Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.
Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.
Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.
Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.
Average Salary: $108,152
Managing Director, Assessment & Human Capital
$170K - $230K *
Drive strategic growth and innovation in AI-enabled assessment and workforce solutions. Lead high-impact projects, foster collaboration, and enhance AIR's national leadership in education and workforc...
3 days ago
Senior Software Engineer - Front End/Back End (Library of Congress)
$120K - $150K *
Unlock potential by leading software engineering initiatives, mentoring junior engineers, and driving improvements in development processes. Collaborate with stakeholders to deliver impactful solution...
Reposted 3 days ago
$125K - $150K *
Join a team that's redefining asset management through innovative Oracle ERP solutions. Lead enterprise-level systems engineering to enhance financial accuracy and streamline processes, ensuring compl...
3 days ago
Sr Advanced Mechanical Engineer
$149K - $166K *
Lead the charge in advancing cutting-edge mechanical engineering solutions for high-performance electronics in space systems. Collaborate with cross-functional teams to deliver innovative designs that...
3 days ago
Senior Software Engineer | C5 SW Architect
$157K - $174K *
Join a team that's shaping the future of combat vehicle software. Lead architectural design and technical direction for mission-critical systems, integrating advanced technologies in a collaborative...
3 days ago
Director / Senior Director, Business Development - Enterprise, US
$150K - $200K *
Drive strategic revenue growth by engaging C-suite stakeholders and closing multimillion-dollar partnerships within large pharmaceutical organizations. Leverage your expertise to navigate complex sale...
3 days ago
$166K - $200K *
Shape the future of healthcare technology by leading engineering for patient-centric systems. Drive innovation, ensure compliance, and mentor teams to deliver safe, efficient clinical solutions that e...
3 days ago
$90K - $110K *
Elevate your career by managing a diverse portfolio of retail and industrial properties across multiple states. This hands-on role focuses on operational excellence, financial performance, and tenant...
3 days ago
Shreveport, LA based Clinical Specialist - Remote, USA
$100K - $140K *
Grow your career with a dynamic role in clinical support, training surgical teams, and ensuring optimal patient outcomes in complex procedures. Collaborate closely with medical professionals, manage i...
Reposted 3 days ago
Senior AI Software Engineer (Healthcare)
$120K - $145K *
Engage in cutting-edge AI development by designing and scaling intelligent applications. Leverage Generative AI and modern tools to enhance productivity and integrate workflows within healthcare platf...
Reposted 3 days ago
Senior Product Manager, Clinical Development Platforms
$155K - $200K *
Elevate product management by driving vision, strategy, and execution across digital solutions in clinical development. Collaborate with cross-functional teams to enhance user experience and operation...
3 days ago
$80K - $95K *
Shape the future of client relationships in the metals industry by driving sales, managing key accounts, and ensuring customer satisfaction. Leverage market expertise to identify opportunities and fos...
Reposted 3 days ago
Sr. Manager, IT SOX Compliance
$103K - $184K *
Transform compliance processes by leading IT SOX initiatives, ensuring robust internal controls and regulatory adherence across the organization while collaborating with cross-functional teams to miti...
3 days ago
Account Executive/Senior Account Executive
$90K - $150K *
Lead your career with a pivotal role in strategic sales, driving revenue through exceptional account management and cultivating strong relationships with agencies and clients to expand our innovative...
Reposted 3 days ago
$80K - $95K *
Drive client success by managing accounts, optimizing Meta campaigns, and fostering strong relationships. You'll lead strategy discussions, analyze performance, and ensure client satisfaction while ac...
3 days ago
$120K - $145K *
Innovate order management solutions by implementing and integrating OMS capabilities, enhancing eCommerce and fulfillment systems through complex integrations and driving continuous improvement in a f...
Reposted 3 days ago
Senior Manager, Data Engineering
$120K - $145K *
Unlock potential by managing and optimizing data and BI platforms. Collaborate with stakeholders to define architecture, drive project plans, and ensure data quality while leading a team to deliver im...
3 days ago
$170K - $180K *
Unlock potential by leading a diverse team of technical professionals to ensure timely project delivery and operational excellence. Drive collaboration, manage risks, and enhance project management pr...
3 days ago
Production Training Support Specialist
$83K - $87K *
Deliver exceptional training support by communicating complex concepts clearly, analyzing system issues, and enhancing customer experience for the VA's Vocational Readiness and Employment system. Coll...
3 days ago
Senior IT Project Manager (NSGS)
$140K - $180K *
Lead the execution of complex IT infrastructure projects, ensuring mission success for critical U.S. Coast Guard programs. Collaborate with stakeholders and manage resources to deliver seamless techno...
3 days ago
$100K - $105K *
Deliver robust testing solutions by collaborating with developers and users. Drive quality assurance in health IT systems, creating effective test plans and monitoring performance for continual improv...
Reposted 3 days ago
$75K - $96K *
Optimize AI triage and automation processes while engineering secure data pipelines. Collaborate with teams to enhance security alert resolution and streamline workflows, ensuring effective integratio...
3 days ago
$110K - $130K *
Join a team that's shaping innovative products by translating customer needs into actionable solutions. Collaborate with cross-functional teams to prioritize and deliver high-quality outcomes in a dyn...
3 days ago
Hematology/Oncology Specialist - Houston TX
$170K - $210K *
Unlock potential by driving strategic initiatives in oncology sales, fostering relationships with key stakeholders, and ensuring patient access to innovative therapies while achieving business goals t...
3 days ago
$200K - $250K *
Lead the charge in managing complex financial services litigation, providing strategic guidance to clients while collaborating with a dynamic team. Drive case resolution and compliance efforts in a fa...
3 days ago
Where can I find jobs paying $100,000 or more in Kentucky?
Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.
What types of high-paying professional jobs are available in Kentucky?
Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.
Which Kentucky cities have professional job opportunities?
Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.
How can I improve my chances of getting a $100K+ job in Kentucky?
Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.
Are all jobs listed in Kentucky remote or hybrid?
Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.