Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$150K - $180K *

Drive strategic planning and operational excellence for a dynamic Marketing & Communications team. Own budgeting, resource management, and cross-functional partnerships while leading initiatives that...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $180K *

Shape the future of scientific software by owning quality for critical use cases, ensuring compliance, and driving automation. Collaborate with diverse teams to enhance testing processes and deliver h...

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$78K - $108K *

Empower our growth by managing and negotiating sales contracts, collaborating with cross-functional teams to ensure compliance and efficiency. Your expertise will drive impactful solutions in a dynami...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$97K - $117K *

Support analytical method lifecycle management, instrument qualification, and compliance across GMP operations. Collaborate with cross-functional teams to ensure effective and compliant analytical sys...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $160K *

Join a dynamic team as a Sr. Health Benefit Plan Consulting Attorney, leveraging your expertise in healthcare law to navigate complex regulatory issues, support consulting services, and drive complian...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $97K *

Elevate your career by leveraging data science to drive strategic insights and business decisions. Collaborate with cross-functional teams to develop innovative models and visualizations that enhance...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $90K *

Manage and analyze Lost-Time Workers Compensation claims, ensuring timely resolution and adherence to service expectations. Collaborate with clients and stakeholders to deliver innovative solutions in...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$131K - $170K *

Accelerate your career by driving manufacturing process improvements, collaborating with teams to enhance safety, quality, and efficiency in a capital equipment-intensive environment. Engage in troubl...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$140K - $160K *

Elevate product collaboration by leading the development of a cloud-based solution. Drive customer insights into actionable priorities, collaborating with cross-functional teams to ensure successful p...

4 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$66K - $102K *

Optimize client solutions by leveraging SAP FICO expertise to analyze, design, and implement financial processes. Collaborate with teams to enhance system functionality and ensure seamless integration...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$113K - $150K *

Join a team that's dedicated to patient care by assessing, planning, and implementing individualized treatment plans. Collaborate with healthcare professionals to enhance patient outcomes and support...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$113K - $150K *

Lead the charge in delivering comprehensive patient care through assessment, planning, and implementation of individualized treatment plans. Collaborate with healthcare teams to enhance patient satisf...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$134K - $249K *

Lead the charge in enhancing clinical systems operations, driving efficiency and effectiveness across pharmacy initiatives while managing a dedicated team and overseeing complex workflows and data int...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Take ownership of major fire protection projects, driving execution from planning to closeout. Collaborate with teams to ensure financial performance, quality standards, and safety while managing comp...

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$106K - $159K *

Empower the commercial organization by developing and managing training programs, enhancing onboarding processes, and ensuring alignment across brands. Collaborate with leaders to drive continuous imp...

4 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Take ownership of key client relationships, driving growth in the renewable energy analytics sector while collaborating across teams to support long-term strategic goals and ensure client success with...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$65K - $150K *

Unlock potential by collaborating with cross-functional teams to enhance AI systems. Troubleshoot complex issues, improve performance, and empower users through effective training and support in a dyn...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $205K *

Transform security landscapes by conducting advanced vulnerability assessments and penetration testing. Collaborate with diverse teams to identify, communicate, and remediate risks associated with eme...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $133K *

Join a team that's building and leading a high-performing Business Development group. Drive prospecting strategies, enhance team performance, and collaborate with Sales and Marketing to accelerate pip...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Business Services

$94K - $143K *

Lead the charge in high voltage substation design, collaborating with engineers and designers to create detailed drawings and ensure compliance with standards while mentoring team members and managing...

4 days ago

  •   11 - 15 years exp.  •   Technical Services

$80K - $95K *

Lead a dynamic team of travel therapy recruiters while driving personal production. Champion recruitment strategies, enhance team performance, and ensure alignment with client demands to achieve booki...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Staffing

$80K - $95K *

Join a team that's dedicated to delivering precise radiation therapy treatments, collaborating with oncologists, and ensuring patient safety and comfort while utilizing advanced technology and techniq...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $150K *

Unlock potential by driving hardware security assessments, improving client security postures, and delivering actionable insights. Collaborate with teams and engage directly with clients while enhanci...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Advance configuration management practices to ensure integrity and compliance across all program artifacts. Collaborate with cross-functional teams to support audits, manage data deliverables, and mai...

Reposted 4 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$100K - $120K *

Optimize integration processes by bridging technical gaps between systems. Collaborate with campus IT to ensure seamless data flows, troubleshoot issues, and enhance integration reliability for succes...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.