Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.
Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.
Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.
Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.
Average Salary: $126,012
Guidance Senior Advanced Systems Engineer
$142K - $158K *
Lead the charge in developing innovative guidance systems, leveraging your expertise in engineering and analysis. Collaborate with cross-functional teams to enhance technologies and support critical d...
3 days ago
Senior Guidance Systems Engineer
$100K - $111K *
Innovate your career by joining a dynamic team focused on guidance systems analysis, design, and implementation. Collaborate on cutting-edge projects while advancing technologies in inertial guidance...
3 days ago
Cleared Full Stack Engineer - (Java/React) Multiple Levels
$99K - $182K *
Drive innovation as a Full Stack Engineer, developing mission-critical Cybersecurity applications. Collaborate with cross-functional teams to enhance advanced Encryptor Manager technology using cuttin...
3 days ago
Systems Security Engineer Multiple Levels (cleared)
$99K - $182K *
Shape the future of cybersecurity by designing NSA-certified devices. Collaborate with engineering teams to develop innovative solutions, ensuring system security throughout the product lifecycle whil...
3 days ago
$95K - $105K *
Pioneer innovative solutions as a systems engineer, collaborating with cross-functional teams to modernize strategic submarine fleet initiatives, ensuring national security through advanced design and...
3 days ago
Systems Engineering Lead (cleared)
$164K - $182K *
Lead systems development efforts for Crypto & Cross Domain Solutions, guiding a cross-functional team in the Space, Cyber, and Intelligence sector. Drive innovation and ensure successful project execu...
3 days ago
$166K - $200K *
Shape the future of healthcare technology by leading engineering for patient-centric systems. Drive innovation, ensure compliance, and mentor teams to deliver safe, efficient clinical solutions that e...
3 days ago
$86K - $165K *
Elevate software solutions by leading full lifecycle development in a collaborative environment. Utilize agile methodologies and advanced engineering practices to deliver innovative products that meet...
3 days ago
$90K - $110K *
Elevate your career by managing a diverse portfolio of retail and industrial properties across multiple states. This hands-on role focuses on operational excellence, financial performance, and tenant...
3 days ago
Senior Director/Vice President Translational Medicine
$230K - $330K *
Unlock the potential of translational medicine by leading biomarker strategies and clinical development across immunology programs. Collaborate with cross-functional teams to drive innovative solution...
3 days ago
$125K - $150K *
Accelerate revenue growth by building relationships with sales reps, dealers, and designers. Train and inspire teams across North America, while managing key projects and collaborating with internal t...
Reposted 3 days ago
Research Software Developer II
$95K - $115K *
Transform software development for medical imaging by leveraging expertise in Python, 3D geometry, and graphics APIs. Collaborate with engineering and clinical teams to enhance applications for surgic...
3 days ago
$115K - $140K *
Transform the future of transportation by leading complex highway projects, mentoring engineers, and delivering innovative solutions that enhance infrastructure safety and performance...
3 days ago
Clinical Study Start-Up Associate
$90K - $110K *
Champion study start-up activities by coordinating documentation, managing timelines, and collaborating with cross-functional teams to ensure timely activation of clinical trials in a fast-paced envir...
3 days ago
$112K - $197K *
Champion patient care and community health by leading pharmacy operations, ensuring compliance, and enhancing team performance. Drive outreach initiatives while managing staff and delivering exception...
3 days ago
Automotive Sales Manager - Audi Brookline
$125K - $175K *
Elevate your career by driving sales success and developing talent in the automotive industry. Lead a dynamic team, enhance customer experiences, and redefine the car-buying journey while achieving mo...
3 days ago
Shreveport, LA based Clinical Specialist - Remote, USA
$100K - $140K *
Grow your career with a dynamic role in clinical support, training surgical teams, and ensuring optimal patient outcomes in complex procedures. Collaborate closely with medical professionals, manage i...
Reposted 3 days ago
$245K - $255K *
Lead the charge in biostatistics for clinical studies, ensuring high-quality deliverables through collaboration with cross-functional teams and external partners, while driving innovative methodologie...
3 days ago
Senior AI Software Engineer (Healthcare)
$120K - $145K *
Engage in cutting-edge AI development by designing and scaling intelligent applications. Leverage Generative AI and modern tools to enhance productivity and integrate workflows within healthcare platf...
Reposted 3 days ago
Digital Product Design Manager
$94K - $270K *
Transform the way products are designed by leading teams to create innovative user experiences. Own the full cycle from ideation to delivery while cultivating talent and driving business growth throug...
Reposted 3 days ago
Senior Product Manager, Clinical Development Platforms
$155K - $200K *
Elevate product management by driving vision, strategy, and execution across digital solutions in clinical development. Collaborate with cross-functional teams to enhance user experience and operation...
3 days ago
$80K - $95K *
Shape the future of client relationships in the metals industry by driving sales, managing key accounts, and ensuring customer satisfaction. Leverage market expertise to identify opportunities and fos...
Reposted 3 days ago
Business Development Representative
$91K *
Empower your career as a Business Development Representative, driving outbound leads and customer opportunities. Collaborate with teams to enhance strategies and mentor peers while shaping the future...
3 days ago
Sr. Manager, IT SOX Compliance
$103K - $184K *
Transform compliance processes by leading IT SOX initiatives, ensuring robust internal controls and regulatory adherence across the organization while collaborating with cross-functional teams to miti...
3 days ago
Account Executive/Senior Account Executive
$90K - $150K *
Lead your career with a pivotal role in strategic sales, driving revenue through exceptional account management and cultivating strong relationships with agencies and clients to expand our innovative...
Reposted 3 days ago
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.
Where in Massachusetts can I find high-paying jobs?
Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.
How can I search for Massachusetts jobs paying $100,000 or more?
Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.
Are Massachusetts jobs on Ladders vetted?
Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.