Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.
Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.
Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.
Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.
Average Salary: $126,017
Lead, Sales & Operations Execution Process (Billerica, MA)
$101K - $140K *
Join a dynamic team to lead and enhance the Sales and Operations Execution process, ensuring seamless integration across functions. Drive timely decisions and actions to mitigate risks and improve ope...
3 days ago
Program Manager (Department Manager)
$95K - $115K *
Lead the charge in optimizing departmental operations by defining goals, managing resources, and enhancing compliance outcomes. Drive strategic initiatives and foster team development to achieve organ...
3 days ago
$88K - $105K *
Drive system administration excellence by managing Windows servers, ensuring compliance, and automating processes. Collaborate with teams to enhance infrastructure and support key technology initiativ...
3 days ago
Sr. Manager, Finance & Strategy
$170K - $220K *
Unlock potential by joining a dynamic team focused on strategic finance and operational excellence. Drive impactful analyses and reporting to enhance decision-making across Sales, Customer Success, an...
3 days ago
Treasury BIA Manager (Remote - CA)
$142K - $188K *
Empower your career by leading Treasury's analytics framework, optimizing workflows, and enhancing data governance. Collaborate with stakeholders to drive digital transformation and support data-drive...
3 days ago
Associate Sales Representative - JR- Boston, MA
$72K - $90K *
Elevate your career by supporting a dynamic sales team in promoting innovative medical products. Engage with clients, conduct evaluations, and enhance your sales skills while delivering exceptional cu...
3 days ago
Chief Information Security Officer
$260K - $330K *
Transform enterprise security strategy and governance in a high-growth healthcare AI environment. Collaborate with leadership to embed security across products and operations, ensuring compliance and...
3 days ago
$90K - $110K *
Unlock potential by driving new business sales in a dynamic, AI-enabled environment. Own your territory, create a robust pipeline, and engage sophisticated buyers to deliver consistent revenue growth...
3 days ago
Strategic Partner Director, Channel Sales
$150K - $180K *
Shape the future of financial partnerships by driving revenue through strategic alliances with banks and fintechs. Collaborate cross-functionally to enhance Socure's market presence and ensure seamles...
3 days ago
Postdoctoral Scientist - Neuroscience (Synuclein Biology)
$58K - $123K *
Join a dynamic team to investigate molecular mechanisms of α-synuclein aggregation and dysfunction, advancing therapeutic strategies for neurodegenerative diseases through innovative experimentation a...
Reposted 3 days ago
$150K - $184K *
Lead the charge in enhancing platform security and infrastructure as a Senior Software Engineer. Utilize your Python expertise and SRE mindset to drive critical improvements, mentor teammates, and ens...
3 days ago
Principal Engineer - Application Architecture
$107K - $216K *
Lead the charge in architecting a cloud-native SaaS platform, driving technical vision and standards while collaborating with cross-functional teams to deliver innovative solutions in the charitable s...
3 days ago
$84K - $109K *
Join the forefront of astronomical research, confirming and characterizing exoplanets through advanced data analysis and collaboration with NASA's TESS mission. Engage in original research and contrib...
3 days ago
Manager of Bioinformatics (Oncology Product Development)
$140K - $175K *
Lead the charge in advancing oncology diagnostics by managing a team of bioinformaticians and data scientists, driving product development, and ensuring high-quality analysis and validation of ctDNA-b...
3 days ago
$80K - $90K *
Grow your career with a dynamic team in tax solutions for high-net-worth clients, delivering integrated planning and compliance services while honing your expertise through mentorship and collaboratio...
Reposted 3 days ago
Sales & Business Development Manager
$85K *
Lead and develop a high-performing SDR team to enhance sales pipeline efficiency, ensuring timely responses and quality prospect engagement through data-driven strategies and collaborative processes w...
3 days ago
Growth Sales Account Executive
$84K - $96K *
Champion customer success by managing and expanding a territory of existing accounts. Drive renewals and upsells through strategic outreach, relationship building, and leveraging partnerships to enhan...
3 days ago
Electrical Manager High Voltage- Data Center - 100% Travel
$100K - $120K *
Lead the charge in managing electrical installations for utility-scale solar projects. Oversee contractor coordination, ensure quality control, and foster strong relationships while navigating a dynam...
3 days ago
Electrical Engineer II - Digital Design Engineer
$68K - $131K *
Analyze and develop digital electronic designs and systems, ensuring robust integration and performance through collaboration with cross-functional teams in a challenging environment. Enhance system r...
Reposted 3 days ago
Senior UX Researcher, Quantitative
$120K - $145K *
Lead quantitative user research across product lines, shaping strategy and answering critical questions with data-driven insights. Collaborate with teams to prioritize research that mitigates risk and...
3 days ago
Electrical Engineer II - Digital Design Engineer
$68K - $131K *
Contribute to the design and integration of innovative digital electronic systems, ensuring high-quality performance across various environments. Collaborate closely with cross-functional teams to mee...
Reposted 3 days ago
$88K - $121K *
Empower healthcare teams by providing clinical support and training for vital sign and cardiology products. Collaborate with sales and customers to enhance product use and ensure educational goals are...
3 days ago
$119K - $149K *
Lead full-cycle recruiting for technical and analytical roles, partnering with teams to define success and build diverse talent pipelines. Utilize creative sourcing and data-driven insights to enhance...
3 days ago
$100K - $130K *
Lead comprehensive Medical Loss Ratio examinations, ensuring compliance with ACA regulations. Oversee examiners, manage communications, and analyze data to deliver accurate results. Work remotely in a...
3 days ago
$46K - $128K *
Join the Environmental and Safety Engineering team to support compliance, risk assessment, and sustainability initiatives. This entry-level role offers hands-on experience in environmental engineering...
3 days ago
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.
Where in Massachusetts can I find high-paying jobs?
Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.
How can I search for Massachusetts jobs paying $100,000 or more?
Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.
Are Massachusetts jobs on Ladders vetted?
Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.