Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.
Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.
Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.
Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.
Average Salary: $126,017
Systems Engineer, Decision Advantage
$147K - $196K *
Unlock potential by leading the design and validation of advanced systems, integrating complex hardware and software solutions. Collaborate across teams to ensure robust performance and meet customer...
2 days ago
Physician Assistant or Nurse Practitioner, Urgent Care - Nantucket
$130K - $173K *
Shape the future of patient care by managing diverse populations in an Urgent Care setting. Leverage your Family Medicine background to perform assessments, develop care plans, and provide high-qualit...
2 days ago
SVP, Marketing Growth & Partnerships
$230K *
Lead the charge in rebuilding and managing a national Market Growth team, driving student enrollment through strategic partnerships and innovative local engagement. Foster a collaborative environment...
2 days ago
Bluespine-Savings Realization Manager
$110K - $130K *
Lead the transformation of insights into actionable savings for clients. Collaborate with employers and vendors to optimize health benefits, drive execution, and enhance product offerings while shapin...
2 days ago
Radiologic Technologist (Rad Tech)
$65K - $104K *
Transform patient care as a Radiologic Technologist, combining your expertise with clinical support in a dynamic urgent care setting. Collaborate with a dedicated team to ensure accurate diagnoses and...
2 days ago
$145K - $222K *
Deliver impactful leadership by managing multi-discipline nuclear projects, ensuring alignment across teams, and guiding successful execution from design to closeout while maintaining client relations...
2 days ago
$131K - $190K *
Champion the design and optimization of scalable data pipelines and real-time ingestion frameworks, leading complex data initiatives while ensuring performance, reliability, and governance align with...
2 days ago
$102K - $172K *
Take ownership of complex outage management for gas and steam turbines, ensuring effective planning, execution, and closeout of events. Drive best practices and customer engagement while optimizing op...
2 days ago
Senior Machine Learning Engineer, Ads Forecasting & Scenarios
$216K - $303K *
Discover an exciting opportunity to drive innovation in ad optimization and marketplace quality, creating impactful bidding and auction systems that enhance user experience and maximize advertiser suc...
Reposted 2 days ago
$243K - $393K *
Lead clinical trial efforts for innovative gene editing therapies, ensuring scientific integrity and patient safety. Collaborate with cross-functional teams to drive development from Phase 1 to later...
2 days ago
$181K - $266K *
Lead the charge in overseeing regional operations across multiple sites, ensuring compliance and safety while fostering a collaborative culture. Drive strategic initiatives and integrate acquired faci...
2 days ago
Communications and Digital Director
$113K - $116K *
Shape the future of communications strategy by leading digital engagement and outreach efforts. Collaborate with leadership to amplify youth voices and support educators through impactful messaging an...
2 days ago
$144K - $216K *
The Senior Program Manager will be technically responsible for all aspects of Uprate projects at Nuclear Power Plants, focusing on Balance of Plant License Basis and physical modifications. This role...
Reposted 2 days ago
Principal WW Storage Specialist , WW Storage Specialists
$176K - $238K *
Innovate your career by shaping the GTM strategy for AI and HPC solutions. Collaborate with top-tier clients and cross-functional teams to drive adoption and growth of cutting-edge technologies on AWS...
2 days ago
Enterprise New Business Account Executive
$101K - $159K *
Elevate your career by driving strategic growth through high-value enterprise sales. Leverage your expertise in MEDDIC principles to secure opportunities, manage complex deals, and foster long-term cl...
2 days ago
$150K - $180K *
Elevate company performance by partnering with the CEO to drive strategic initiatives, enhance operational efficiency, and ensure alignment across teams. This role demands analytical prowess and excep...
2 days ago
New Business Account Executive, Mid Market
$62K - $105K *
Drive growth by engaging mid-sized organizations, navigating complex sales cycles, and crafting tailored solutions that address client challenges while managing stakeholder relationships to secure new...
2 days ago
Lifecycle Marketing Manager (Remote)
$88K - $105K *
Lead the charge in developing and executing multi-channel lifecycle strategies to enhance patient and provider engagement in mental healthcare. Collaborate across teams to optimize campaigns and drive...
2 days ago
Head of Global Events & Executive Programs
$246K - $310K *
Champion a global events strategy that elevates brand awareness and drives executive engagement. Collaborate across teams to optimize event ROI and lead large-scale programs, ensuring compliance and e...
2 days ago
Publications Manager- Immunology
$108K - $130K *
Lead the charge in executing strategic publication plans, overseeing cross-functional teams to deliver high-quality scientific publications that align with organizational objectives and enhance commun...
2 days ago
Senior Electrical Engineer - Safety & Systems Integration (On-site)
$150K - $195K *
Elevate your career by designing and validating cutting-edge electrical systems for an innovative mobile manipulation platform. Collaborate on safety and integration aspects, taking projects from conc...
2 days ago
PV Aggregate Reports Scientist
$122K - $163K *
Lead the charge in managing aggregate safety reports, ensuring compliance and quality. Collaborate with cross-functional teams to enhance processes and provide expert insights on pharmacovigilance req...
2 days ago
$117K - $153K *
Join a dynamic team as you manage attorney recruiting for practice groups, driving strategic growth through candidate management, stakeholder collaboration, and process optimization. Your expertise wi...
2 days ago
$160K - $200K *
Unlock potential by partnering with early-stage startups to build robust financial foundations. As a CFO-in-Residence, you'll drive critical finance functions, support fundraising, and shape strategic...
2 days ago
Senior Advisor for Human Services
$100K - $120K *
Join a team that's shaping the future of human services by providing strategic guidance and operational support. Collaborate with leadership to drive cross-agency initiatives, enhance service delivery...
2 days ago
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.
Where in Massachusetts can I find high-paying jobs?
Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.
How can I search for Massachusetts jobs paying $100,000 or more?
Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.
Are Massachusetts jobs on Ladders vetted?
Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.