Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$75K - $84K *

Join a team that's dedicated to supporting our nation's nuclear submarine fleet by repairing and maintaining critical electronic and mechanical components. Collaborate with cross-functional experts to...

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$46K - $122K *

Join a team that's redefining healthcare contracts by leveraging financial expertise and strategic negotiation skills to enhance client relationships and drive business success in a dynamic environmen...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $135K *

Optimize industrial engineering models to enhance factory planning and operations. Drive efficiency through data analysis, scenario planning, and collaboration across teams. Present insights to leader...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Lead cross-functional projects in health plan relations, enhancing revenue cycle performance and outcomes. Utilize strong communication and project management skills to coordinate initiatives, track p...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$54K - $155K *

Lead the charge in telephonic case management, collaborating with patients and care teams to support quality healthcare delivery. Use clinical expertise to assess needs, implement strategies, and ensu...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Engage in strategic leadership to enhance wholesale market placements, ensuring optimal coverage and pricing. Oversee national partnerships and market execution while driving team performance and resp...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$80K - $95K *

Analyze and evaluate AI-generated chatbot responses to enhance accuracy and relevance. Collaborate with stakeholders to document requirements and deliver structured assessments that drive improvements...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Staffing

$160K *

Drive enterprise-level implementations of phishing-resistant authentication solutions, leading technical deployments and integrations across various identity platforms while ensuring customer success...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $180K *

Lead strategic health plan implementations and optimize client solutions. Drive cross-functional collaboration, manage complex projects, and enhance operational workflows to ensure successful launches...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $176K *

Lead the design and development of complex PCBs for advanced instrumentation systems, collaborating with multidisciplinary teams to deliver high-performance hardware solutions from concept through pro...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$179K - $236K *

Unlock your potential by joining a dynamic team focused on scaling innovative cellular biology solutions, driving impactful advancements in medicine and patient care through cutting-edge technology an...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Shape your career as you take ownership of key accounts, driving sales and building relationships. Collaborate with top performers to modernize government services, while gaining invaluable experience...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Drive business growth by assessing market opportunities, developing strategies, and delivering compelling presentations. Collaborate with teams to align marketing efforts and support client proposals...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Unlock potential by leading diverse airport planning projects, ensuring compliance with FAA regulations, and collaborating with stakeholders to deliver innovative solutions in a dynamic environment...

3 days ago

  •   5 - 7 years exp.  •   Transportation

$100K - $150K *

Lead the charge in managing complex, technically sophisticated projects, focusing on data centers. Collaborate with diverse stakeholders to ensure project alignment with client goals, budgets, and sch...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $301K *

Shape the future of health actuarial consulting by leading diverse teams, managing complex projects, and driving innovative solutions for government programs while adhering to federal regulations and...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$105K - $150K *

Inspire impactful change by leading complex federal digital services programs. Oversee strategy, execution, and customer relationships while managing multidisciplinary teams to deliver high-quality te...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $300K *

Join a team that's driving innovation in digital engagement solutions for the pharmaceutical industry. As an Account Partner, you'll lead sales efforts, build relationships, and deliver impactful AI-p...

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $180K *

Lead the product vision and strategy for a cutting-edge cloud service, shaping capabilities and defining AI-driven insights while collaborating with engineering and operations teams to ensure market a...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Explore a pivotal HR leadership role blending Business Partnering with Total Rewards Analytics. Drive talent effectiveness and strategic insights to enhance compensation, workforce planning, and organ...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join a team that's shaping evidence strategies and insights in health economics and outcomes research. Lead client engagements, oversee analytics, and drive impactful decision-making in biopharma and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $145K *

Join a team that's dedicated to ensuring accurate and compliant payroll operations statewide. Lead and mentor payroll professionals while promoting best practices and accountability across departments...

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$100K - $105K *

Empower families by leading a dynamic Early Intervention Program, ensuring compliance and quality service delivery for infants and toddlers. Drive operational excellence and foster community partnersh...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $160K *

Elevate our global paid acquisition strategies by optimizing Google Ads campaigns. As a hands-on performance marketer, you'll manage budgets, drive measurable results, and leverage data to enhance gro...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$75K - $90K *

Help us drive operational excellence by leading assembly operations, developing standardized processes, and fostering cross-functional collaboration to ensure efficient, high-quality production and co...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.