Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$152K - $230K *

Shape the future of industrial systems by leading complex process engineering projects, translating fundamental requirements into practical designs, and guiding them from concept through operation wit...

2 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$109K - $160K *

Transform production processes by leading a dynamic team in high-precision manufacturing. Collaborate cross-functionally to enhance prototype builds and streamline operations, ensuring alignment with...

2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$93K - $105K *

Lead operational excellence and uphold integrity as a Lieutenant, overseeing departmental efficiency, emergency response, and compliance. Drive team performance while ensuring safety and fiscal respon...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$93K - $105K *

Advance your career by overseeing operational efficiency and discipline as a Lieutenant. Lead department personnel, manage critical incidents, and ensure compliance with standards while fostering a sa...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Elevate patient care by providing expert pharmacy consulting and clinical services. Collaborate with a dedicated team to ensure medication safety, educate patients, and mentor colleagues in a supporti...

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$168K - $310K *

Lead the charge in designing cutting-edge SRAM circuits for next-gen AI chips, optimizing performance and power while collaborating with cross-functional teams to deliver innovative memory solutions a...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $110K *

Help us optimize inventory levels and purchasing strategies to support business goals. Collaborate with cross-functional teams to ensure product availability and drive financial success through effect...

2 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$59K - $106K *

Transform tactical ISR operations by executing preflight, flight, and post-flight duties. Leverage advanced sensor technology to provide critical analysis and support for diverse missions, ensuring ef...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$149K - $172K *

Lead the charge in shaping and executing EHS strategies across the Americas, ensuring compliance and fostering a proactive safety culture while collaborating with cross-functional teams to enhance pro...

RemoteRemote

2 days ago

  •   11 - 15 years exp.  •   Healthcare

$211K - $272K *

Transform your career by leading enterprise applications strategy and delivery. Collaborate with cross-functional teams to enhance processes, drive AI adoption, and ensure robust application architect...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$129K - $165K *

Contribute to advancing oncology care by collaborating across teams to enhance evidence-based practices, improve patient outcomes, and ensure compliance with standards. Leverage your expertise to ment...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$129K - $165K *

Advance patient care by collaborating across disciplines to enhance oncology practices, ensuring compliance and quality. Leverage expertise to mentor nursing staff and implement evidence-based solutio...

Boston, MARemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$129K - $165K *

Contribute to patient care excellence as a Clinical Practice Specialist, collaborating across departments to enhance oncology practices, ensure compliance, and mentor nursing staff in evidence-based a...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by building strategic relationships with athletic associations, leading RFPs, and driving school subscriptions. Own the growth strategy in new states with autonomy to shape processes...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Lead the development of advanced model capabilities, enhancing automation and logistics through rigorous experimentation and evaluation. Collaborate across research, engineering, and operations to dri...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $175K *

Drive the development of a cutting-edge platform, leading full-stack engineering efforts to enhance user experience and data insights for pharma clients, while ensuring scalability and reliability in...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $200K *

Transform clinical research by leading operational oversight of studies, ensuring compliance with protocols and regulations. Collaborate with teams to drive site feasibility, manage budgets, and enhan...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$380K - $440K *

Drive strategic clinical development for innovative ophthalmology therapies, focusing on rare retinal diseases. Lead cross-functional teams to execute global strategies from early-stage trials to regu...

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Champion new business opportunities in the diagnostic sales sector, driving growth in non-acute care markets. Achieve sales quotas, foster client relationships, and implement innovative technologies t...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$220K - $300K *

Shape the future of financial strategy by leading comprehensive reporting, planning, and analysis. Collaborate with cross-functional teams to enhance decision-making and drive performance, while ensur...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Advance your career as an Environmental Permitting Specialist, leveraging your expertise in Massachusetts regulations to support energy and infrastructure projects. Collaborate with a leading team whi...

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$111K - $130K *

Join a team that's transforming healthcare delivery through innovative product management. You'll oversee the Lighthouse platform, enhancing care team efficiency while collaborating with cross-functio...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower your career by joining a dynamic team focused on environmental permitting and natural resource management. Collaborate on energy projects and infrastructure improvements while leveraging your...

Chelmsford, MARemote

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $110K *

Advance your career by leading tax engagements, providing expert consulting, compliance, and planning services while mentoring junior associates in a dynamic healthcare-focused environment...

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $110K *

Elevate your career by leading tax engagements, providing expert consulting, and ensuring compliance for diverse clients. Collaborate with a dynamic team to deliver exceptional service and mentor new...

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.