Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$150K - $220K *

Unlock potential by leading agent acquisition efforts to drive growth, enhance sales processes, and optimize recruitment strategies. Collaborate with teams to build a high-performing sales organizatio...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Media

$160K - $170K *

Elevate data engineering excellence by designing and implementing complex data solutions, mentoring engineers, and collaborating across teams to drive impactful data initiatives and architectural inno...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$88K - $105K *

Lead the charge in managing client relationships and project execution, ensuring timely delivery and quality outcomes across multiple projects while supervising team members and maintaining budgetary...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $140K *

Join the charge in advancing biotechnology research, executing projects that impact health care investments while collaborating with a skilled team to leverage your analytical expertise and effective...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $150K *

Transform accounting operations by bridging customer workflows and AI-driven solutions. Engage in pre-sale discovery, design automated solutions, and ensure accurate implementation, all while collabor...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $140K *

Advance your career by driving AI-enabled operational excellence, enhancing performance metrics, and leading cross-functional initiatives to optimize workflows and member experience in a dynamic busin...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$80K - $95K *

Advance compliance operations by conducting transaction monitoring, investigating suspicious activities, and collaborating cross-functionally to ensure regulatory adherence in a dynamic digital asset...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $200K *

Lead the charge in defining GTM Engineering at Omnissa, shaping the vision, roadmap, and systems to enhance efficiency across Sales, Marketing, and Customer Success. Drive innovation and ownership in...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Drive integration excellence by designing and supporting seamless data exchanges between Oracle HCM Cloud and enterprise systems, leveraging your expertise in OIC, APIs, and SQL to enhance HR operatio...

4 days ago

  •   5 - 7 years exp.  •   Staffing

$118K - $131K *

Join a team that's driving innovation in guidance systems through analysis, design, and testing. Collaborate on cutting-edge projects while advancing technology in a dynamic environment focused on nat...

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$75K - $110K *

Elevate progress at the forefront of neuroscience by annotating and proofreading 3D microscopy volumes. Collaborate with scientists and engineers to refine protocols and tools, ensuring high-quality d...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$96K - $148K *

Transform the chromatography marketing landscape by driving global strategies that enhance brand visibility, stimulate demand, and foster revenue growth through collaboration, innovative campaigns, an...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $108K *

Drive client success by managing complex employee benefit programs, ensuring compliance, and delivering strategic insights. Collaborate with internal teams to enhance client relationships and satisfac...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $108K *

Champion client relationships by managing complex employee benefit programs, driving strategic renewals, and delivering exceptional service. Leverage advanced expertise to enhance client satisfaction...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$124K - $158K *

Take ownership of pharmacy operations, ensuring safe dispensing and patient care while leading a dedicated team. Collaborate with management to enhance performance and compliance, delivering exception...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$124K - $158K *

Join a dynamic team as you lead pharmacy operations, ensuring safe dispensing and patient care while mentoring staff and enhancing pharmacy performance. Drive positive patient experiences through comp...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Unlock potential by delivering innovative LIMS solutions in regulated labs. Collaborate with global teams to enhance data integrity and operational efficiency while managing the full sample lifecycle...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$101K - $203K *

Take ownership of our Azure Databricks platform, enhancing data ingestion, quality, and security. Collaborate with teams to streamline operations, implement CI/CD practices, and ensure reliability in...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$99K - $232K *

Lead the charge in core banking modernization, guiding teams through transformation initiatives while enhancing operational efficiency and client relationships in a dynamic advisory environment...

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$158K - $253K *

Join a team that's redefining high-speed digital and optical solutions. Lead a multidisciplinary engineering group, driving innovation from technology evaluation to production, while collaborating wit...

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$136K - $211K *

Drive innovative research by connecting physiological signals to human outcomes. Collaborate with teams to design studies, build models, and enhance measurement quality, all while leveraging AI tools...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$250K - $400K *

Shape the future of AI by partnering with customers to design and deliver innovative data solutions. Collaborate with a senior team to tackle complex challenges and transform vague requests into actio...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Unlock potential by driving commercial growth strategies for a product family. Collaborate across teams to translate market insights into actionable plans that enhance revenue, profitability, and cust...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$77K - $100K *

Lead daily patient dining operations, enhancing service quality and team engagement while ensuring compliance and operational efficiency. Drive patient satisfaction initiatives and foster a culture of...

4 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$77K - $100K *

Lead the charge in culinary excellence by standardizing operations, mentoring teams, and crafting innovative menus that enhance client experiences while driving continuous improvement and fostering st...

4 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.