Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,130

Sort By: Relevance

$174K - $209K *

Empower our team by driving innovative projects from concept to operation, enhancing the reliability and performance of our observability systems while collaborating in a fully remote environment focu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $145K *

Transform the future of spatial surgery by driving market growth, engaging with stakeholders, and executing comprehensive sales strategies across regions to enhance surgical planning and performance...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $145K *

Lead the charge in advancing sports medicine through strategic engagement and market development of innovative surgical technologies, while ensuring exceptional training and support to enhance clinica...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $145K *

Unlock the potential of spatial surgery by driving commercialization and customer engagement through relationship building and strategic market development in a fast-paced sales environment across mul...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $145K *

Drive market growth by leading the commercialization of a pioneering surgical platform, focusing on customer engagement, sales pipeline management, and training to enhance surgical capabilities in you...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's committed to environmental excellence, leading compliance for airport projects. Oversee assessments, manage permits, and ensure adherence to regulations while integrating sustainabi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$80K - $95K *

Shape the future of infrastructure by designing and overseeing innovative structures. Collaborate with architects and engineers to ensure compliance and integrity while mentoring junior team members i...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$175K - $225K *

Transform data engineering practices by architecting scalable platforms, driving reliability, and mentoring teams. Lead cross-functional initiatives to enhance data governance and leverage AI tools fo...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$105K - $125K *

Lead technology operations for global teams, optimizing systems and support. Collaborate on strategic AI solutions, ensuring compliance and enhancing workflows. Drive efficiency and innovation in a dy...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$210K - $250K *

Drive growth and innovation in clinical development, leading cross-functional teams to enhance therapeutic portfolios, particularly in cell and gene therapy, while ensuring medical oversight and strat...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Drive the growth of a therapeutic portfolio by leveraging medical expertise and overseeing clinical trials. Collaborate across teams to shape strategies in cell and gene therapy, ensuring innovative...

Covington, KYRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $120K *

Transform store operations by developing leadership skills across merchandising, financial management, and customer experience. Prepare for a Store Manager role through hands-on training and community...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$125K - $150K *

Drive your career with a pivotal role in Medical Informatics sales, focusing on building relationships, achieving revenue goals, and collaborating across teams to enhance customer experiences and expa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K *

Take ownership of cybersecurity compliance initiatives, leading risk management and strategic advisory services to enhance client security programs and ensure adherence to regulatory standards across...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Accelerate client success by leading complex HubSpot implementations, translating business needs into scalable solutions, and optimizing revenue operations. Build strong relationships with clients whi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Innovate compelling visual concepts that elevate brand storytelling across digital and print. Collaborate with teams to create high-quality designs, ensuring cohesive campaigns that engage audiences a...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$80K - $90K *

Drive financial accuracy and reporting for a diverse portfolio, utilizing advanced accounting skills to prepare and deliver comprehensive financial statements while ensuring compliance with establishe...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead pre-sales engineering efforts, crafting innovative networking and security solutions. Collaborate with teams to address customer needs, drive revenue, and mentor peers while staying current with...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Lead a dynamic digital service desk, enhancing web operations and stakeholder engagement while managing workflows, content publishing, and operational improvements across HHS digital platforms...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $187K *

Manage client relationships and oversee business development efforts, driving sales strategy and ensuring delivery assurance by aligning client expectations with service offerings while monitoring per...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Drive the implementation and optimization of Oracle Cloud Financials solutions, collaborating with clients to translate complex finance requirements into effective strategies. Lead functional workstre...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$100K - $120K *

Manage the end-to-end SIT testing strategy, leading QA teams and ensuring quality across projects. Collaborate with stakeholders to develop test plans, oversee execution, and drive continuous improvem...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Staffing

$180K - $215K *

Tackle the challenge of launching a groundbreaking product by leading a high-performing sales team, driving regional execution, and fostering key customer relationships in a dynamic, fast-paced enviro...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Lead the charge in driving regional sales success through strategic execution, team leadership, and cross-functional collaboration. Foster strong customer relationships and ensure alignment with corpo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$98K - $163K *

Drive your career forward by transforming financial management processes, enhancing operational efficiency, and collaborating with senior stakeholders to implement innovative solutions in a dynamic co...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.