Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,012

Sort By: Relevance

$79K - $112K *

Advance knowledge in behavioral neuroscience by establishing a funded research program, mentoring students, and collaborating within a vibrant academic community. Engage in innovative research and con...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$105K - $191K *

Unlock your potential by leading advanced energy audits and driving impactful energy projects. Collaborate with cross-functional teams to enhance building efficiency and mentor the next generation of...

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $190K *

Lead the charge in managing U.S. Government contracts, guiding negotiations and compliance throughout the acquisition lifecycle. Collaborate with internal teams to ensure successful partnerships and m...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$79K - $118K *

Elevate customer experiences by providing expert training and support for diabetes management technology. Collaborate cross-functionally to enhance product usage and ensure customer satisfaction throu...

Massachusetts, USRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $330K *

Drive strategic leadership and operational excellence in U.S. Medical Affairs for Prescription Dermatology, ensuring compliance and high-quality evidence generation while collaborating with cross-func...

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by driving pipeline visibility and forecasting accuracy. Collaborate with Sales, Marketing, and Finance to enhance workflows and insights, ensuring clean data and effective GTM strate...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$149K - $202K *

Transform the HCP launch landscape by leading innovative marketing initiatives for a groundbreaking treatment in Sjögren's disease. Collaborate cross-functionally to engage healthcare professionals an...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$84K - $118K *

Accelerate progress at the forefront of population health by joining a dynamic fellowship designed for emerging leaders in value-based care, clinical innovation, and health equity. Engage in hands-on...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$133K - $160K *

Empower veterinary care by joining a supportive team dedicated to transforming pet health. Enjoy autonomy, mentorship, and a positive culture while utilizing advanced technology and resources to enhan...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$181K - $250K *

Transform financial strategy at the enterprise level by leading FP&A processes, delivering insights, and enhancing reporting capabilities to support informed decision-making for senior leadership and...

2 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $125K *

Join a team that's transforming HR and payroll solutions by engaging clients, conducting tailored demos, and bridging business needs with technical expertise to enhance workforce management and compli...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $189K *

Innovate in cybersecurity by developing predictive models and methodologies. Collaborate across teams to enhance risk assessment tools and translate complex analytics into scalable solutions, driving...

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$124K - $198K *

Transform your career by owning and accelerating Unstructured data protection sales. Leverage your technical expertise to drive growth, engage stakeholders, and win competitive deals in a dynamic, quo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Engage with field service teams to drive operational excellence, lead strategic initiatives, and enhance employee engagement across multiple sites. Create a culture of safety, accountability, and inno...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$95K - $115K *

Grow your career with a strategic leadership role overseeing field service teams, managing budgets and resources, and driving excellence through customer engagement and operational performance across...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$88K - $105K *

Drive exceptional service delivery by leading a motivated team dedicated to operational excellence, managing workforce planning, budgets, and ensuring optimal performance across multiple sites. Empowe...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$201K - $393K *

Lead the development and execution of global clinical trials for women's health compounds, collaborating with cross-functional teams to shape clinical strategies and ensure compliance with regulatory...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$192K - $253K *

Join us to lead the development of data and technology strategies that drive scientific and operational excellence. Oversee a multidisciplinary team and collaborate with stakeholders to deliver impact...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$86K - $138K *

Champion data-driven solutions by collaborating with cross-functional teams to analyze complex business needs, create operational reports, and enhance capabilities, ensuring quality delivery and compl...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower clinical excellence by delivering expert technical support for neurovascular products. Collaborate with healthcare professionals to enhance patient care, drive product adoption, and ensure suc...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$275K - $325K *

Drive the growth of healthcare practices by owning strategy, partnerships, and P&L. Collaborate with teams to deliver tailored financial solutions, while leveraging your network to establish Flex as t...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $90K *

Elevate your career by building and maintaining a network of specialist consultants and physicians. Drive business growth and enhance clinical trial delivery through strong relationships and strategic...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Unlock potential by driving new business growth in the sports industry, leveraging your extensive network and sales expertise to close strategic deals and innovate through AI solutions for sports orga...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$69K - $101K *

Manage supplier relationships and procurement processes to ensure seamless production. Collaborate with cross-functional teams to track costs, monitor delivery performance, and resolve material shorta...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.