Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$80K - $150K *

Unlock potential by driving hardware security assessments, improving client security postures, and delivering actionable insights. Collaborate with teams and engage directly with clients while enhanci...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Advance configuration management practices to ensure integrity and compliance across all program artifacts. Collaborate with cross-functional teams to support audits, manage data deliverables, and mai...

Reposted 3 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$100K - $120K *

Optimize integration processes by bridging technical gaps between systems. Collaborate with campus IT to ensure seamless data flows, troubleshoot issues, and enhance integration reliability for succes...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$126K - $211K *

Elevate customer relationships by driving growth within oncology practices. Utilize a consultative approach to align solutions with client objectives and collaborate with internal teams to enhance bus...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $267K *

Champion innovation by leading cross-functional teams to design and deliver scalable, high-performance infrastructure solutions that enhance reliability and efficiency across diverse applications and...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

$92K - $139K *

Take ownership of onsite laboratory operations, driving service excellence and compliance while developing high-performing teams. Collaborate with clients and internal stakeholders to achieve exceptio...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$167K - $226K *

Explore the intersection of machine learning and robotics by developing cutting-edge computer vision systems that enhance robotic perception and sensing capabilities, directly impacting production har...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Optimize event sales and rentals by developing strategic income models, managing a dedicated team, and executing high-quality private events that enhance community engagement and support the theater's...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $220K *

Join a team that's redefining mobile robotics by leading the hardware development of an autonomous platform. You'll oversee electrical architecture, safety certification, and team mentorship, driving...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Champion patient access by providing education and support to patients, caregivers, and healthcare professionals. Collaborate across teams to enhance therapy access and ensure a seamless experience fo...

Waltham, MARemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Join a team that's building from the ground up, shaping the engineering foundation and culture while collaborating closely with leadership to define and deliver innovative products...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Engage with patients and healthcare teams to enhance access to therapies, ensuring a seamless support experience. Collaborate across functions to minimize barriers and drive compliance, while monitori...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $114K *

Elevate client well-being by providing tailored therapy services across various modalities. Collaborate with a dynamic team to create impactful treatment plans and foster personal growth in a flexible...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$500K+*

Join a team that's driving sales success through strategic leadership and collaboration. Oversee resource planning, manage budgets, and coach a team of Regional Sales Managers while achieving revenue...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$250K - $500K+*

Optimize and innovate software kernels for hardware integration, collaborating with ML Research and Hardware Engineering teams to enhance performance and efficiency in cutting-edge technology applicat...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$144K - $170K *

Drive strategic occupancy planning and space management solutions, overseeing a dedicated team to align client needs with effective real estate strategies. Lead initiatives that enhance operational ef...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$65K - $105K *

Join a team that's dedicated to delivering exceptional nutrition care to underserved women. Utilize your skills in counseling, collaboration, and technology to make a meaningful impact in a fully remo...

Massachusetts, USRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $225K *

Elevate infrastructure capabilities by designing and implementing a unified platform that integrates bare-metal servers, storage, and networking for large-scale computation and AI workloads, ensuring...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Champion growth by owning the full sales cycle, educating clients, and driving custom part sourcing for hardware companies. Collaborate with a remote team to deliver exceptional service and build last...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$91K - $321K *

Advance internal investigations focused on ethics and business conduct. Lead complex case work, coach teams, and communicate effectively with stakeholders while ensuring compliance with legal and regu...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$130K - $155K *

Lead the charge in building and scaling a transformative platform for pharma and biopharma, ensuring high-impact outcomes through innovative engineering and collaboration with cross-functional teams...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Transform customer experiences by providing technical expertise and solutions. Collaborate with sales and engineering teams to deliver impactful product demonstrations and address technical challenges...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $182K *

Lead the charge in clinical study management, overseeing strategy and execution for complex trials. Collaborate with cross-functional teams to ensure compliance, budget adherence, and timely delivery...

Massachusetts, USRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $200K *

Join a team that's dedicated to advancing clinical research by leading operational aspects of trials, ensuring compliance with protocols and regulations, and fostering collaboration among stakeholders...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Lead transformative technology initiatives as a strategic Chief Technology Officer, driving modernization and AI integration while ensuring business continuity and team development in a dynamic softwa...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.