Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$177K - $221K *

Manage the strategy and execution of access marketing for oncology products, focusing on value propositions for payers and healthcare providers. Collaborate with cross-functional teams to ensure effec...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Champion product quality and regulatory compliance in fluorochemical manufacturing. Lead nonconformance investigations, enhance quality systems, and collaborate cross-functionally to ensure operationa...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Shape the future of engineering excellence by leading plant site functions, managing capital projects, and driving continuous improvement initiatives to enhance efficiency, safety, and quality. Foster...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$211K - $235K *

Drive patient access initiatives by leveraging oncology expertise to navigate reimbursement landscapes, educate stakeholders, and resolve complex access issues, ensuring timely therapy access for pati...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Contribute to strategic sales planning by translating brand objectives into actionable channel-specific strategies. Collaborate cross-functionally to drive product launches and ensure alignment betwee...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$82K - $150K *

Elevate your career by driving growth in the dental implant market. This role focuses on acquiring new customers, expanding market share, and positioning value-driven solutions, requiring a proactive...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$163K - $186K *

Optimize supplier relationships and oversee manufacturing activities to ensure high performance and compliance in pharmaceutical production. Lead cross-functional teams to achieve business objectives...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$204K - $246K *

Join a team that's dedicated to fostering a culture of ethics and compliance in the Neurology sector. Collaborate with cross-functional partners to integrate compliance into business strategies and en...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $120K *

Drive sales success by building relationships with dental professionals, promoting innovative products, and achieving targets. Leverage your expertise to deliver exceptional customer service and suppo...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Analyze talent strategies and enhance leadership capabilities across the Americas. Collaborate with HR and business leaders to implement talent management processes while managing initiatives that dri...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Champion project delivery by overseeing HV cable testing projects across North America. Ensure alignment with client expectations while managing resources, schedules, and budgets for successful comple...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$82K - $118K *

Champion effective project delivery by leading the commissioning, qualification, and verification processes for successful vertical startups while collaborating with cross-functional teams on budget a...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$157K - $224K *

Champion the evolution of developer tooling and CI/CD pipelines, leading a global team to enhance operational efficiency and drive platform modernization for a multi-tenant SaaS environment, ensuring...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $125K *

Join a dynamic team to oversee and enhance transportation and logistics operations. Lead strategies to improve efficiency, coordinate with internal and external partners, and drive continuous improvem...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Transportation

$120K - $140K *

Shape the future of industrial water solutions by driving sales growth, managing key accounts, and fostering enduring partnerships with customers and teams to enhance sustainable business outcomes and...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead supplier quality initiatives to ensure product conformity and drive continuous improvement. Collaborate with cross-functional teams to establish quality standards, manage audits, and enhance supp...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$115K - $160K *

Join a team that's dedicated to enhancing global security through advanced incident response and forensic analysis. Collaborate with top professionals to protect organizations from sophisticated threa...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $90K *

Transform financial insights into strategic initiatives, supporting planning and analysis as the organization scales. Collaborate across teams to enhance budget management, reporting, and performance...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Transform the request-to-quote experience for key customers by redesigning workflows, integrating AI agents, and optimizing processes to enhance speed and accuracy in quoting. Drive innovation and col...

5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$102K - $141K *

Join a team that's dedicated to enhancing sales performance through strategic process development, technology alignment, and targeted training. Collaborate with cross-functional teams to drive effecti...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Engage in comprehensive assessments of building performance and energy efficiency. Collaborate with clients to enhance sustainability practices while reducing operational costs through detailed audits...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$85K - $102K *

Elevate your career by reviewing and editing environmental and property assessments. Collaborate with field staff to ensure report accuracy and quality, while providing technical guidance and maintain...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $120K *

Take ownership of electrical project coordination on utility-scale solar sites. Ensure high-quality installations, manage contractor relationships, and maintain safety and efficiency standards while t...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$140K - $200K *

Optimize project outcomes by leading comprehensive electrical design reviews in renewable energy sectors. Ensure compliance with industry standards while effectively managing timelines and costs for d...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $140K *

Advance your career by driving full-cycle recruitment for diverse Sales and Go-To-Market roles. Collaborate with leadership to attract top talent, enhance candidate experience, and optimize hiring pro...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.