Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$46K - $128K *

Partner with us to support environmental compliance and safety initiatives. This entry-level role involves collaborating with stakeholders to ensure regulatory adherence, risk assessment, and continuo...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$79K - $115K *

Empower our financial planning team by optimizing analytics platforms and enhancing reporting tools. Collaborate across departments to deliver actionable insights and drive efficiency through technolo...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$135K - $173K *

Elevate your career by providing comprehensive care to patients with gynecologic malignancies. Collaborate with a dedicated team to assess, manage, and support patients through their treatment journey...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$247K - $305K *

Support the strategic commercialization of rare disease therapies by leading marketing initiatives, collaborating cross-functionally, and optimizing brand strategies to enhance patient access and enga...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$65K - $104K *

Transform patient care by delivering high-quality radiologic services in a dynamic urgent care setting. Collaborate with a dedicated team to ensure accurate diagnoses and compassionate support for pat...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$121K - $202K *

Shape the future of performance engineering by leading QA delivery for high-transaction healthcare platforms. Drive strategy, mentor teams, and enhance the reliability and scalability of critical syst...

RemoteRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $115K *

Transform the marketing landscape by leveraging consumer insights and cultural trends to drive brand engagement and relevance. Collaborate across teams to create impactful initiatives that resonate wi...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$206K - $250K *

Unlock potential by serving as a key legal partner, managing complex pharmaceutical agreements, and collaborating across teams to provide practical legal guidance while navigating business needs and r...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$78K - $105K *

Transform patient care by providing essential infusion therapy in a dynamic oncology setting. Collaborate with a multidisciplinary team to enhance patient experiences and outcomes while adhering to be...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$190K - $230K *

Elevate drug discovery efforts by leading multidisciplinary teams in immune signaling research, from hit identification to IND submission, while balancing hands-on lab work and strategic program manag...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$103K - $136K *

Optimize complex casualty claims management by investigating, negotiating, and resolving high-severity cases while ensuring compliance and effective communication with stakeholders to achieve favorabl...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$175K - $210K *

Unlock potential by leading HEOR strategy and AI integration, ensuring project success and client satisfaction. Drive business growth, mentor teams, and influence health policy through innovative rese...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$206K - $309K *

Elevate the Analyst Experience by owning strategy and outcomes for security workflows. Lead a team of product managers to unify analyst tools, drive customer migrations, and enhance product vision, en...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$67K - $109K *

Shape the future of retail media by managing end-to-end campaign execution, collaborating with sales and internal teams to drive strategic growth and deliver impactful insights for brand partners...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$127K - $161K *

Manage and execute environmental compliance initiatives across multiple sites, ensuring adherence to regulations and fostering a culture of sustainability. Collaborate with leadership to drive continu...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Lead impactful B2B paid media strategies, optimizing campaigns for top clients. Drive performance, enhance client relationships, and deliver insightful analysis while managing multiple accounts in a f...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$170K - $200K *

Shape the future of international financial reporting by leading statutory and sustainability reporting for global entities, ensuring compliance and accuracy while collaborating with cross-functional...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$75K - $100K *

Elevate your career by joining our team of therapists, offering flexible schedules and a supportive environment. Enjoy autonomy in your practice while providing essential mental health services throug...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $170K *

Join a team that's redefining product strategy through advanced analytics. Leverage your expertise to drive insights, enhance product performance, and collaborate with stakeholders to make impactful b...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$148K - $186K *

Elevate progress at our People Technology Team by leading Workday delivery, managing vendor relationships, and driving strategic solutions. Collaborate with stakeholders to enhance platform usage and...

Boston, MARemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $120K *

Join a dynamic team as you drive integrated care management for dually-eligible enrollees. Engage with diverse populations, coordinate health services, and enhance quality of life through holistic car...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $186K *

Elevate your career by leading the Workday enterprise platform, driving transformation, and fostering proactive delivery of employee-centered solutions through strong people leadership and technical e...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$84K - $148K *

Lead the charge in optimizing mainframe database environments, ensuring seamless upgrades, administration, and performance tuning. Collaborate with vendors and support clients with 24x7 on-call assist...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $155K *

Join a dynamic team to support satellite systems engineering and operations, ensuring optimal performance and maintenance of satellite communications in challenging environments, including annual depl...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$150K - $180K *

Transform the architecture of diverse security platforms, guiding teams through complex design challenges while ensuring scalable, secure, and maintainable systems across multiple product areas in a h...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.