Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$85K - $110K *

Join a dynamic team to drive innovative sales solutions in higher education. Leverage your expertise to identify learner needs and exceed sales goals through a blend of in-house and field work, foster...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $222K *

Optimize valuation processes for complex securities, ensuring accuracy and compliance. Oversee third-party relationships, manage junior associates, and collaborate across teams to enhance operational...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the charge in managing supply chain and logistics operations, ensuring accurate inventory control and timely shipments. Collaborate with internal and external partners to optimize processes and s...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate clinical research by monitoring trials, ensuring compliance with protocols and regulations. Collaborate with investigators to achieve study goals in dermatology and rheumatology, while working...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $159K *

Elevate our global governance, risk, and compliance programme by leading risk assessments, policy governance, and audit support. Collaborate with cross-functional teams to ensure compliance with ISO 2...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K *

Join a team that drives new business growth through client engagement and software solutions. As an Account Executive, you'll build relationships, consult on software needs, and contribute to expandin...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$32K - $137K *

Unlock your potential by guiding clients through financial challenges. Manage inbound calls with a consultative approach, build trust, and exceed performance goals in a supportive, remote environment...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Unlock potential by driving accurate revenue reporting and enhancing processes. As a Senior Revenue Accountant, you'll collaborate across teams to ensure compliance with ASC 606 while supporting audit...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Lead cost estimating processes to support manufacturing projects, driving accurate budgeting and forecasts while collaborating with integrated product teams on defense-related initiatives...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$85K - $113K *

Join our team to empower evidence-based decision-making through effective Monitoring, Evaluation, and Learning (MEL) strategies. Collaborate globally to enhance health programs and ensure quality data...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Unlock potential by driving new logo acquisition in a greenfield territory. Manage the entire sales cycle, build lasting relationships, and shape the future of revenue intelligence as a founding membe...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $159K *

Drive the transformation of AI agent capabilities into scalable, revenue-generating products. Collaborate across teams to define strategies, evaluate opportunities, and lead product commercialization...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $185K *

Drive the future of factory design by leading comprehensive programs from concept to operational handoff, ensuring alignment with business objectives and stakeholder engagement throughout the project...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$99K - $232K *

Transform banking operations by leading testing strategy and execution for core technology platforms. Drive quality assurance, mentor teams, and enhance systems through analysis and innovation while m...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$142K - $284K *

Champion growth initiatives by analyzing market trends and synthesizing insights to drive strategic priorities. Collaborate with cross-functional teams to simplify complex challenges and enhance healt...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K *

Elevate your career by providing clinical support and training for patient monitoring systems. Lead implementation teams, ensure customer satisfaction, and maintain clinical expertise while managing t...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $143K *

Optimize your career by developing and executing clinical marketing strategies that enhance customer engagement and drive adoption of innovative patient monitoring solutions. Collaborate with cross-fu...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$59K - $105K *

Join a dynamic team as an Intervention Specialist, providing targeted support to enhance academic success for 9th and 10th graders in ELA and Mathematics. Collaborate with educators to implement data...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$130K - $150K *

Transform your career by leveraging your AWS expertise in a dynamic DevOps role. Collaborate with a hands-on team to enhance infrastructure and streamline development processes while tackling complex...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$68K - $103K *

Join a team that's enhancing clinical research by drafting and negotiating diverse agreements, ensuring compliance with timelines, and collaborating with global stakeholders to achieve successful proj...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Optimize the promotional review process by coordinating cross-functional workflows, ensuring compliance, and facilitating timely approvals of marketing materials. Collaborate with internal and externa...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $127K *

Transform your career by owning strategic lifecycle marketing initiatives that drive revenue growth. Collaborate cross-functionally to optimize customer journeys and enhance user experiences through d...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$207K - $267K *

Unlock potential by leading global procurement strategies, optimizing vendor management, and driving efficiency across technology and software categories while mentoring a high-performing team...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Media

$100K - $105K *

Lead the charge in operational excellence as you oversee CCAPE's programs, ensuring quality delivery and strategic alignment. Collaborate with teams to enhance workforce development initiatives and em...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$132K - $251K *

Lead the charge in developing advanced airborne EO/IR sensor systems, ensuring mission success through technical leadership, system design, and collaboration across engineering functions while mentori...

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.