Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,012

Sort By: Relevance

$112K - $130K *

Unlock potential by providing newly graduated nurse practitioners with hands-on training in primary care. Collaborate with healthcare teams to manage patient panels while developing critical skills in...

3 days ago

  •   Less than 5 years exp.  •   Staffing

$92K - $138K *

Transform operational effectiveness by leading implementation initiatives across regions. Collaborate with teams to ensure successful activation, training, and adoption of non-medical changes, enhanci...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Technical Services

$130K - $242K *

Lead advanced analytics initiatives to enhance MAU insights, driving growth through experimentation and causal inference. Collaborate across teams to establish standards and leverage AI for scalable s...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$83K - $88K *

Shape the future of healthcare by leading nursing teams, enhancing client care, and driving policy development. Collaborate with program staff to ensure effective health evaluations and training, whil...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$214K - $268K *

Shape the strategy and outcomes for compliance and platform products, leading a team of product managers and domain experts. Drive innovation and customer engagement while ensuring enterprise-scale de...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$110K - $120K *

Empower your career by leading business analysis and configuration efforts. Collaborate with stakeholders to translate objectives into actionable requirements, ensuring successful project delivery and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $145K *

Lead the Sales Enablement team to drive impactful initiatives, collaborating with cross-functional leaders to enhance sales effectiveness in a fast-paced AI environment. Balance priorities and deliver...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$152K - $203K *

Drive the development and deployment of scalable ML models, optimizing workflows and infrastructure. Collaborate with cross-functional teams to ensure reliability and security in ML operations, enhanc...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Champion the advancement of graduate neuroscience education through strategic leadership in curriculum design, program evaluation, and professional development initiatives, fostering a culture of cont...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K *

Lead the care team in assessing resident health and developing personalized care plans. Ensure compliance with regulations while fostering positive relationships with residents, families, and staff in...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$104K *

Transform lives by providing essential medical care and support in a structured environment for adults facing substance use challenges. Collaborate with a dedicated team to ensure effective treatment...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$69K - $95K *

Engage with stakeholders to prioritize and refine product backlogs, ensuring clarity and efficiency in development. Collaborate with cross-functional teams to drive innovative solutions and enhance us...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$290K - $342K *

Drive global partner and channel strategy, enhancing relationships and expanding market reach. Lead a high-performing team to innovate and execute programs that boost cross-sell opportunities and esta...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Information Technology

$100K *

Advance resident care by assessing health needs, designing care plans, and ensuring compliance with regulations. Collaborate with staff and families to enhance quality of life for residents in a suppo...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$170K - $234K *

Join a team that's redefining AI systems by leading the design and delivery of innovative ML solutions. Drive architectural decisions, mentor engineers, and shape AI strategy while ensuring reliabilit...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$76K - $114K *

Join a team that's dedicated to enhancing workplace safety and environmental compliance. This role supports EHS programs, collaborates with site leaders, and ensures regulatory adherence across variou...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $140K *

Join a team that's focused on optimizing technical operations within a regulated pharmaceutical environment, ensuring compliance, efficiency, and reliability through advanced planning, collaboration...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $176K *

Shape the future of AI-driven products by leading the development and market launch of innovative solutions. Collaborate with teams to enhance customer experiences and drive product success through st...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$85K - $90K *

Champion the safe and efficient transportation of food products, overseeing daily operations, supervising staff, and ensuring compliance with DOT regulations while enhancing customer satisfaction and...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$150K - $180K *

Drive sales excellence by leading a high-performing team, executing strategic plans, and enhancing customer experiences in a dynamic, early-stage commercialization environment. Foster collaboration an...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $120K *

Champion strategic initiatives by partnering with leadership to drive growth, optimize operations, and support new business innovations. Leverage analytical skills to develop insights and execute key...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join our team to craft compelling narratives that engage government evaluators. Collaborate with proposal writers and subject matter experts to transform technical content into persuasive stories whil...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $170K *

Lead production management to enhance storytelling across campaigns and creative projects. Collaborate with diverse teams, optimizing workflows and ensuring high standards in execution, while driving...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$95K - $250K *

Drive energy efficiency by conducting home assessments, diagnosing issues, and recommending solutions. Collaborate with homeowners to enhance energy savings while providing exceptional customer servic...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$95K - $250K *

Champion energy efficiency by conducting home assessments, diagnosing issues, and recommending solutions. Leverage your sales skills to educate homeowners and secure contracts while collaborating with...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.