Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,888

Sort By: Relevance

$105K - $123K *

Unlock potential by supporting compliance risk management frameworks and processes. Engage with teams to enhance governance, reporting, and performance metrics, ensuring effective compliance and contr...

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $180K *

Elevate our platform's infrastructure by designing, deploying, and maintaining robust cloud solutions. Ensure reliability and security while optimizing performance and costs, enabling our clients to t...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$254K - $305K *

Engage with us to design and evaluate vision models for in-cabin perception, enhancing rider safety and experience. Own model areas end-to-end, collaborating across teams to ensure reliable operations...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$190K - $316K *

Lead a high-performing platform engineering organization to deliver secure, reliable infrastructure services globally. Drive strategy, execution, and operational management across cloud, AI, and core...

RemoteRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Collaborate with clients to design, build, and integrate Power BI solutions, enhancing dashboard UI/UX and driving data insights through effective team engagement and innovative data modeling techniqu...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$112K - $189K *

Join us to ensure safe, effective medication therapy while advancing pharmaceutical care. Collaborate with healthcare teams, educate future practitioners, and support drug-related research to optimize...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a dynamic team to drive the development of a cutting-edge marketplace, enhancing provider products and economic incentives while collaborating closely with engineering and operations to transform...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Lead the design and governance of clinical ontologies and terminology services, ensuring data quality and alignment with product needs. Collaborate cross-functionally to enhance data normalization and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$192K - $288K *

Join a team that's driving strategic initiatives in Neuroscience and Oncology. In this pivotal role, you'll partner with leadership to enhance operations, manage budgets, and streamline workforce plan...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$118K - $134K *

Unlock potential by driving innovative software solutions in a collaborative, fast-paced environment. Contribute to modernizing business applications while working closely with IT and business teams t...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $145K *

Unlock potential by bridging business needs with technical solutions. Collaborate with stakeholders to define requirements, manage product backlogs, and ensure successful delivery of ServiceNow capabi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$78K - $122K *

Support executive leadership by managing complex schedules, communications, and operations. Foster organizational culture through strategic insights and proactive problem-solving, ensuring efficient w...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$230K - $345K *

Shape the future of late-stage oncology clinical trials by leading strategic initiatives, ensuring operational excellence, and fostering cross-functional partnerships to drive successful trial executi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform the renewable energy landscape by managing data portfolios, analyzing project performance, and enhancing financial reporting. Collaborate with cross-functional teams to drive strategic energ...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$201K - $309K *

Elevate security standards by leading the development of innovative software solutions. Collaborate with cross-functional teams to integrate robust security measures, ensuring the integrity of applica...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Lead the charge in optimizing ERP systems for Finance, overseeing strategic projects and ensuring seamless integration. Collaborate with stakeholders to enhance application performance and deliver inn...

Yesterday

  •   11 - 15 years exp.  •   Energy & Utilities

$110K - $130K *

Lead your career with impactful financial management, overseeing capital planning and budgeting initiatives. Drive agency-wide strategies, optimize resources, and provide senior-level analysis to enha...

Yesterday

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Join us to drive strategic relationships with enterprise customers, optimizing IGEL technology solutions. This hands-on role balances technical expertise with customer management, focusing on the Fina...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$160K - $200K *

Elevate the People function as a strategic partner, driving talent strategy, organizational design, and culture in a dynamic, global environment. Shape leadership effectiveness and enhance employee ex...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $130K *

Drive the development of Foreign Military Sales (FMS) cases by providing expert guidance and strategic support. Collaborate with stakeholders to ensure compliance and optimize processes, enhancing int...

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$115K - $151K *

Join us in shaping scalable digital experiences across web and mobile. Leverage your expertise in full stack development, cloud technologies, and emerging practices to deliver high-quality solutions i...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$115K - $151K *

Lead the charge in developing scalable web and mobile applications using cutting-edge technologies. Collaborate with cross-functional teams to deliver high-quality solutions while adopting modern engi...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$94K - $157K *

Unlock potential by joining our team as a Data Analyst, where you'll leverage your expertise in data manipulation and visualization to support key Federal clients, driving impactful solutions through...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$174K - $261K *

Drive enterprise identity governance by leading a specialized sales team, engaging with senior executives, and orchestrating complex sales cycles to modernize access management and reduce compliance r...

Yesterday

  •   Less than 5 years exp.  •   Consumer Technology

$107K - $204K *

Transform enterprise software deployment by leveraging DevSecOps principles and cloud technologies. Collaborate with engineering teams to modernize legacy systems and enhance application lifecycle man...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.