional partners to enhance portfolio processes and drive s...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $133K *

Innovate with us to deliver AI and machine learning solutions that transform data into actionable insights. Collaborate across teams to enhance fraud detection and anomaly analysis, leveraging advance...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$113K - $188K *

Transform data into insights by developing cutting-edge machine learning models. Collaborate with multidisciplinary teams to address complex business needs using advanced analytics, ensuring data-driv...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$130K - $216K *

Transform enterprise Databricks environments with innovative designs, ensuring secure, efficient implementations while collaborating with stakeholders to deliver scalable data solutions and enhance go...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$74K - $124K *

Lead impactful projects in affordable housing finance and policy implementation. Collaborate with public-sector clients to enhance program design and operational efficiency, ensuring effective use of...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$89K - $148K *

Champion change management during EHR implementation, guiding users through training and support, while fostering stakeholder relationships to align with program objectives and enhance workflow for a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$78K - $108K *

Join a dynamic team to enhance student experiences through innovative industry partnerships and experiential learning programs, driving strategic initiatives that prepare the next generation of creati...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$45K - $250K *

Transform your career by connecting healthcare professionals with meaningful roles. Join a supportive team focused on building relationships and driving results while enjoying unlimited earning potent...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $95K *

Provide skilled nursing care to participants in their homes, ensuring comprehensive, coordinated, and compassionate support. Collaborate with an interdisciplinary team to enhance participants’ indepen...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $376K *

Lead the charge in clinical development strategy, guiding cross-functional teams to ensure timely execution of pre-clinical assets while maintaining high scientific standards and stakeholder alignment...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by leading the deployment and support of cutting-edge robotic solutions. Manage logistics, field operations, and service excellence while ensuring safety and compliance across diverse...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$153K - $166K *

Join a team that's shaping the future of AI governance in software development. As a Senior Engineer, you'll design policies and tools that ensure safe, effective use of AI coding agents, empowering d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$104K - $155K *

Lead and innovate in AP Test Publishing, overseeing print exam production and vendor collaboration to ensure equitable access and high-quality materials for students worldwide. Drive strategic plannin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$104K - $160K *

Champion integrity in assessment operations by leading a team to resolve testing irregularities and enhance automated processes, ensuring equitable testing experiences for all students while driving s...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$76K - $120K *

Take ownership of critical operational pipelines as a Research Statistician, executing analyses and improving processes to ensure the SAT Suite runs smoothly. Collaborate with cross-functional teams t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $160K *

Empower the Claims organization by leading training and development initiatives. Drive strategic coverage analysis and enhance claims management skills through innovative learning programs for profess...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$153K - $229K *

Join a team that's driving digital transformation in Medical Affairs. In this strategic role, you'll lead IT initiatives, champion innovation, and enhance operational excellence to support scientific...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.