Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$100K - $120K *

Empower our provider team's mission by designing innovative tools for therapists. You'll create streamlined solutions that enhance patient care, drive efficiency, and leverage technology while collabo...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Drive your career with a leadership role focused on Revenue Integrity, overseeing strategic direction, performance metrics, and team development to enhance operational efficiency and client satisfacti...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$153K - $235K *

Shape the future of sales effectiveness by leading complex client engagements, building trusted relationships, and developing high-performing teams to enhance sales performance through innovative comp...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K *

Join our dynamic sales team to drive net-new logo sales in the mid-market and enterprise sectors. Leverage your HRMS/Payroll expertise to exceed quotas and deliver exceptional solutions, supported by...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$149K - $198K *

Elevate user experience by architecting and implementing visualization solutions. Collaborate across teams to enhance automated testing and drive best practices in performance and scalability, deliver...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Transportation

$149K - $198K *

Innovate visualization solutions that enhance user experiences across diverse teams. Collaborate on complex workflows, drive best practices in performance, and deliver value quickly in a dynamic, prod...

3 days ago

  •   Less than 5 years exp.  •   Transportation

$142K - $170K *

Transform the organic social landscape through strategic execution, driving audience engagement and brand growth via compelling content on LinkedIn, Instagram, and YouTube, while collaborating cross-f...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $200K *

Drive account growth by managing client relationships and fostering strategic partnerships. This dynamic role engages with clients, executing sales strategies to expand product adoption while ensuring...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$124K - $187K *

Drive the future of QA by leading AI-enhanced test automation strategies. Oversee the transition from Selenium to Playwright, guiding offshore teams and ensuring quality benchmarks across diverse plat...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Take ownership of medication therapy management services, conducting comprehensive reviews and consultations. Collaborate with the MTM product team to ensure accurate data entry and enhance patient ca...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$106K - $132K *

Elevate business development efforts by conducting strategic analysis, sourcing novel drug ideas, and constructing compelling investment cases to drive growth and support transformative therapies in t...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $153K *

Champion the future of trading support by providing critical technology assistance to traders. Ensure system stability and performance in a fast-paced environment while managing incidents and collabor...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $160K *

Lead the charge in advancing innovative mRNA constructs for autoimmune therapies. Collaborate with cross-functional teams to optimize drug candidates from discovery through preclinical development, dr...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$82K - $153K *

Transform patient care by planning, delivering, and managing nursing services. Collaborate with healthcare teams to ensure quality and continuity of care while adhering to nursing standards and promot...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $500K *

Transform legal operations by building efficient workflows and tools that empower a lean legal team to excel in commercial agreements, data management, and vendor oversight, driving success in a fast...

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $120K *

Engage in strategic pipeline development to drive revenue across LATAM and North America. Utilize consultative selling and AI tools to connect with technical decision-makers, ensuring high-quality out...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $250K *

Unlock potential by joining a dynamic sales team focused on energy efficiency. Engage with homeowners, conduct assessments, and recommend upgrades in a rewarding environment with no cold calling and s...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$95K - $250K *

Grow your career with a dynamic sales role focused on energy efficiency. Engage homeowners through pre-qualified appointments, conduct assessments, and recommend upgrades in a fast-paced, rewarding en...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$75K - $150K *

Champion the management of Low-Income Housing Tax Credit investments, overseeing asset performance and risk assessment throughout the investment lifecycle. Collaborate with stakeholders to ensure stra...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Empower your career by building innovative ML systems that transform messy scientific data into actionable insights. Collaborate with engineers and scientists to tackle complex AI challenges in real-w...

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Accelerate progress at a dynamic Retail Media organization by driving new business, developing strategies, and fostering client relationships. This hands-on role requires strong digital media expertis...

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Drive your career forward by developing cutting-edge control planes for AI infrastructure. Collaborate with a dynamic team to enhance cloud-native orchestration platforms, leveraging your expertise in...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $165K *

Elevate public sector solutions by designing and delivering scalable Salesforce applications. Collaborate with cross-functional teams to enhance operational efficiency and modernize processes, ensurin...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Elevate your career by overseeing transportation operations across five distribution centers, optimizing strategies, and enhancing service levels while managing costs to ensure excellence in our logis...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$220K - $290K *

Champion the development and delivery of advanced embedded software for autonomous systems, leading a multidisciplinary engineering team to ensure high-quality, reliable software solutions that enhanc...

3 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.