Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,896

Sort By: Relevance

$94K - $170K *

Drive digital transformation in manufacturing by leveraging Mendix and AI solutions. Collaborate with cross-functional teams to enhance operational performance, compliance, and user experience through...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$199K - $366K *

Discover a pivotal leadership role in internal audit, driving governance and risk management across a dynamic organization. Influence strategic objectives and enhance internal controls while mentoring...

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$196K - $342K *

Drive the Quality organization for the VET Platform, overseeing strategic initiatives and managing teams. Collaborate cross-functionally to enhance product quality and processes, ensuring compliance a...

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$78K - $125K *

Shape the future of executive support by providing high-level administrative assistance to senior leaders. Drive organizational efficiency and enable strategic decision-making in a dynamic, fast-paced...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$109K - $174K *

Lead the development of innovative surgical navigation systems in orthopaedics. Collaborate with cross-functional teams to define requirements, conduct risk analysis, and ensure system reliability for...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$137K - $235K *

Lead a dynamic team to advance data science and AI capabilities in Finance. Drive impactful analytics solutions that enhance decision-making and efficiency across key financial processes, while foster...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$109K - $174K *

Transform the future of healthcare by coordinating regulatory submissions and strategies for innovative medical devices, ensuring compliance and supporting product lifecycle management in a dynamic en...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$122K - $212K *

Lead the charge in shaping financial reporting and analytics strategies. Drive governance and delivery of insights while enhancing automation and scalability. Collaborate across teams to ensure accura...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Engage with dually-eligible enrollees to provide integrated care management, ensuring seamless communication among healthcare providers and community resources to enhance health outcomes and quality o...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Join us to enhance care for dually-eligible enrollees by integrating health services and community resources. This role focuses on clinical management, ensuring seamless communication and improved hea...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Oversee integrated care management for dually-eligible enrollees, coordinating health services and community resources to enhance health outcomes and quality of life through effective communication an...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Lead the charge in integrated care management for dually-eligible enrollees, focusing on holistic health solutions and community resource coordination to enhance quality of life and health outcomes fo...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Join a dedicated team to optimize care for dually-eligible enrollees, focusing on complex medical, behavioral, and social needs. Engage with members in their communities to enhance health outcomes and...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Champion integrated care management for dually-eligible enrollees, focusing on complex medical, behavioral, and social needs. Collaborate with healthcare providers and community resources to enhance h...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Join a dynamic team to enhance care for dually-eligible enrollees by integrating health services and community resources, ensuring comprehensive support for complex medical, behavioral, and social nee...

Today

  •   Less than 5 years exp.  •   Healthcare

$94K - $164K *

Champion user experience design across digital products, driving insights into actionable solutions. Collaborate with cross-functional teams to enhance customer journeys and ensure alignment with Huma...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$94K - $164K *

Champion cost reporting processes by ensuring data accuracy, preparing detailed reports, and analyzing financial information. Collaborate across departments to enhance reporting systems and support st...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$113K - $197K *

Lead regulatory and compliance oversight for Operations, ensuring accuracy and efficiency. Collaborate with enterprise partners to enhance operational processes, implement automation, and drive contin...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$94K - $164K *

Champion technical delivery and governance for enterprise release management, ensuring reliable software deployment and continuous improvement across teams while driving AI adoption and enhancing oper...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$72K - $115K *

Partner with us to design and validate predictive models that enhance business processes across various domains, leveraging data science techniques to drive insights and improve decision-making within...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$81K - $121K *

Transform retail partnerships by coaching top sellers, driving sales growth, and executing strategic plans to enhance agricultural product adoption and profitability in a dynamic, remote environment...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Food & Beverages

$136K - $253K *

Elevate your career by leading sales strategies and fostering dealer relationships to achieve market share goals. Drive team success through effective communication and innovative sales tools while ma...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$86K - $137K *

Optimize project outcomes as you manage small to medium-sized initiatives. Collaborate across teams, navigate risks, and ensure timely delivery of quality solutions while enhancing communication and s...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $180K *

Unlock potential by joining a dynamic team as a Senior Business Analyst, where you'll bridge regulatory, compliance, and technology efforts to drive strategic solutions and enhance operational control...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$129K - $177K *

Lead the charge in orchestrating complex workflows and action delivery on a cutting-edge platform. Collaborate with a small team to ensure seamless member engagement through technology solutions that...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.