Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$101K - $140K *

Join a dynamic team to lead and enhance the Sales and Operations Execution process, ensuring seamless integration across functions. Drive timely decisions and actions to mitigate risks and improve ope...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Lead the charge in optimizing departmental operations by defining goals, managing resources, and enhancing compliance outcomes. Drive strategic initiatives and foster team development to achieve organ...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$88K - $105K *

Drive system administration excellence by managing Windows servers, ensuring compliance, and automating processes. Collaborate with teams to enhance infrastructure and support key technology initiativ...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $220K *

Unlock potential by joining a dynamic team focused on strategic finance and operational excellence. Drive impactful analyses and reporting to enhance decision-making across Sales, Customer Success, an...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$142K - $188K *

Empower your career by leading Treasury's analytics framework, optimizing workflows, and enhancing data governance. Collaborate with stakeholders to drive digital transformation and support data-drive...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$72K - $90K *

Elevate your career by supporting a dynamic sales team in promoting innovative medical products. Engage with clients, conduct evaluations, and enhance your sales skills while delivering exceptional cu...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$260K - $330K *

Transform enterprise security strategy and governance in a high-growth healthcare AI environment. Collaborate with leadership to embed security across products and operations, ensuring compliance and...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $110K *

Unlock potential by driving new business sales in a dynamic, AI-enabled environment. Own your territory, create a robust pipeline, and engage sophisticated buyers to deliver consistent revenue growth...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Shape the future of financial partnerships by driving revenue through strategic alliances with banks and fintechs. Collaborate cross-functionally to enhance Socure's market presence and ensure seamles...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$58K - $123K *

Join a dynamic team to investigate molecular mechanisms of α-synuclein aggregation and dysfunction, advancing therapeutic strategies for neurodegenerative diseases through innovative experimentation a...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $184K *

Lead the charge in enhancing platform security and infrastructure as a Senior Software Engineer. Utilize your Python expertise and SRE mindset to drive critical improvements, mentor teammates, and ens...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$107K - $216K *

Lead the charge in architecting a cloud-native SaaS platform, driving technical vision and standards while collaborating with cross-functional teams to deliver innovative solutions in the charitable s...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$84K - $109K *

Join the forefront of astronomical research, confirming and characterizing exoplanets through advanced data analysis and collaboration with NASA's TESS mission. Engage in original research and contrib...

3 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$140K - $175K *

Lead the charge in advancing oncology diagnostics by managing a team of bioinformaticians and data scientists, driving product development, and ensuring high-quality analysis and validation of ctDNA-b...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $90K *

Grow your career with a dynamic team in tax solutions for high-net-worth clients, delivering integrated planning and compliance services while honing your expertise through mentorship and collaboratio...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K *

Lead and develop a high-performing SDR team to enhance sales pipeline efficiency, ensuring timely responses and quality prospect engagement through data-driven strategies and collaborative processes w...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$84K - $96K *

Champion customer success by managing and expanding a territory of existing accounts. Drive renewals and upsells through strategic outreach, relationship building, and leveraging partnerships to enhan...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Lead the charge in managing electrical installations for utility-scale solar projects. Oversee contractor coordination, ensure quality control, and foster strong relationships while navigating a dynam...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$68K - $131K *

Analyze and develop digital electronic designs and systems, ensuring robust integration and performance through collaboration with cross-functional teams in a challenging environment. Enhance system r...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$120K - $145K *

Lead quantitative user research across product lines, shaping strategy and answering critical questions with data-driven insights. Collaborate with teams to prioritize research that mitigates risk and...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$68K - $131K *

Contribute to the design and integration of innovative digital electronic systems, ensuring high-quality performance across various environments. Collaborate closely with cross-functional teams to mee...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$88K - $121K *

Empower healthcare teams by providing clinical support and training for vital sign and cardiology products. Collaborate with sales and customers to enhance product use and ensure educational goals are...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $149K *

Lead full-cycle recruiting for technical and analytical roles, partnering with teams to define success and build diverse talent pipelines. Utilize creative sourcing and data-driven insights to enhance...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $130K *

Lead comprehensive Medical Loss Ratio examinations, ensuring compliance with ACA regulations. Oversee examiners, manage communications, and analyze data to deliver accurate results. Work remotely in a...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$46K - $128K *

Join the Environmental and Safety Engineering team to support compliance, risk assessment, and sustainability initiatives. This entry-level role offers hands-on experience in environmental engineering...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.