Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.
Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.
Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.
Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.
Average Salary: $108,152
Construction SW Cost Management Specialist
$105K - $150K *
Empower construction teams by optimizing financial workflows and technology solutions. Serve as a subject matter expert in cost management, collaborating with stakeholders to enhance project cost cont...
4 days ago
Associate Director, Omnichannel Marketing - Prostate Cancer
$170K - $213K *
Transform customer engagement by leading omnichannel marketing strategies, collaborating with cross-functional teams, and leveraging data insights to enhance HCP and patient experiences in the pharmac...
4 days ago
Biostatistical Programming Manager
$129K - $174K *
Lead a dynamic programming team to enhance data analysis strategies, ensuring high-quality biomedical data presentation while driving efficiency and innovation in a collaborative environment focused o...
4 days ago
Director of Business Development
$135K - $150K *
Champion growth by leading strategic business development initiatives, forging partnerships, and driving revenue expansion. Collaborate with executives to align goals and enhance market presence while...
4 days ago
$160K - $200K *
Drive strategic leadership in underwriting, enhancing performance and scalability across lending channels. Collaborate with cross-functional teams to ensure sound credit decisions and regulatory compl...
4 days ago
Sr IT Project Manager with Oracle EBS - Remote
$120K - $145K *
Lead and manage large-scale Oracle E-Business Suite upgrades, coordinating cross-functional teams to ensure successful project delivery within scope, schedule, and budget while overseeing governance a...
4 days ago
Associate Director - Medical Science Liaison, Oncology (GI/Thoracic Focus) - Upper Midwest
$156K - $250K *
Lead the charge in scientific dialogue with key healthcare professionals, providing critical insights and support within your therapeutic area. Utilize your expertise to enhance patient outcomes and f...
Reposted 4 days ago
$110K - $130K *
Optimize clinical trial operations by leading cross-functional teams, managing vendor relationships, and ensuring compliance with regulatory standards to drive successful study execution and patient e...
4 days ago
Associate Director, Study Operations Manager - Nonclinical Toxicology
$129K - $231K *
Elevate nonclinical toxicology operations by managing study execution, ensuring compliance, and fostering collaboration across teams to advance innovative therapies for sleep-wake disorders. Drive acc...
4 days ago
Account Manager, Wound Reconstruction Solutions -- Los Angeles, CA
$95K - $115K *
Build strong relationships and drive sales for advanced wound care products in a defined territory. Achieve revenue targets through strategic planning, customer engagement, and exceptional service in...
Reposted 4 days ago
$120K - $145K *
Partner with us to drive customer success by implementing and expanding Teleport solutions. Leverage your expertise to enhance adoption, troubleshoot issues, and deliver tailored training, ensuring cl...
4 days ago
$100K - $120K *
Elevate revenue growth by driving sales of innovative traffic management solutions to government agencies. Collaborate with partners, identify opportunities, and build strong relationships to achieve...
4 days ago
$84K - $131K *
Engineer innovative web applications by leveraging Java and Spring Boot. Collaborate across teams to implement DevSecOps practices, ensuring secure, efficient delivery while integrating AI capabilitie...
4 days ago
Director, Rack Scale Software Architecture
$320K - $488K *
Join a team that's pushing the boundaries of innovation in rack-scale system software. Lead technical design efforts, collaborate with top industry players, and drive quality across a rapidly evolving...
Reposted 4 days ago
Enterprise Software Account Manager
$100K - $110K *
Empower corporate veterinary groups by driving software adoption and growth. Collaborate with cross-functional teams to develop strategic partnerships, influence decisions, and enhance customer satisf...
4 days ago
Senior Guidewire PolicyCenter Developer
$110K - $130K *
Collaborate with us to develop and configure Guidewire PolicyCenter solutions, enhancing the policy lifecycle for Personal and Commercial Lines of Business while integrating advanced technologies and...
4 days ago
Technical Relationship Manager (Hybrid - JP Morgan Chase, New Jersey)
$110K - $130K *
Join a team that's dedicated to fostering strategic relationships with enterprise customers, ensuring successful adoption and optimization of technology solutions in the financial services sector whil...
4 days ago
Construction SW Technical Specialist
$105K - $150K *
Join a team that's transforming construction project management through technology. Leverage your industry expertise to guide customers in adopting Autodesk solutions, enhancing workflows, and driving...
4 days ago
Architect - Platform Engineering - USA
$150K - $180K *
Join a dynamic team to architect and implement cutting-edge MLOps strategies, leveraging Google Cloud's AI/ML stack. Drive innovation in model lifecycle management and collaborate with cross-functiona...
4 days ago
$90K - $115K *
Lead the charge in enhancing customer support by guiding a skilled team of Support Engineers. Balance hands-on technical assistance with operational oversight to ensure a world-class experience for cl...
4 days ago
Cyber Security Exposure Response Lead
$100K - $170K *
Lead the charge in modernizing enterprise security by investigating and mitigating critical vulnerabilities. Collaborate across teams to drive risk reduction and enhance operational effectiveness in a...
4 days ago
Associate Clinical Research Manager
$105K - $140K *
Champion clinical trial excellence by leading a high-performing CRA team, ensuring compliance with ICH-GCP and local regulations while fostering a positive team culture and optimizing site relationshi...
4 days ago
$120K *
Join a team that's driving impactful cross-functional initiatives by leading strategic delivery efforts. Leverage your project management expertise to align complex projects with enterprise priorities...
4 days ago
$125K - $150K *
Drive regional sales growth by developing strategies, managing key accounts, and expanding market presence. Engage with K-12 leaders to enhance customer relationships and achieve sales targets while m...
4 days ago
eCommerce Experience Manager, Mobile App and Loyalty
$83K - $138K *
Lead the strategy and performance management for our mobile app and loyalty experience, driving athlete engagement and revenue growth through cross-functional collaboration and data-driven insights. O...
Reposted 4 days ago
Where can I find jobs paying $100,000 or more in Kentucky?
Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.
What types of high-paying professional jobs are available in Kentucky?
Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.
Which Kentucky cities have professional job opportunities?
Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.
How can I improve my chances of getting a $100K+ job in Kentucky?
Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.
Are all jobs listed in Kentucky remote or hybrid?
Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.