Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.
Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.
Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.
Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.
Average Salary: $108,152
$100K - $120K *
Engage with small and medium-sized businesses as a Direct Sales Leader, leveraging your extensive sales experience to train and mentor new team members while managing your own client relationships and...
Reposted 4 days ago
$80K - $95K *
Empower the CDL program by leading training initiatives, ensuring compliance, and optimizing fleet management. Collaborate with regional leaders to enhance operational efficiency and drive revenue gro...
4 days ago
$124K - $158K *
Lead pharmacy operations by ensuring safe dispensing, patient care, and team performance. Collaborate with management to enhance patient experiences and maintain compliance while fostering a supportiv...
4 days ago
CMC Program Lead TLX597 & TLX66
$135K - $160K *
Lead the charge in developing and executing CMC strategies for antibody-based radiopharmaceuticals, ensuring alignment with Stage-Gate requirements while managing cross-functional teams and external p...
4 days ago
Training Manager, Field Access & Reimbursement
$124K - $135K *
Shape impactful training programs for Field Access teams, enhancing access and reimbursement capabilities across therapeutic areas. Collaborate with stakeholders to ensure compliance and relevance, fo...
4 days ago
Staff Pharmacist - Accredo - Remote (AZ, FL, IN, OH, PA)
$112K - $189K *
Lead the charge in delivering exceptional pharmaceutical care by interpreting prescriptions, consulting with patients, and ensuring quality assurance. Collaborate with healthcare professionals to opti...
4 days ago
Supv, Rehabilitation Operations EX
$76K - $141K *
Champion quality improvement initiatives by developing practice changes, coordinating audits, and educating clinical teams. Engage with stakeholders and oversee clinical operations to enhance patient...
Reposted 4 days ago
$80K - $95K *
Empower developers by diagnosing and resolving complex technical issues related to APIs. Collaborate across teams, advocate for improvements, and enhance developer experiences in a fast-paced, innovat...
Reposted 4 days ago
$195K - $325K *
Join a team that's shaping the future of AI in healthcare by leading multi-year strategies, resolving complex technical challenges, and influencing executive decisions across the organization to ensur...
4 days ago
$90K - $110K *
Join a dynamic team to develop and enhance SaaS applications, utilizing Agile methodologies. Collaborate with peers, support customers, and drive innovative solutions while staying updated on technica...
4 days ago
$65K - $96K *
Advance leadership development by designing impactful programs and coaching talent. Collaborate with teams to enhance learning experiences and drive measurable success in succession planning and organ...
4 days ago
Director, Experience / Creator Events
$115K - $135K *
Join a team that's shaping innovative experiential solutions while leading client services. Oversee project delivery from concept to execution, nurture client relationships, and scale talent in a dyna...
Reposted 4 days ago
$110K - $196K *
Shape the future of K-12 education by leading product marketing strategies that drive growth and adoption. Collaborate cross-functionally to deliver compelling messaging and go-to-market initiatives t...
4 days ago
Environmental Scientist Consultant I
$75K - $86K *
Champion environmental initiatives by leading certification programs and technical reviews. Collaborate with stakeholders to enhance public health and environmental standards through education and com...
4 days ago
Human Resources Director - Onsite
$90K - $110K *
Lead the charge in shaping a dynamic HR environment, fostering collaboration, and enhancing employee engagement while driving performance management and compliance across the organization...
4 days ago
Advanced Practice Registered Nurse (DEA)
$95K - $115K *
Transform patient care delivery in radiation oncology by performing advanced assessments, managing comprehensive treatment plans, and collaborating with interdisciplinary teams to enhance patient outc...
Reposted 4 days ago
Mechanical OFCI Design Manager - Data Center Construction
$170K - $210K *
Elevate project management excellence by leading design coordination for OFCI mechanical systems in a dynamic data center environment, ensuring seamless integration and adherence to technical standard...
4 days ago
$116K - $165K *
Lead the design and integration of marine electrical systems for commercial and governmental vessels. Ensure compliance with regulatory standards while managing technical responsibilities for shipboar...
4 days ago
Accounting Team Manager (Not For Profit) - Multi-Client Exp. Required
$80K - $95K *
Advance your career by leading multi-team oversight and management in accounting operations across diverse industries. Utilize your expertise in compliance, software integration, and project managemen...
4 days ago
$88K - $105K *
Transform customer interactions by leading a diverse team to achieve performance goals. Drive operational strategies, foster an inclusive environment, and support leadership in decision-making to enha...
4 days ago
Field Service Engineer - Image Guided Therapy (Field: Charlotte, NC)
$72K - $112K *
Serve as a vital link in healthcare by providing expert technical support for imaging equipment. You'll ensure optimal performance through installation, troubleshooting, and maintenance, while fosteri...
4 days ago
Developer - AI Native Engineering
$82K - $123K *
Champion AI innovation by driving tool adoption, engineering practices, and workforce enablement across the enterprise. Collaborate with cross-functional teams, influencing leaders and building future...
Reposted 4 days ago
Patent Prosecution Customer Success Manager
$71K - $119K *
Drive customer success by leveraging expertise in intellectual property solutions, enhancing product adoption, and delivering exceptional experiences through strategic engagement and training initiati...
4 days ago
Family Nurse Practitioner - Addictions Residential
$85K - $100K *
Champion comprehensive psychiatric care for children, overseeing clinical services, program development, and staff training while ensuring quality standards and collaboration with healthcare professio...
4 days ago
Senior Strategic Account Manager, GTM
$110K - $130K *
Optimize strategic DeFi accounts by fostering relationships, driving adoption of services, and influencing product development through customer insights. Collaborate cross-functionally to ensure succe...
4 days ago
Where can I find jobs paying $100,000 or more in Kentucky?
Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.
What types of high-paying professional jobs are available in Kentucky?
Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.
Which Kentucky cities have professional job opportunities?
Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.
How can I improve my chances of getting a $100K+ job in Kentucky?
Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.
Are all jobs listed in Kentucky remote or hybrid?
Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.