Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$134K - $249K *

Lead the charge in enhancing clinical systems operations, driving efficiency and effectiveness across pharmacy initiatives while managing a dedicated team and overseeing complex workflows and data int...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Take ownership of major fire protection projects, driving execution from planning to closeout. Collaborate with teams to ensure financial performance, quality standards, and safety while managing comp...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$106K - $159K *

Empower the commercial organization by developing and managing training programs, enhancing onboarding processes, and ensuring alignment across brands. Collaborate with leaders to drive continuous imp...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Take ownership of key client relationships, driving growth in the renewable energy analytics sector while collaborating across teams to support long-term strategic goals and ensure client success with...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$65K - $150K *

Unlock potential by collaborating with cross-functional teams to enhance AI systems. Troubleshoot complex issues, improve performance, and empower users through effective training and support in a dyn...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $205K *

Transform security landscapes by conducting advanced vulnerability assessments and penetration testing. Collaborate with diverse teams to identify, communicate, and remediate risks associated with eme...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $133K *

Join a team that's building and leading a high-performing Business Development group. Drive prospecting strategies, enhance team performance, and collaborate with Sales and Marketing to accelerate pip...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$94K - $143K *

Lead the charge in high voltage substation design, collaborating with engineers and designers to create detailed drawings and ensure compliance with standards while mentoring team members and managing...

3 days ago

  •   11 - 15 years exp.  •   Technical Services

$80K - $95K *

Lead a dynamic team of travel therapy recruiters while driving personal production. Champion recruitment strategies, enhance team performance, and ensure alignment with client demands to achieve booki...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Staffing

$80K - $95K *

Join a team that's dedicated to delivering precise radiation therapy treatments, collaborating with oncologists, and ensuring patient safety and comfort while utilizing advanced technology and techniq...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $150K *

Unlock potential by driving hardware security assessments, improving client security postures, and delivering actionable insights. Collaborate with teams and engage directly with clients while enhanci...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Advance configuration management practices to ensure integrity and compliance across all program artifacts. Collaborate with cross-functional teams to support audits, manage data deliverables, and mai...

Reposted 3 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$100K - $120K *

Optimize integration processes by bridging technical gaps between systems. Collaborate with campus IT to ensure seamless data flows, troubleshoot issues, and enhance integration reliability for succes...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$126K - $211K *

Elevate customer relationships by driving growth within oncology practices. Utilize a consultative approach to align solutions with client objectives and collaborate with internal teams to enhance bus...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $267K *

Champion innovation by leading cross-functional teams to design and deliver scalable, high-performance infrastructure solutions that enhance reliability and efficiency across diverse applications and...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

$92K - $139K *

Take ownership of onsite laboratory operations, driving service excellence and compliance while developing high-performing teams. Collaborate with clients and internal stakeholders to achieve exceptio...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$167K - $226K *

Explore the intersection of machine learning and robotics by developing cutting-edge computer vision systems that enhance robotic perception and sensing capabilities, directly impacting production har...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Optimize event sales and rentals by developing strategic income models, managing a dedicated team, and executing high-quality private events that enhance community engagement and support the theater's...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $220K *

Join a team that's redefining mobile robotics by leading the hardware development of an autonomous platform. You'll oversee electrical architecture, safety certification, and team mentorship, driving...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Champion patient access by providing education and support to patients, caregivers, and healthcare professionals. Collaborate across teams to enhance therapy access and ensure a seamless experience fo...

Waltham, MARemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Join a team that's building from the ground up, shaping the engineering foundation and culture while collaborating closely with leadership to define and deliver innovative products...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Engage with patients and healthcare teams to enhance access to therapies, ensuring a seamless support experience. Collaborate across functions to minimize barriers and drive compliance, while monitori...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $114K *

Elevate client well-being by providing tailored therapy services across various modalities. Collaborate with a dynamic team to create impactful treatment plans and foster personal growth in a flexible...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$500K+*

Join a team that's driving sales success through strategic leadership and collaboration. Oversee resource planning, manage budgets, and coach a team of Regional Sales Managers while achieving revenue...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$250K - $500K+*

Optimize and innovate software kernels for hardware integration, collaborating with ML Research and Hardware Engineering teams to enhance performance and efficiency in cutting-edge technology applicat...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.