Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$151K - $237K *

Transform healthcare outcomes by engaging with KOLs and HCPs, analyzing scientific data, and fostering expert networks. Drive medical strategy and enhance patient care through compliant, insightful co...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $100K *

Join our dynamic team to drive growth as a Life Insurance Agent. Embrace a rewarding career with unlimited income potential, comprehensive training, and a supportive environment focused on your succes...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Join us in leading on-site project delivery, ensuring successful execution and coordination of construction activities across multiple locations. Drive performance, manage teams, and uphold safety sta...

4 days ago

  •   8 - 10 years exp.  •   Technical Services

$132K - $251K *

Join a team that's driving innovation in military airborne communication systems. Leverage your expertise to capture new business opportunities while collaborating with cross-functional teams and enga...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $95K *

Lead the charge in overseeing a national Audit & Compliance team, ensuring regulatory adherence, risk management, and operational excellence while driving process improvements and fostering cross-func...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Create and execute comprehensive food safety and compliance strategies across all facilities, ensuring best-in-class standards and regulatory adherence, while driving operational excellence and foster...

Reposted 4 days ago

  •   11 - 15 years exp.  •   Food & Beverages

$90K - $100K *

Join a team that's redefining the Fine & Decorative Arts landscape. Drive strategic growth by transforming buyer demand into actionable supply opportunities, enhancing seller partnerships, and optimiz...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $110K *

Lead the charge in managing a diverse portfolio of network organizations, fostering relationships, and implementing strategic capacity-building initiatives to enhance organizational performance and su...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Champion the delivery of civil works and architectural projects, overseeing contractors and ensuring high-quality execution from site prep to completion. Leverage your expertise to manage complex site...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$127K - $159K *

Transform corporate communications by crafting compelling content that enhances reputation, engages employees, and supports strategic initiatives. Collaborate across teams to manage projects and ampli...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $128K *

Analyze and monitor security alerts, investigate threats, and enhance SOC processes. Collaborate with teams to ensure cybersecurity measures are effective, while documenting incidents and providing te...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$75K - $142K *

Lead a team of specialists in managing absence and claim cases, ensuring operational excellence and high-quality service delivery while fostering a supportive and growth-oriented environment for team...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Unlock potential by leading our marketplace operations, connecting first responders with experienced coaches. Drive efficiency, manage cross-functional teams, and ensure seamless service delivery whil...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$123K - $157K *

Advance your career by leading strategic sourcing for metals, driving cost savings and supplier performance. Engage with cross-functional teams to influence decisions and ensure supply continuity whil...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$123K - $157K *

Lead the charge in global sourcing strategies for plastics, driving supplier relationships and cost optimization while ensuring supply continuity and supporting new product introductions across manufa...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$184K - $254K *

Shape the future of Procurement by leading enterprise capabilities that enhance performance, streamline processes, and drive technology integration, ensuring measurable value and strategic alignment a...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$184K - $254K *

Shape the future of corporate strategy by leading cross-functional teams to develop enterprise-wide strategic plans, drive growth initiatives, and influence senior leadership decisions through data-dr...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$172K - $236K *

Drive architectural leadership for healthcare initiatives, shaping solutions and aligning teams with cloud strategies. Collaborate across functions to enhance interoperability and deliver impactful te...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Healthcare

$117K - $161K *

Empower innovation by leading full stack development and modernization efforts. Drive technical direction, mentor engineers, and enhance platform reliability across diverse systems in a collaborative...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Join a team that's driving innovation in project management for enterprise decisioning. Collaborate across business and technology teams to ensure successful delivery of complex initiatives while main...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $173K *

Transform member experiences by leading a dynamic marketing pod, driving execution and collaboration across teams to deliver personalized journeys efficiently and effectively, while maximizing platfor...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Champion the alignment of business requirements with implementation teams, ensuring documentation is clear and actionable. Drive the evolution of NBA standards and practices while managing configurati...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$138K - $191K *

Join a team that's redefining healthcare innovation by translating ideas into impactful solutions. Collaborate with senior executives to drive strategic initiatives and enhance population health throu...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$129K - $177K *

Drive the future of AI integration by designing and delivering agentic workflows that enhance user experiences. Lead a team while actively contributing to production code, ensuring reliable AI systems...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Shape the future of enterprise data capabilities by leading product strategy and agile teams to enhance personalized decision-making across channels. Collaborate with stakeholders to translate busines...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.