Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$200K - $250K *

Elevate the search experience by designing and evolving a robust backend system that powers millions of searches. Collaborate across teams to enhance scalability, reliability, and maintainability whil...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$138K - $219K *

Transform credit strategy by leading complex commercial credit relationships, mentoring junior professionals, and ensuring portfolio health through innovative deal structuring and proactive risk manag...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$122K - $212K *

Transform your career by leading investigations that ensure quality and compliance within the medical device industry. Collaborate with cross-functional teams to drive improvements and reduce risks, a...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $180K *

Lead organizational capability by bridging strategy and execution across diverse hospitality operations. Drive scalable frameworks and change management to enhance performance and sustain innovation a...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$302K - $483K *

Transform the future of secure platforms by leading engineering strategy and execution. Drive innovation, operational excellence, and team performance to empower autonomy and accountability across the...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Lead the charge in expanding our retail network by identifying and securing new business partnerships. This high-performance role requires a hunter mentality, resilience, and the ability to drive grow...

4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$250K - $300K *

Take ownership of a dynamic automotive dealership, driving sales and service excellence while fostering customer relationships and leading a motivated team to achieve operational success and complianc...

4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$220K - $310K *

Empower businesses by architecting and deploying innovative AI solutions that leverage graph databases and LLMs. Collaborate with stakeholders to transform complex data challenges into impactful appli...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Unlock potential by designing and building robust data pipelines for healthcare transactions. Collaborate with partners to ensure seamless integration and reliability of data systems, enhancing operat...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $118K *

Lead the charge in managing curriculum adoptions, collaborating with stakeholders to ensure successful outcomes in K-12 education. Elevate adoption processes and quality, supporting cross-functional t...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$82K - $174K *

Join our team to deliver exceptional nursing care through assessment, planning, and execution of individualized patient care plans. Collaborate with healthcare professionals to ensure safety, quality...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $140K *

Grow your career with us by leading public safety drone sales in small cities. Own your territory, drive full-cycle deals, and collaborate with cross-functional teams to deliver innovative solutions t...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$152K - $223K *

Drive operational transformation and cloud readiness by leading database modernization initiatives, improving reliability and engineering excellence through automation and best practices while mentori...

RemoteRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$60K - $110K *

Lead a dynamic team to oversee store remodels and new projects nationwide. Ensure timely, budget-friendly execution while fostering collaboration and development among associates. Travel frequently to...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$225K - $300K *

Unlock potential by leading a dynamic sales team to drive financial success and enhance customer experiences in a high-volume automotive environment. Your leadership will redefine the car-buying journ...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Drive strategic planning and operational excellence for a dynamic Marketing & Communications team. Own budgeting, resource management, and cross-functional partnerships while leading initiatives that...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $180K *

Shape the future of scientific software by owning quality for critical use cases, ensuring compliance, and driving automation. Collaborate with diverse teams to enhance testing processes and deliver h...

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$78K - $108K *

Empower our growth by managing and negotiating sales contracts, collaborating with cross-functional teams to ensure compliance and efficiency. Your expertise will drive impactful solutions in a dynami...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$97K - $117K *

Support analytical method lifecycle management, instrument qualification, and compliance across GMP operations. Collaborate with cross-functional teams to ensure effective and compliant analytical sys...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $160K *

Join a dynamic team as a Sr. Health Benefit Plan Consulting Attorney, leveraging your expertise in healthcare law to navigate complex regulatory issues, support consulting services, and drive complian...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $97K *

Elevate your career by leveraging data science to drive strategic insights and business decisions. Collaborate with cross-functional teams to develop innovative models and visualizations that enhance...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $90K *

Manage and analyze Lost-Time Workers Compensation claims, ensuring timely resolution and adherence to service expectations. Collaborate with clients and stakeholders to deliver innovative solutions in...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$131K - $170K *

Accelerate your career by driving manufacturing process improvements, collaborating with teams to enhance safety, quality, and efficiency in a capital equipment-intensive environment. Engage in troubl...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$140K - $160K *

Elevate product collaboration by leading the development of a cloud-based solution. Drive customer insights into actionable priorities, collaborating with cross-functional teams to ensure successful p...

4 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$66K - $102K *

Optimize client solutions by leveraging SAP FICO expertise to analyze, design, and implement financial processes. Collaborate with teams to enhance system functionality and ensure seamless integration...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.