Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$120K - $225K *

Grow your career with a senior role in enterprise architecture, shaping technology direction and governance. Collaborate with leaders to develop strategies that drive innovation, reduce complexity, an...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Join a dynamic team as you shape enterprise architecture strategies, drive innovation, and optimize technology governance. Collaborate with senior leaders to align business outcomes with technology di...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Join a team that's shaping the future of data architecture. In this senior role, you'll develop strategies and standards that drive enterprise-level data governance, analytics, and AI capabilities, en...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Lead the charge in shaping enterprise architecture strategies and governance, collaborating with senior stakeholders to drive technology innovation, reduce complexity, and optimize costs across platfo...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Shape the future of technology by developing enterprise architecture strategies, guiding platform evolution, and ensuring alignment with business goals. Collaborate with senior leaders to drive innova...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $180K *

Elevate your career by leading the design and development of scalable software solutions for investment performance measurement. Collaborate with cross-functional teams to drive innovation and enhance...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Drive impactful initiatives by leveraging your expertise in finance and analytics. Collaborate across teams to enhance strategies and deliver exceptional results, while fostering a culture of innovati...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $180K *

Elevate your career by leading systems analysis initiatives, driving strategic solutions, and collaborating across teams to enhance operational efficiency and effectiveness in a dynamic environment...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $225K *

Shape the future of investment management by driving innovative strategies and solutions. Collaborate with diverse teams to enhance client experiences and optimize performance across various portfolio...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$138K - $190K *

Join us to shape innovative strategies that drive consumer-centered growth and business differentiation. Collaborate across teams to develop, pilot, and scale impactful initiatives that enhance experi...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$97K - $133K *

Innovate by designing and developing cutting-edge AI solutions using LLMs. Collaborate with cross-functional teams to integrate AI into healthcare systems, ensuring responsible practices and impactful...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$172K - $236K *

Join us to lead the transformation of enterprise architecture, guiding a team to align technical solutions with business goals while ensuring compliance and enhancing consumer experiences across multi...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$94K - $130K *

Elevate product outcomes by collaborating with teams to prioritize and define user stories, ensuring alignment with business needs while maximizing value delivery and maintaining product quality throu...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Join us in driving strategic sales initiatives and optimizing operational performance. This role requires strong project management and analytical skills to enhance sales effectiveness and support mar...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $97K *

Transform patient care by guiding transitions and ensuring optimal service continuity. Leverage your nursing expertise to navigate healthcare options and advocate for patients in need of post-acute se...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $121K *

Shape the future of data-driven decision-making by leveraging diverse technologies to enhance business insights and process automation. Collaborate with stakeholders to deliver impactful solutions wit...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$168K - $268K *

Join a team that's shaping legal strategies for business units, providing expert advice on contracts, compliance, and regulatory matters. Collaborate with multidisciplinary teams to align legal soluti...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$121K - $174K *

Join a dynamic team to support sales activities and enhance customer relations in the clinical setting. Drive product penetration and collaborate with internal teams to achieve business objectives and...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$98K - $163K *

Support audit remediation initiatives by coordinating with stakeholders, analyzing findings, and developing strategies to enhance audit readiness and internal controls, ensuring effective communicatio...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$77K - $129K *

Unlock your potential as a Business Analyst, driving Agile software development efforts for diverse health industry projects, collaborating closely with stakeholders to deliver high-quality, scalable...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Business Services

$74K - $124K *

Lead audit remediation initiatives by coordinating with stakeholders, analyzing findings, and developing strategies to enhance internal controls and audit readiness, ensuring successful outcomes for f...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$85K - $141K *

Analyze loan files to ensure compliance with SBA requirements, identifying risks and deficiencies. Collaborate with lenders to clarify documentation and prepare detailed reports, maintaining high stan...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$113K - $188K *

Transform client operations by delivering innovative solutions using Microsoft Power Platform. Lead implementations, automate processes, and ensure high-quality development while collaborating with st...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$98K - $163K *

Analyze and support federal clients in oversight and monitoring of grant programs, ensuring program integrity and accountability. Collaborate with stakeholders to assess risks, develop recommendations...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$206K - $343K *

Transform your career by leading AI & Data initiatives for Energy Providers. Drive growth, build client relationships, and develop a high-performing team while delivering innovative solutions that add...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.