Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$105K - $120K *

Empower healthcare professionals by engaging remotely with cardiologists, nephrologists, and primary care providers. Drive sales and support efforts in open territories while delivering a consistent e...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$50K - $175K *

Inspire automotive sales excellence by cultivating strong client relationships, showcasing vehicles, and driving customer satisfaction, while continuously enhancing product knowledge and sales techniq...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Join a dynamic team to manage tax compliance and planning across multiple entities. Collaborate with Finance, Legal, and Operations to enhance tax processes and support strategic projects in a growing...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Elevate clinical research by ensuring investigational sites meet study standards. Conduct monitoring visits, train staff, and support regulatory submissions while mentoring junior team members in a dy...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$113K - $140K *

Champion the reliability and performance of critical systems, driving architecture evolution and incident response. Collaborate with a skilled team across AWS and Azure, ensuring security and scalabil...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$72K - $111K *

Champion the implementation of restorative practices in schools, fostering relationships and collaboration among staff, students, and families. Drive program development, assess effectiveness, and sup...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$17K - $295K *

Lead the charge in providing senior technical strategy within Risk and Security, collaborating with partners to co-create solutions, drive adoption of AI capabilities, and enhance partner maturity thr...

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $175K *

Optimize strategies by leading multi-channel collections initiatives, leveraging analytics and AI to enhance performance and drive payment conversions. Collaborate cross-functionally to design and imp...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $150K *

Join a dynamic team to oversee construction projects from inception to completion. Drive project success by coordinating with stakeholders, ensuring compliance, and managing budgets and schedules for...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$160K - $180K *

Transform the future of cloud infrastructure by leading DevOps initiatives, enhancing systems integration, and driving innovative solutions for federal clients. Collaborate with stakeholders to optimi...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $140K *

Join us in transforming digital services for Veterans. As a Senior Designer, you'll lead user experience initiatives, conduct research, and shape information architecture for a large digital portal, e...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Transform the future of digital engagement by leading Adobe Target implementations. Collaborate across teams to develop personalized strategies that enhance user experiences and drive measurable busin...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Transform data integration in modern data centers by leading a team to design and implement edge collectors, ensuring seamless connectivity and efficient onboarding across multiple sites while collabo...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$195K - $230K *

Join a team that's redefining partnership development in the fintech space. You'll drive new opportunities with PSPs and banks, managing complex deals and collaborating cross-functionally to enhance C...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Join a team that's dedicated to enhancing public health by leading procurement and financial operations. You'll manage a skilled team, ensuring compliance and efficiency while addressing health dispar...

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$120K - $145K *

Champion a team of legal professionals in enforcing healthcare regulations, ensuring accountability and public safety. Lead complex litigation, mentor attorneys, and enhance case management practices...

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$81K - $85K *

Join a team that's dedicated to enhancing the lives of adults in foster care. As a Registered Nurse, you'll oversee health monitoring, coordinate care plans, and support caregivers, ensuring quality s...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $225K *

Join a team that's dedicated to enhancing manufacturing processes and driving innovation. Collaborate cross-functionally to design assembly layouts, develop tooling, and improve production efficiency...

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$83K - $90K *

Join a team that's dedicated to empowering children through speech therapy. Provide assessments and therapy in diverse settings while collaborating with a multidisciplinary team to support families an...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$76K - $90K *

Shape the future of compassionate care by providing essential nursing services in a supportive residential environment, ensuring the well-being of medically involved individuals through structured rou...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$114K - $156K *

Elevate patient care as a Nurse Practitioner, conducting evaluations, developing treatment plans, and prescribing medications in a collaborative outpatient setting focused on opioid recovery. Join us...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform market access strategies by leading diverse projects, mentoring teams, and driving client engagement while navigating complex healthcare landscapes and delivering value-driven insight across...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$216K - $361K *

Elevate your career by driving sales growth in enterprise software across retail, energy management, and telecommunications. Collaborate with top clients to achieve strategic goals and expand market p...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$68K - $102K *

Help us shape the future of project delivery by managing customer projects from concept to completion, ensuring quality and satisfaction while coordinating diverse teams and resources effectively...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $112K *

Shape the future of patient care by providing expert nursing support in a dynamic treatment environment. Collaborate with a multidisciplinary team to deliver high-quality care for individuals facing s...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.