Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,150

Sort By: Relevance

$75K - $96K *

Optimize AI triage and automation processes while engineering secure data pipelines. Collaborate with teams to enhance security alert resolution and streamline workflows, ensuring effective integratio...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's shaping innovative products by translating customer needs into actionable solutions. Collaborate with cross-functional teams to prioritize and deliver high-quality outcomes in a dyn...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$170K - $210K *

Unlock potential by driving strategic initiatives in oncology sales, fostering relationships with key stakeholders, and ensuring patient access to innovative therapies while achieving business goals t...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Lead the charge in managing complex financial services litigation, providing strategic guidance to clients while collaborating with a dynamic team. Drive case resolution and compliance efforts in a fa...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$120K - $145K *

Transform your career by driving VAR growth across North America. Lead partner recruitment, develop strategic plans, and enhance sales execution to achieve sustainable revenue growth in the mid-market...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$95K - $115K *

Join a team that's committed to enhancing systems infrastructure and performance. Lead complex technical projects, mentor staff, and drive innovations in technology solutions to meet business needs an...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $118K *

Transform the lives of senior patients as a Speech Language Pathologist, evaluating and treating communication and swallowing disorders. Collaborate with a dedicated team to deliver personalized care...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $145K *

Join a team that's advancing data analytics for VA modernization initiatives. Utilize SQL and Python to drive AI-enabled insights, enhance operational workflows, and support decision-making through ri...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$145K - $220K *

Drive the development and commercialization of innovative digital solutions for federal clients. Lead cross-functional teams, engage with customers, and manage the full product lifecycle from concept...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$130K - $150K *

Engage as a cybersecurity advisor, ensuring secure, scalable cloud systems for an Army program. Collaborate with technical teams to maintain security artifacts, assess risks, and integrate security in...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$94K - $114K *

Support project risk management initiatives across various sectors, collaborating with stakeholders to identify, analyze, and mitigate risks. Lead qualitative and quantitative assessments to enhance p...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$90K - $110K *

Engage with us to lead the proposal development lifecycle, ensuring compliance and quality in federal government submissions. Collaborate with diverse teams to drive success in a dynamic small busines...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$144K - $165K *

Unlock potential by owning data architecture and reliability across domains. Collaborate with an AI-first team to design robust data pipelines, enhance analytics, and drive impactful solutions in a dy...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $144K *

Optimize our data platform by owning end-to-end data engineering projects, leveraging AI coding agents, and ensuring data quality. Collaborate with cross-functional teams to deliver reliable, maintain...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$124K - $143K *

Unlock insights as a Marketing Analytics Manager, driving data analysis across channels. Collaborate with teams to enhance reporting, measurement, and performance evaluation, while mentoring analysts...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Drive growth initiatives by identifying and nurturing new business opportunities within the Dept of Army market. Collaborate with cross-functional teams to build relationships and ensure alignment wit...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$66K - $106K *

Lead a dynamic investigative team to ensure timely case resolution, mentor staff, and uphold quality standards in fraud detection and prevention efforts. Collaborate with management to enhance workflo...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$80K - $128K *

Engage in the modernization of the National Airspace System by providing expert analysis and support for radar systems. Collaborate with FAA stakeholders to enhance air traffic management and ensure t...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$104K - $166K *

Shape the future of data integration by leading the development of robust data pipelines and enhancing fraud detection systems. Collaborate with cross-functional teams to ensure seamless data flow and...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$146K - $234K *

Innovate comprehensive security strategies for a large-scale cloud ecosystem, ensuring compliance and risk mitigation while leading cross-functional teams to protect organizational assets and enhance...

United StatesRemote

2 days ago

  •   15+ years exp.  •   Aerospace & Defense

$80K - $128K *

Develop engaging web-based training content and tools, ensuring accessibility and compliance. Collaborate on UI enhancements and create metrics dashboards to track user adoption for a federal data int...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$104K - $166K *

Elevate the performance and reliability of critical AWS cloud platforms. Collaborate with cross-functional teams to optimize infrastructure, automate processes, and ensure secure, scalable solutions t...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $128K *

Champion user interface development and API integration for a federal environmental platform, ensuring accessibility compliance and enhancing data access for regulatory consultations. Collaborate with...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$74K - $92K *

Empower our channel partner division by managing operational activities, coordinating RFPs, and driving cross-functional collaboration to enhance sales and partner engagement. Your insights will shape...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $104K *

Champion financial performance analysis for specialty pharmacy, collaborating with cross-functional teams to enhance revenue integrity and profitability through actionable insights and strategic recom...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.