Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$71K - $125K *

Transform complex loan servicing processes as a Senior Servicing Officer, managing a diverse portfolio in commercial real estate. Contribute to client partnerships and lead initiatives, while expandin...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $150K *

Unlock secure customer experiences by designing and implementing identity solutions. Collaborate with cross-functional teams to enhance authentication processes, ensuring seamless onboarding and login...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $245K *

Empower your career by leading regulatory advertising initiatives, ensuring compliance while collaborating with cross-functional teams to develop impactful product messaging for marketed and pipeline...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$128K - $210K *

Manage regulatory activities for advertising and promotion, ensuring compliance while collaborating with cross-functional teams to develop impactful product messaging and materials that align with com...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $190K *

Unlock potential by designing scalable data models and ensuring data quality. Collaborate with cross-functional teams to translate business needs into technical solutions, driving analytics excellence...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$75K - $95K *

Shape the future of clinical research data integrity by leading a dedicated team. Drive operational excellence, ensure compliance, and foster cross-functional partnerships to enhance data quality and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$136K - $200K *

Champion employee advocacy by leading initiatives that enhance workplace relationships, drive positive employee experiences, and ensure effective communication across teams, while leveraging data anal...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$90K - $120K *

Champion customer success by driving engagement and building lasting relationships with enterprise clients. Collaborate across teams to ensure exceptional user experiences and achieve measurable outco...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Lead a dynamic content development team to create high-quality curriculum materials for K-8 science education. Oversee project management, ensure content consistency, and drive team performance to mee...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$178K - $366K *

Shape the future of privacy compliance by providing strategic counsel to cross-functional teams, ensuring products meet EU regulations while balancing business goals. Drive scalable processes and lead...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Engineer innovative data-driven web applications, bridging data engineering and analytics. Own end-to-end features, transforming complex data into user-friendly tools that enhance customer experience...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive patient access to Provenge by removing reimbursement barriers and collaborating with healthcare stakeholders. Develop strategies to enhance business growth while navigating complex payer policie...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Drive exceptional healthcare delivery while fostering patient relationships and community engagement. Ensure quality care, maintain clinic operations, and support team collaboration to enhance patient...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$80K - $95K *

Elevate clinical standards by leading ABA programs, mentoring BCBAs, and collaborating with interdisciplinary teams to enhance patient outcomes and ensure ethical practices in a supportive environment...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Drive operational excellence by leading a global team to enhance post-sale services, optimize processes, and ensure customer satisfaction. Collaborate across departments to implement scalable solution...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$81K - $90K *

Manage the leave of absence program, ensuring compliance and support for associates. Collaborate with stakeholders to enhance leave experiences and ADA accommodations while maintaining accurate record...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Drive the planning and execution of complex therapeutic programs from discovery to clinic. Serve as a senior program management partner, ensuring successful execution and alignment across cross-functi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Shape the future of LPG tank sales by driving revenue growth and building lasting relationships across the Western US. Lead customer engagement, execute strategic initiatives, and ensure consistent pe...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Lead the charge in delivering exceptional pharmaceutical care, ensuring patient safety and satisfaction while managing pharmacy operations and training associates to uphold high standards of service a...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$120K - $160K *

Transform data into actionable insights by owning the analytics pipeline from ingestion to visualization. Collaborate with cross-functional teams to create trusted models and metrics that empower deci...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$88K - $105K *

Join a team that's dedicated to environmental remediation, focusing on system design, operations, and investigations. Collaborate with engineers and scientists to deliver innovative solutions while en...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $135K *

Champion global retail operations by optimizing fulfillment processes, enhancing customer satisfaction, and managing relationships with 3PLs and retailers. Collaborate with sales teams to ensure timel...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$140K - $155K *

Empower teams to elevate product design through strategic vision, fostering collaboration across disciplines to create impactful digital experiences that meet user needs and business goals while ensur...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$123K - $158K *

Unlock your potential by driving enterprise sales growth across the Americas. Collaborate with cross-functional teams to manage the full sales cycle, from prospecting to closing, while building strong...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$142K - $215K *

Elevate your career by driving new business growth in a dynamic sales environment. Own the full sales cycle, collaborate with teams, and exceed revenue goals while engaging with key stakeholders in a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.