Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,893

Sort By: Relevance

$193K - $309K *

Innovate AI-driven automations for customer care, enhancing workflows and agent efficiency. Collaborate across teams to transform service operations, leveraging intelligent systems for improved custom...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Shape the future of Surety pricing by owning and enhancing the SDI pricing model. Collaborate with underwriting leadership, conduct complex analyses, and mentor peers to drive strategic business decis...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$175K - $220K *

Join a team that's shaping infrastructure projects through expert scheduling leadership. Your strategic planning and risk management skills will optimize resource use and ensure timely delivery in a c...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Real Estate & Construction

$126K - $215K *

Lead the development of complex regulatory clinical documents, ensuring quality, compliance, and timely delivery. Mentor fellow writers and collaborate with cross-functional teams to advance patient h...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Explore the dynamic field of in-building RF design and deployment, optimizing DAS systems for mobile operators. Collaborate with project teams to enhance designs, manage installations, and ensure comp...

Today

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$90K - $110K *

Accelerate talent acquisition by partnering with leaders to build candidate pipelines, drive recruiting efforts, and ensure timely hiring across corporate functions in a dynamic, project-driven enviro...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$145K - $160K *

Reimagine fundraising leadership by driving multi-state strategies and engaging high-value donors. Lead a dynamic team to achieve ambitious revenue goals while fostering collaboration and accountabili...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Transform enterprise software development by leveraging AI to create autonomous agents and workflows. Drive modernization of legacy systems with innovative solutions, focusing on automation and archit...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Transform intelligence analysis by leveraging your expertise and analytical skills. Collaborate with a dynamic team to support critical missions, utilizing advanced technology and methodologies to dri...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Transportation

$101K - $137K *

Contribute to transactional finance activities across the procure-to-pay lifecycle, ensuring accurate processing of financial transactions while supporting operational workflows and maintaining data i...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Champion the integration of clinical services by leading a diverse psychology team, ensuring high-quality care through supervision, training, and compliance with standards while providing direct patie...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$95K - $115K *

Drive impactful behavioral health initiatives by leading statewide programs focused on promotion, prevention, and wellness. Collaborate with diverse stakeholders to enhance community capacity and achi...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$141K - $204K *

Drive strategic growth for DSD by leveraging data, analytics, and tools to enhance operational performance and achieve expansion goals. Collaborate with leadership to support initiatives that elevate...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Empower our sales team by driving dealer management and business growth across the Southeast. Leverage your technical expertise and relationship skills to enhance market share and support distributor...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$102K - $152K *

Transform executive support by leading a dynamic team of EAs, enhancing processes, and driving strategic initiatives that align with company goals while fostering a collaborative culture...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$136K - $214K *

Lead the charge in optimizing revenue operations by managing a dynamic team, enhancing forecasting processes, and ensuring data integrity across systems. Collaborate closely with sales leadership to d...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Help us drive excellence in clinical training across our regional centers. You'll oversee training programs, evaluate clinical care quality, and collaborate with leaders to ensure compliance with best...

Today

  •   5 - 7 years exp.  •   Healthcare

$133K - $209K *

Lead the charge in optimizing deal structures and contract management, collaborating with cross-functional teams to streamline workflows and enhance the sales process. Your analytical skills will driv...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$94K - $142K *

Champion enterprise growth by identifying and advancing strategic opportunities across healthcare networks. Build relationships with key stakeholders to develop impactful business cases and partnershi...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in managing our growth roadmap, ensuring seamless integration across marketing, data, and engineering teams while maintaining data integrity and optimizing performance metrics for succ...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $110K *

Elevate your career by driving innovative structural designs for light-gauge and cold-formed steel systems in modular and prefabricated buildings, ensuring compliance with California codes and enhanci...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$170K *

Lead the charge in engineering excellence by managing API, Web, and Mobile teams, ensuring seamless execution and alignment with product goals while driving technical ownership and fostering team grow...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in innovative immunology research, developing novel methods for pathogenic cell depletion. Collaborate across teams to drive discovery and optimize therapeutic strategies, contributing...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $150K *

Join a compassionate team dedicated to providing gentle end-of-life care for pets in their homes. Enjoy a flexible schedule, meaningful interactions, and the opportunity to make a lasting impact on fa...

Today

  •   Less than 5 years exp.  •   Healthcare

$85K - $105K *

Join a team that's dedicated to enhancing the quality of care in our Home Health and Private Duty department. Oversee operations, support caregivers, and ensure compliance while fostering teamwork and...

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.