Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$100K - $120K *

Unlock potential by providing personalized primary care to seniors in their homes. Collaborate with interdisciplinary teams to enhance patient outcomes while managing chronic conditions and acute visi...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$91K - $163K *

Transform clinical documentation practices by leading a team focused on improving accuracy and completeness in inpatient records. Collaborate with healthcare professionals to enhance documentation qua...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Accelerate growth in Biologics by leading global business development efforts, driving new market creation, and forging strategic partnerships. Collaborate across teams to implement data-driven strate...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Innovate data solutions by developing complex reports and analyses to support senior management and client needs. Collaborate with teams to enhance data literacy and provide technical guidance across...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Lead the charge in developing scalable audience solutions by integrating predictive models and data workflows. Collaborate with cross-functional teams to enhance audience activation and ensure reliabl...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Technical Services

$88K - $92K *

Transform military healthcare by delivering patient-centered case management services, ensuring coordinated, evidence-based care for Army Special Operations Forces and their families, while enhancing...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $85K *

Elevate your career by analyzing complex litigation claims, ensuring timely resolutions, and delivering exceptional client service in a dynamic, supportive environment. Join a global leader committed...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Transform your career by managing custom automation projects from design to delivery. Lead cross-functional teams, ensure customer satisfaction, and drive financial results while navigating complex pr...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$84K - $131K *

Unlock your potential as a key player in implementing SAP Manufacturing solutions. Collaborate with clients to optimize operations, enhance efficiency, and drive innovation in a dynamic consulting env...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $140K *

Lead transformative healthcare initiatives by fostering client relationships, driving impactful research, and developing high-performance teams to achieve strategic goals and business growth...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $200K *

Shape the future of wealth management by leading investment strategies for High Net Worth clients. Drive AUM growth, manage portfolios, and deliver tailored investment solutions while collaborating wi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $120K *

Engage in leading field operations for commercial construction projects nationwide. Oversee safety, subcontractor coordination, and project execution from start to finish, ensuring timely delivery and...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $120K *

Transform your career by leading field operations on diverse commercial construction projects nationwide. Oversee safety, scheduling, and subcontractor coordination from groundbreaking to closeout, en...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Transform geospatial data into impactful maps and applications, supporting intelligence operations. Collaborate with teams to analyze and visualize data, ensuring compliance with standards while enhan...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$120K - $145K *

Champion the modernization of enterprise data tiers by automating database reliability engineering across hybrid cloud environments, enhancing performance, and ensuring high availability for mission-c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Elevate your career by driving growth through strategic business development in the industrial sector. Collaborate with enterprise clients, build relationships, and close deals while leveraging innova...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$175K - $210K *

Lead a dynamic team to drive presales and solution architecture for enterprise transformation, shaping innovative technology solutions and enhancing client engagements while fostering a high-performin...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Lead the charge in enterprise sales by hunting new logos within the Life Sciences sector. Build relationships with Salesforce partners to enhance co-selling opportunities while managing your own pipel...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Drive the design and management of cloud infrastructure, ensuring secure, scalable systems that align IT operations with business goals. Lead initiatives in automation and DevSecOps to enhance operati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$96K - $101K *

Empower domestic workers by leading impactful research initiatives that inform advocacy and policy development. Drive strategic research agendas, mentor a dedicated team, and collaborate with diverse...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $96K *

Optimize medical imaging operations by troubleshooting, repairing, and maintaining equipment. Collaborate with service management to ensure high-quality patient care through effective installations an...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$92K - $135K *

Grow your career with a dynamic role providing actuarial support for commercial lines, managing projects, analyzing market trends, and ensuring compliance while advancing your actuarial expertise thro...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Manage delivery leadership for life sciences CRM transformation programs, ensuring high-quality implementations and migrations. Collaborate with cross-functional teams to meet client expectations and...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Elevate project success by managing the lifecycle of commercial sales initiatives. Collaborate across teams to ensure accurate documentation, financial oversight, and timely invoicing, driving efficie...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Elevate your career with a pivotal role overseeing accounting operations, leading a team, and ensuring accurate financial reporting. Drive continuous improvement while collaborating across departments...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.