Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$110K - $130K *

Champion patient care by leading pharmacy operations, mentoring technicians, and ensuring compliance with regulations. Drive growth and enhance service quality while fostering positive relationships w...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Accelerate product launches by coordinating cross-functional teams, managing timelines, and ensuring compliance with quality standards. Drive the stage-gate process and maintain a unified project mana...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$67K - $111K *

Shape the future of healthcare by delivering integrated behavioral health assessments and counseling as part of a multidisciplinary team, ensuring quality care coordination and support for patients in...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Join a dynamic team to drive product strategy and execution for public safety software. Collaborate across functions to deliver mission-critical solutions that enhance community safety and support eme...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $200K *

Shape the future of data center networking as a Principal Technologist, leading complex pre-sales engagement and architecture for AI infrastructure. Collaborate with top industry players to innovate s...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$148K - $263K *

Manage and maintain Oracle databases, leveraging expertise in Unix scripting and PL/SQL. Engage in data migration, interface development, and automated task management while collaborating within a dyn...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $113K *

Unlock operational excellence by leading continuous improvement projects, utilizing lean methodologies to enhance quality, reduce costs, and drive performance across manufacturing and administrative a...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Champion technical solution design and deployment readiness, translating customer needs into secure, scalable architectures. Collaborate with engineering and cybersecurity teams to ensure successful t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$229K - $260K *

Drive the technical direction for building and delivering containerized applications, ensuring reliability and security across deployments. Collaborate with teams to enhance automation and mentor engi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$140K *

Drive regional sales success by leading a dynamic team, achieving revenue goals, and fostering collaboration. Utilize your expertise in capital medical equipment sales to mentor Territory Managers and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Unlock your potential by leading quality initiatives and training programs to enhance team performance and compliance. Collaborate with management to drive operational excellence and support colleague...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$229K - $260K *

Lead the charge in designing and implementing a robust OTA update system, ensuring seamless deployment across diverse environments while mentoring engineers and driving technical excellence in distrib...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $118K *

Engage in driving revenue growth by expanding strategic partnerships and acquiring new enterprise clients. Merge expansion selling with net-new enterprise acquisition to establish a repeatable sales m...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$180K - $225K *

Join a team that's redefining semiconductor IP licensing. Drive complex sales cycles, engage with key stakeholders, and build long-term relationships that generate significant revenue in a fast-paced...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $158K *

Champion operational excellence by leading facilities management across a multi-state portfolio. Drive strategic initiatives, optimize vendor performance, and implement scalable processes to support o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Engage in strategic partnership management to drive growth and innovation, overseeing development, negotiation, and execution of pivotal alliances. Collaborate cross-functionally to ensure alignment...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $135K *

Lead the strategic planning and execution of complex programs across multiple teams, ensuring alignment with business priorities and effective risk management. Drive delivery improvements and maintain...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Drive impactful pharmacy consulting services, educating patients on medication use and safety while delivering clinical healthcare solutions. Collaborate with a dedicated team to enhance patient care...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Join a team that's dedicated to providing expert pharmacy services and patient care. Collaborate with healthcare professionals to ensure medication safety, educate patients, and mentor pharmacy staff...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Provide expert pharmacy consulting and clinical healthcare services, ensuring medication safety and compliance. Mentor team members while delivering compassionate care and navigating patient challenge...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Analyze revenue performance and drive strategic planning to connect company goals with actionable insights. Collaborate with leadership to enhance forecasting models and optimize GTM strategies, ensur...

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$125K - $150K *

Transform revenue operations by owning the bottoms-up revenue model, partnering with leadership to drive strategic planning and analysis, and ensuring alignment with growth targets in a dynamic, high...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$100K - $120K *

Empower our pharmacy team to deliver exceptional patient care, ensuring accurate prescription fulfillment and promoting health education while driving sales and maintaining compliance with regulations...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Unlock potential by providing exceptional pharmaceutical care, educating customers on health and wellness, and ensuring compliance with regulations while leading a team to maximize sales and customer...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$160K - $192K *

Join us to drive commercial performance by engaging healthcare providers, building relationships, and supporting product launches. Collaborate with cross-functional teams to ensure patient access to i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.